日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Clinical significance of non-invasive in vitro drug sensitivity profiling using pancreatic cancer organoids derived from saline flushes collected during routine EUS-FNA

利用常规超声内镜引导下细针穿刺活检术（EUS-FNA）中收集的生理盐水冲洗液衍生的胰腺癌类器官进行非侵入性体外药物敏感性分析的临床意义

期刊:Clinical & Translational Oncology
影响因子:2.5
doi:10.1007/s12094-025-04111-9
Ekawa, Tomoya; Ikezawa, Kenji; Kukita, Yoji; Urabe, Makiko; Kai, Yugo; Takada, Ryoji; Akazawa, Takashi; Mizote, Yu; Tatsumi, Kumiko; Nagata, Shigenori; Ogawa, Hisataka; Hasegawa, Shinichiro; Takahashi, Hidenori; Ohkawa, Kazuyoshi; Tahara, Hideaki
3D/类器官
胰腺癌
肿瘤
肿瘤免疫
发表日期：2026
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Relaxin-2-secreting CAR-T cells exhibit enhanced efficacy in stromal-rich xenograft tumors.

分泌松弛素-2的CAR-T细胞在基质丰富的异种移植肿瘤中表现出增强的疗效

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2025.1506204
Ogawa Hisataka, Ekawa Tomoya, Mizote Yu, Akazawa Takashi, Tahara Hideaki
肿瘤
T细胞
发表日期：2025
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Roles of C-reactive protein and LOX-1 on cancer and myeloid-derived suppressor cells in the progression of uterine cervical cancer.

C反应蛋白和LOX-1在宫颈癌进展中对癌细胞和髓系来源抑制细胞的作用

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-91858-4
Maeda Michihide, Mabuchi Seiji, Akazawa Takashi, Mizote Yu, Sasano Tomoyuki, Komura Naoko, Sakata Mina, Takiuchi Tsuyoshi, Matsuzaki Shinya, Hisa Tsuyoshi, Nakamura Harumi, Ekawa Tomoya, Kamiura Shoji, Kimura Tadashi, Tahara Hideaki
细胞生物学
发表日期：2025
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Significance of mouse xenograft tumor model using patient-derived cancer organoids for clinical drug development.

利用患者来源的癌症类器官构建小鼠异种移植肿瘤模型在临床药物开发中的意义

期刊:Frontiers in Oncology
影响因子:3.3
doi:10.3389/fonc.2025.1485886
Ogawa Hisataka, Yoshida Keiichi, Hasegawa Shinichiro, Wada Hiroshi, Yasui Masayoshi, Tahara Hideaki
肿瘤
Mouse
3D/类器官
发表日期：2025
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Potent CTLs can be induced against tumor cells in an environment of lower levels of systemic MFG-E8

在系统性 MFG-E8 水平较低的环境下，可以诱导产生针对肿瘤细胞的强效 CTL。

期刊:Cancer Science
影响因子:4.3
doi:10.1111/cas.16099
Mizote, Yu; Inoue, Takako; Akazawa, Takashi; Kunimasa, Kei; Tamiya, Motohiro; Kumamoto, Yachiyo; Tsuda, Arisa; Yoshida, Satomi; Tatsumi, Kumiko; Ekawa, Tomoya; Honma, Keiichiro; Nishino, Kazumi; Tahara, Hideaki
肿瘤细胞
细胞生物学
肿瘤
肿瘤免疫
发表日期：2024
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Eribulin mesylate exerts antitumor effects via CD103

甲磺酸艾立布林通过 CD103 发挥抗肿瘤作用

期刊:Oncoimmunology
影响因子:6.3
doi:10.1080/2162402X.2023.2218782
Oya, Kazumasa; Nakamura, Yoshiyuki; Watanabe, Rei; Tanaka, Ryota; Ichimura, Yuki; Kubota, Noriko; Matsumura, Yutaka; Tahara, Hideaki; Okiyama, Naoko; Fujimoto, Manabu; Nomura, Toshifumi; Fujisawa, Yasuhiro
肿瘤
CD103
肿瘤免疫
CD10
发表日期：2023
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The liposome of trehalose dimycolate extracted from M. bovis BCG induces antitumor immunity via the activation of dendritic cells and CD8(+) T cells

