日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Design, synthesis, anticancer evaluation, and in silico ADMET analysis of novel thalidomide analogs as promising immunomodulatory agents.

设计、合成、抗癌评价和计算机模拟 ADMET 分析新型沙利度胺类似物作为有前景的免疫调节剂

期刊:RSC Advances
影响因子:4.6
doi:10.1039/d3ra00066d
Kotb Anas Ramadan, Abdallah Abdallah E, Elkady Hazem, Eissa Ibrahim H, Taghour Mohammed S, Bakhotmah Dina Abed, Abdelghany Tamer M, El-Zahabi Mohamed Ayman
肿瘤
肿瘤免疫
发表日期：2023
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New benzoxazole derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, anti-proliferative evaluation, flowcytometric analysis, and in silico studies

新型苯并恶唑衍生物作为潜在的VEGFR-2抑制剂和细胞凋亡诱导剂：设计、合成、抗增殖活性评价、流式细胞术分析和计算机模拟研究

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.4
doi:10.1080/14756366.2021.2015343
Elkady, Hazem; Elwan, Alaa; El-Mahdy, Hesham A; Doghish, Ahmed S; Ismail, Ahmed; Taghour, Mohammed S; Elkaeed, Eslam B; Eissa, Ibrahim H; Dahab, Mohammed A; Mahdy, Hazem A; Khalifa, Mohamed M
EGFR
表观遗传
EGF
VEGF
凋亡
FCM
细胞生物学
发表日期：2022
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Benzoxazole derivatives as new VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, in silico studies, and antiproliferative evaluation

苯并恶唑衍生物作为新型VEGFR-2抑制剂和细胞凋亡诱导剂：设计、合成、计算机模拟研究及抗增殖活性评价

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.4
doi:10.1080/14756366.2022.2103552
Taghour, Mohammed S; Mahdy, Hazem A; Gomaa, Maher H; Aglan, Ahmed; Eldeib, Mahmoud Gomaa; Elwan, Alaa; Dahab, Mohammed A; Elkaeed, Eslam B; Alsfouk, Aisha A; Khalifa, Mohamed M; Eissa, Ibrahim H; Elkady, Hazem
EGFR
表观遗传
EGF
VEGF
凋亡
细胞生物学
发表日期：2022
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Design and synthesis of thiazolidine-2,4-diones hybrids with 1,2-dihydroquinolones and 2-oxindoles as potential VEGFR-2 inhibitors: in-vitro anticancer evaluation and in-silico studies

设计并合成噻唑烷-2,4-二酮与1,2-二氢喹诺酮和2-氧吲哚的杂合物作为潜在的VEGFR-2抑制剂：体外抗癌活性评价和计算机模拟研究

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.4
doi:10.1080/14756366.2022.2085693
Taghour, Mohammed S; Elkady, Hazem; Eldehna, Wagdy M; El-Deeb, Nehal M; Kenawy, Ahmed M; Elkaeed, Eslam B; Alsfouk, Aisha A; Alesawy, Mohamed S; Metwaly, Ahmed M; Eissa, Ibrahim H
EGFR
EGF
肿瘤
VEGF
肿瘤免疫
发表日期：2022
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New quinoline and isatin derivatives as apoptotic VEGFR-2 inhibitors: design, synthesis, anti-proliferative activity, docking, ADMET, toxicity, and MD simulation studies

新型喹啉和靛红衍生物作为凋亡性VEGFR-2抑制剂：设计、合成、抗增殖活性、分子对接、ADMET性质、毒性及分子动力学模拟研究

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.4
doi:10.1080/14756366.2022.2110869
Elkaeed, Eslam B; Taghour, Mohammed S; Mahdy, Hazem A; Eldehna, Wagdy M; El-Deeb, Nehal M; Kenawy, Ahmed M; A Alsfouk, Bshra; Dahab, Mohammed A; Metwaly, Ahmed M; Eissa, Ibrahim H; El-Zahabi, Mohamed A
EGFR
毒理研究
表观遗传
MET
EGF
VEGF
凋亡
发表日期：2022
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Design, synthesis, and biological evaluation of novel bioactive thalidomide analogs as anticancer immunomodulatory agents.

设计、合成和生物学评价新型生物活性沙利度胺类似物作为抗癌免疫调节剂

期刊:RSC Advances
影响因子:4.6
doi:10.1039/d2ra06188k
Kotb Anas Ramadan, Bakhotmah Dina A, Abdallah Abdallah E, Elkady Hazem, Taghour Mohammed S, Eissa Ibrahim H, El-Zahabi Mohamed Ayman
肿瘤
肿瘤免疫
发表日期：2022
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Design, synthesis, anti-proliferative evaluation, docking, and MD simulations studies of new thiazolidine-2,4-diones targeting VEGFR-2 and apoptosis pathway

针对VEGFR-2和细胞凋亡通路的新型噻唑烷-2,4-二酮类化合物的设计、合成、抗增殖活性评价、分子对接和分子动力学模拟研究

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0272362
Taghour, Mohammed S; Elkady, Hazem; Eldehna, Wagdy M; El-Deeb, Nehal; Kenawy, Ahmed M; Elkaeed, Eslam B; Alsfouk, Bshra A; Alesawy, Mohamed S; Husein, Dalal Z; Metwaly, Ahmed M; Eissa, Ibrahim H
信号转导
EGFR
表观遗传
EGF
VEGF
凋亡
细胞生物学
发表日期：2022
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Discovery of new 3-methylquinoxalines as potential anti-cancer agents and apoptosis inducers targeting VEGFR-2: design, synthesis, and in silico studies

发现新型3-甲基喹喔啉类化合物作为潜在的抗癌药物和凋亡诱导剂，靶向VEGFR-2：设计、合成和计算机模拟研究

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.4
doi:10.1080/14756366.2021.1945591
Alanazi, Mohammed M; Alaa, Elwan; Alsaif, Nawaf A; Obaidullah, Ahmad J; Alkahtani, Hamad M; Al-Mehizia, Abdulrahman A; Alsubaie, Sultan M; Taghour, Mohammed S; Eissa, Ibrahim H
EGFR
表观遗传
EGF
肿瘤
VEGF
凋亡
肿瘤免疫
发表日期：2021
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Design and Synthesis of New Quinoxaline Derivatives as Potential Histone Deacetylase Inhibitors Targeting Hepatocellular Carcinoma: In Silico, In Vitro, and SAR Studies

设计并合成新型喹喔啉衍生物作为潜在的组蛋白去乙酰化酶抑制剂靶向肝细胞癌：计算机模拟、体外实验和构效关系研究

期刊:Frontiers in Chemistry
影响因子:4.2
doi:10.3389/fchem.2021.725135
Ma, Chao; Taghour, Mohammed S; Belal, Amany; Mehany, Ahmed B M; Mostafa, Naglaa; Nabeeh, Ahmed; Eissa, Ibrahim H; Al-Karmalawy, Ahmed A
乙酰化
表观遗传
肿瘤
细胞生物学
肿瘤免疫
发表日期：2021
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