Takata Akemi相关文献与解析，生知库 | 链接生命科学的每一步

Takata, Akemi; Otsuka, Motoyuki; Kishikawa, Takahiro; Yamagami, Mari; Ishibashi, Rei; Sekiba, Kazuma; Suzuki, Tatsunori; Ohno, Motoko; Yamashita, Yui; Abe, Takaya; Masuzaki, Ryota; Ikenoue, Tsuneo; Koike, Kazuhiko

细胞生物学

RAS

发表日期：2017

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Mutual antagonism between hepatitis B viral mRNA and host microRNA let-7

乙型肝炎病毒mRNA与宿主microRNA let-7之间的相互拮抗作用

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/srep23237

Takata, Akemi; Otsuka, Motoyuki; Ohno, Motoko; Kishikawa, Takahiro; Yoshikawa, Takeshi; Koike, Kazuhiko

ROCK inhibition enhances microRNA function by promoting deadenylation of targeted mRNAs via increasing PAIP2 expression

ROCK抑制剂通过增加PAIP2表达促进靶mRNA的去腺苷酸化，从而增强microRNA的功能。

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gkv728

Yoshikawa, Takeshi; Wu, Jianfeng; Otsuka, Motoyuki; Kishikawa, Takahiro; Ohno, Motoko; Shibata, Chikako; Takata, Akemi; Han, Felicia; Kang, Young Jun; Chen, Chyi-Ying A; Shyu, Ann-Bin; Han, Jiahuai; Koike, Kazuhiko

Circulating RNAs as new biomarkers for detecting pancreatic cancer

循环RNA作为检测胰腺癌的新型生物标志物

期刊:World Journal of Gastroenterology

影响因子:5.4

doi:10.3748/wjg.v21.i28.8527

Kishikawa, Takahiro; Otsuka, Motoyuki; Ohno, Motoko; Yoshikawa, Takeshi; Takata, Akemi; Koike, Kazuhiko

Diagnostic and therapeutic application of noncoding RNAs for hepatocellular carcinoma

非编码RNA在肝细胞癌诊断和治疗中的应用

期刊:World Journal of Hepatology

影响因子:2.5

doi:10.4254/wjh.v7.i1.1

Shibata, Chikako; Otsuka, Motoyuki; Kishikawa, Takahiro; Ohno, Motoko; Yoshikawa, Takeshi; Takata, Akemi; Koike, Kazuhiko

Specific delivery of microRNA93 into HBV-replicating hepatocytes downregulates protein expression of liver cancer susceptible gene MICA

将microRNA93特异性递送至HBV复制的肝细胞中可下调肝癌易感基因MICA的蛋白表达。

期刊:Oncotarget

影响因子:

doi:10.18632/oncotarget.2143

Ohno, Motoko; Otsuka, Motoyuki; Kishikawa, Takahiro; Shibata, Chikako; Yoshikawa, Takeshi; Takata, Akemi; Muroyama, Ryosuke; Kowatari, Norie; Sato, Masaya; Kato, Naoya; Kuroda, Shun'ichi; Koike, Kazuhiko

MicroRNA-140 acts as a liver tumor suppressor by controlling NF-κB activity by directly targeting DNA methyltransferase 1 (Dnmt1) expression

MicroRNA-140 通过直接靶向 DNA 甲基转移酶 1 (Dnmt1) 的表达来控制 NF-κB 活性，从而发挥肝脏肿瘤抑制作用。

期刊:Hepatology

影响因子:15.8

doi:10.1002/hep.26011

Takata, Akemi; Otsuka, Motoyuki; Yoshikawa, Takeshi; Kishikawa, Takahiro; Hikiba, Yohko; Obi, Shuntaro; Goto, Tadashi; Kang, Young Jun; Maeda, Shin; Yoshida, Haruhiko; Omata, Masao; Asahara, Hiroshi; Koike, Kazuhiko

Regulation of the expression of the liver cancer susceptibility gene MICA by microRNAs.

microRNA对肝癌易感基因MICA表达的调控

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/srep02739

Kishikawa Takahiro, Otsuka Motoyuki, Yoshikawa Takeshi, Ohno Motoko, Takata Akemi, Shibata Chikako, Kondo Yuji, Akanuma Masao, Yoshida Haruhiko, Koike Kazuhiko

Current status of miRNA-targeting therapeutics and preclinical studies against gastroenterological carcinoma

目前针对胃肠道癌的miRNA靶向疗法和临床前研究现状

期刊:

影响因子:

doi:10.1186/2052-8426-1-5

Shibata, Chikako; Otsuka, Motoyuki; Kishikawa, Takahiro; Yoshikawa, Takeshi; Ohno, Motoko; Takata, Akemi; Koike, Kazuhiko

Silencing of microRNA-122 enhances interferon-α signaling in the liver through regulating SOCS3 promoter methylation

沉默microRNA-122通过调节SOCS3启动子甲基化增强肝脏中的干扰素-α信号传导。

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/srep00637

Yoshikawa, Takeshi; Takata, Akemi; Otsuka, Motoyuki; Kishikawa, Takahiro; Kojima, Kentaro; Yoshida, Haruhiko; Koike, Kazuhiko

RASAL1 is a potent regulator of hepatic stellate cell activity and liver fibrosis

RASAL1是肝星状细胞活性和肝纤维化的强效调节因子。

Mutual antagonism between hepatitis B viral mRNA and host microRNA let-7

乙型肝炎病毒mRNA与宿主microRNA let-7之间的相互拮抗作用

ROCK inhibition enhances microRNA function by promoting deadenylation of targeted mRNAs via increasing PAIP2 expression

ROCK抑制剂通过增加PAIP2表达促进靶mRNA的去腺苷酸化，从而增强microRNA的功能。

Circulating RNAs as new biomarkers for detecting pancreatic cancer

循环RNA作为检测胰腺癌的新型生物标志物

Diagnostic and therapeutic application of noncoding RNAs for hepatocellular carcinoma

非编码RNA在肝细胞癌诊断和治疗中的应用

Specific delivery of microRNA93 into HBV-replicating hepatocytes downregulates protein expression of liver cancer susceptible gene MICA

将microRNA93特异性递送至HBV复制的肝细胞中可下调肝癌易感基因MICA的蛋白表达。

MicroRNA-140 acts as a liver tumor suppressor by controlling NF-κB activity by directly targeting DNA methyltransferase 1 (Dnmt1) expression

MicroRNA-140 通过直接靶向 DNA 甲基转移酶 1 (Dnmt1) 的表达来控制 NF-κB 活性，从而发挥肝脏肿瘤抑制作用。

Regulation of the expression of the liver cancer susceptibility gene MICA by microRNAs.

microRNA对肝癌易感基因MICA表达的调控

Current status of miRNA-targeting therapeutics and preclinical studies against gastroenterological carcinoma

目前针对胃肠道癌的miRNA靶向疗法和临床前研究现状

Silencing of microRNA-122 enhances interferon-α signaling in the liver through regulating SOCS3 promoter methylation

沉默microRNA-122通过调节SOCS3启动子甲基化增强肝脏中的干扰素-α信号传导。