从牛分枝杆菌卡介苗中提取的海藻糖二霉菌酸酯脂质体通过激活树突状细胞和CD8(+) T细胞诱导抗肿瘤免疫。

期刊:Cancer Immunology Immunotherapy
影响因子:5.1
doi:10.1007/s00262-021-02870-2
Shiga, Masanobu; Miyazaki, Jun; Tanuma, Kozaburo; Nagumo, Yoshiyuki; Yoshino, Takayuki; Kandori, Shuya; Negoro, Hiromitsu; Kojima, Takahiro; Tanaka, Ryota; Okiyama, Naoko; Fujisawa, Yasuhiro; Watanabe, Miyuki; Yamasaki, Sho; Kiyohara, Hideyasu; Watanabe, Makoto; Sato, Taka-Aki; Tahara, Hideaki; Nishiyama, Hiroyuki; Yano, Ikuya
肿瘤
T细胞
肿瘤免疫
树突状细胞
CD8
T细胞
细胞生物学
树突状细胞
免疫/内分泌
发表日期：2021
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ASK1 suppresses NK cell-mediated intravascular tumor cell clearance in lung metastasis

ASK1抑制NK细胞介导的肺转移瘤内血管内肿瘤细胞清除

期刊:Cancer Science
影响因子:4.3
doi:10.1111/cas.14842
Fujimoto, Makoto; Kamiyama, Miki; Fuse, Kosuke; Ryuno, Hiroki; Odawara, Takeru; Furukawa, Natsuki; Yoshimatsu, Yasuhiro; Watabe, Tetsuro; Prchal-Murphy, Michaela; Sexl, Veronika; Tahara, Hideaki; Hayakawa, Yoshihiro; Sato, Takehiro; Takeda, Kohsuke; Naguro, Isao; Ichijo, Hidenori
肿瘤细胞
细胞生物学
肿瘤
肿瘤免疫
发表日期：2021
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NKG2D defines tumor-reacting effector CD8(+) T cells within tumor microenvironment

NKG2D 定义了肿瘤微环境中的肿瘤反应效应 CD8(+) T 细胞。

期刊:Cancer Science
影响因子:4.3
doi:10.1111/cas.15050
Mojic, Marija; Shitaoka, Kiyomi; Ohshima, Chikako; Ucche, Sisca; Lyu, Fulian; Hamana, Hiroshi; Tahara, Hideaki; Kishi, Hiroyuki; Hayakawa, Yoshihiro
肿瘤
T细胞
肿瘤免疫
CD8
细胞生物学
肿瘤微环境
发表日期：2021
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Conversion Surgery for Advanced Thoracic SMARCA4-Deficient Undifferentiated Tumor With Atezolizumab in Combination With Bevacizumab, Paclitaxel, and Carboplatin Treatment: A Case Report

阿特珠单抗联合贝伐珠单抗、紫杉醇和卡铂治疗晚期胸腔SMARCA4缺陷型未分化肿瘤的转化手术：病例报告

期刊:JTO Clinical and Research Reports
影响因子:3.5
doi:10.1016/j.jtocrr.2021.100235
Kunimasa, Kei; Okami, Jiro; Takenaka, Satoshi; Honma, Keiichiro; Kukita, Yoji; Nagata, Shigenori; Kawamura, Takahisa; Inoue, Takako; Tamiya, Motohiro; Kuhara, Hanako; Nishino, Kazumi; Tahara, Hideaki; Kumagai, Toru
ARC
肿瘤
肿瘤免疫
发表日期：2021
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