CRISPR-Cas9-mediated gene knockout in intestinal tumor organoids provides functional validation for colorectal cancer driver genes
利用 CRISPR-Cas9 介导的基因敲除技术在肠道肿瘤类器官中敲除结直肠癌驱动基因，为这些基因的功能验证提供了依据。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1904714116
Takeda, Haruna; Kataoka, Shiho; Nakayama, Mizuho; Ali, Mohamed A E; Oshima, Hiroko; Yamamoto, Daisuke; Park, Jun-Won; Takegami, Yujiro; An, Tadaichi; Jenkins, Nancy A; Copeland, Neal G; Oshima, Masanobu
