日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Tick saliva reprograms macrophages into immunosuppressive hubs that regulate T-cell immunity in Rhipicephalus microplus infestation

蜱虫唾液可将巨噬细胞重编程为免疫抑制中心，从而调节微小牛蜱感染中的T细胞免疫。

期刊:Communications Biology
影响因子:5.1
doi:10.1038/s42003-026-09981-5
Nakamura, Hayato; Okagawa, Tomohiro; Maekawa, Naoya; Parizi, Luís Fernando; Ikehata, Mari; Tiyamanee, Wisa; Win, Shwe Yee; Takeuchi, Hiroto; Maezono, Keisuke; Thammahakin, Passawat; Kobayashi, Shintaro; Fukuta, Mizuki; Hirano, Minato; Yoshii, Kentaro; Murata, Shiro; Ohashi, Kazuhiko; Logullo, Carlos; da Silva Vaz, Itabajara Jr; Konnai, Satoru
炎症/感染
免疫/内分泌
细胞生物学
巨噬细胞
T细胞
发育与干细胞
巨噬细胞
T细胞
发表日期：2026
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Retinoic acid receptor-related orphan receptor α regulates bystander activation of memory CD8(+) T cells

视黄酸受体相关孤儿受体α调节记忆性CD8(+) T细胞的旁观者激活

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2025.1647746
Cai, Zimeng; Kozai, Mina; Mita, Hironobu; Takeuchi, Hiroto; Mizuno, Satoru; Matsuo, Kazuhiro; Takada, Kensuke
T细胞
信号转导
CD8
T细胞
细胞生物学
免疫/内分泌
发表日期：2025
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Anti-inflammatory and renoprotective effects of difelikefalin, a kappa opioid receptor agonist, in a rat model of renal ischemia-reperfusion-induced acute kidney injury.

卡帕阿片受体激动剂二非利法林在肾脏缺血再灌注诱导的急性肾损伤大鼠模型中具有抗炎和肾脏保护作用

期刊:BMC Nephrology
影响因子:2.4
doi:10.1186/s12882-025-04199-9
Takeuchi Hiroto, Tatemichi Satoshi, Okuhara Yuji
免疫/内分泌
Rat
发表日期：2025
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Exploratory, Randomized, Dose-Response Study of the Anti-PD-L1 Antibody HFC-L1/c4G12 in Dogs with Pulmonary Metastatic Oral Malignant Melanoma

一项探索性、随机、剂量反应研究，旨在评估抗PD-L1抗体HFC-L1/c4G12在患有肺转移性口腔恶性黑色素瘤的犬中的疗效

期刊:Veterinary Sciences
影响因子:2.3
doi:10.3390/vetsci12090850
Hosoya, Kenji; Kim, Sangho; Kinoshita, Ryohei; Maekawa, Naoya; Konnai, Satoru; Takagi, Satoshi; Tagawa, Michihito; Kagawa, Yumiko; Deguchi, Tatsuya; Owaki, Ryo; Tachibana, Yurika; Yokokawa, Madoka; Takeuchi, Hiroto; Nakamura, Hayato; Yamauchi, Akinori; Kudo, Ayano; Kamo, Shintaro; Kato, Yukinari; Kanazawa, Shigeki; Abe, Tomoyuki; Furuta, Takuya; Yamamoto, Keiichi; Suzuki, Yasuhiko; Okagawa, Tomohiro; Murata, Shiro; Ohashi, Kazuhiko
PD-L1
黑色素瘤
发表日期：2025
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Clinical efficacy of anti-programmed death ligand 1 antibody HFC-L1/c4G12 in dogs with malignant tumors: an exploratory study

抗程序性死亡配体1抗体HFC-L1/c4G12治疗犬恶性肿瘤的临床疗效：一项探索性研究

期刊:Journal of Veterinary Medical Science
影响因子:1.1
doi:10.1292/jvms.25-0303
Takagi, Satoshi; Tagawa, Michihito; Maekawa, Naoya; Konnai, Satoru; Kagawa, Yumiko; Hosoya, Kenji; Yamauchi, Akinori; Kudo, Ayano; Kamo, Shintaro; Kim, Sangho; Kinoshita, Ryohei; Deguchi, Tatsuya; Owaki, Ryo; Tachibana, Yurika; Yokokawa, Madoka; Takeuchi, Hiroto; Nakamura, Hayato; Kato, Yukinari; Kanazawa, Shigeki; Abe, Tomoyuki; Furuta, Takuya; Yamamoto, Keiichi; Suzuki, Yasuhiko; Okagawa, Tomohiro; Murata, Shiro; Ohashi, Kazuhiko
肿瘤
肿瘤免疫
发表日期：2025
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Enhanced Systemic Antitumour Immunity by Hypofractionated Radiotherapy and Anti-PD-L1 Therapy in Dogs with Pulmonary Metastatic Oral Malignant Melanoma

低分割放射疗法和抗PD-L1疗法增强犬肺转移性口腔恶性黑色素瘤的全身抗肿瘤免疫力

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers15113013
Deguchi, Tatsuya; Maekawa, Naoya; Konnai, Satoru; Owaki, Ryo; Hosoya, Kenji; Morishita, Keitaro; Nakamura, Motoji; Okagawa, Tomohiro; Takeuchi, Hiroto; Kim, Sangho; Kinoshita, Ryohei; Tachibana, Yurika; Yokokawa, Madoka; Takagi, Satoshi; Kato, Yukinari; Suzuki, Yasuhiko; Murata, Shiro; Ohashi, Kazuhiko
免疫/内分泌
PD-L1
黑色素瘤
肿瘤
肿瘤免疫
发表日期：2023
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Molecular characterization of feline immune checkpoint molecules and establishment of PD-L1 immunohistochemistry for feline tumors

猫免疫检查点分子的分子特征分析及猫肿瘤PD-L1免疫组织化学检测方法的建立

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0281143
Maekawa, Naoya; Konnai, Satoru; Asano, Yumie; Otsuka, Takumi; Aoki, Eri; Takeuchi, Hiroto; Kato, Yukinari; Kaneko, Mika K; Yamada, Shinji; Kagawa, Yumiko; Nishimura, Maki; Takagi, Satoshi; Deguchi, Tatsuya; Ohta, Hiroshi; Nakagawa, Takayuki; Suzuki, Yasuhiko; Okagawa, Tomohiro; Murata, Shiro; Ohashi, Kazuhiko
肿瘤
IHC
肿瘤免疫
PD-L1
免疫/内分泌
发表日期：2023
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Safety and clinical efficacy of an anti-PD-L1 antibody (c4G12) in dogs with advanced malignant tumours

抗PD-L1抗体（c4G12）在患有晚期恶性肿瘤的犬中的安全性和临床疗效

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0291727
Maekawa, Naoya; Konnai, Satoru; Hosoya, Kenji; Kim, Sangho; Kinoshita, Ryohei; Deguchi, Tatsuya; Owaki, Ryo; Tachibana, Yurika; Yokokawa, Madoka; Takeuchi, Hiroto; Kagawa, Yumiko; Takagi, Satoshi; Ohta, Hiroshi; Kato, Yukinari; Yamamoto, Satoshi; Yamamoto, Keiichi; Suzuki, Yasuhiko; Okagawa, Tomohiro; Murata, Shiro; Ohashi, Kazuhiko
PD-L1
肿瘤
肿瘤免疫
发表日期：2023
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