Resistance of dynamin-related protein 1 oligomers to disassembly impairs mitophagy, resulting in myocardial inflammation and heart failure
动力蛋白相关蛋白1寡聚体对解离的抵抗会损害线粒体自噬,从而导致心肌炎症和心力衰竭。
期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.A115.665695
Cahill, Thomas J; Leo, Vincenzo; Kelly, Matthew; Stockenhuber, Alexander; Kennedy, Nolan W; Bao, Leyuan; Cereghetti, Grazia M; Harper, Andrew R; Czibik, Gabor; Liao, Chunyan; Bellahcene, Mohammed; Steeples, Violetta; Ghaffari, Sahar; Yavari, Arash; Mayer, Alice; Poulton, Joanna; Ferguson, David J P; Scorrano, Luca; Hettiarachchi, Nishani T; Peers, Chris; Boyle, John; Hill, R Blake; Simmons, Alison; Watkins, Hugh; Dear, T Neil; Ashrafian, Houman