日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Glucosylceramide synthase inhibition reduces ganglioside GM3 accumulation, alleviates amyloid neuropathology, and stabilizes remote contextual memory in a mouse model of Alzheimer's disease

葡萄糖神经酰胺合酶抑制可减少神经节苷脂 GM3 的积累，减轻淀粉样神经病理学，并稳定阿尔茨海默病小鼠模型中的远程情境记忆

期刊:Alzheimers Research & Therapy
影响因子:7.9
doi:10.1186/s13195-022-00966-0
James C Dodge, Thomas J Tamsett, Christopher M Treleaven, Tatyana V Taksir, Peter Piepenhagen, S Pablo Sardi, Seng H Cheng, Lamya S Shihabuddin
神经
发表日期：2022
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Neutral Lipid Cacostasis Contributes to Disease Pathogenesis in Amyotrophic Lateral Sclerosis

中性脂质沉积导致肌萎缩侧索硬化症的发病机制

期刊:Journal of Neuroscience
影响因子:4.4
doi:10.1523/JNEUROSCI.1388-20.2020
James C Dodge, Elizabeth H Jensen, Jinlong Yu, S Pablo Sardi, Allison R Bialas, Tatyana V Taksir, Dinesh S Bangari, Lamya S Shihabuddin
免疫
神经
多发性硬化症
Donkey
发表日期：2020
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Gene delivery of a modified antibody to Aβ reduces progression of murine Alzheimer's disease

将修饰抗体基因导入小鼠体内可减缓小鼠阿尔茨海默病的发展进程。

期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0226245
Bradford M Elmer ，Kurt A Swanson ，Dinesh S Bangari ，Peter A Piepenhagen ，Errin Roberts ，Tatyana Taksir ，Lei Guo ，Maria-Carmen Obinu ，Pascal Barneoud ，Susan Ryan ，Bailin Zhang ，Laurent Pradier ，Zhi-Yong Yang ，Gary J Nabel
阿尔茨海默症
发表日期：2019
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Silencing mutant huntingtin by adeno-associated virus-mediated RNA interference ameliorates disease manifestations in the YAC128 mouse model of Huntington's disease

利用腺相关病毒介导的RNA干扰沉默突变亨廷顿蛋白可改善亨廷顿病YAC128小鼠模型的疾病症状。

期刊:Human Gene Therapy
影响因子:4
doi:10.1089/hum.2013.200
Stanek, Lisa M; Sardi, Sergio P; Mastis, Bryan; Richards, Amy R; Treleaven, Christopher M; Taksir, Tatyana; Misra, Kuma; Cheng, Seng H; Shihabuddin, Lamya S
微生物学
发表日期：2014
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Optimization of a histopathological biomarker for sphingomyelin accumulation in acid sphingomyelinase deficiency

优化酸性鞘磷脂酶缺乏症中鞘磷脂积累的组织病理学生物标志物

期刊:Journal of Histochemistry & Cytochemistry
影响因子:1.5
doi:10.1369/0022155412451129
Taksir, Tatyana V; Johnson, Jennifer; Maloney, Colleen L; Yandl, Emily; Griffiths, Denise; Thurberg, Beth L; Ryan, Susan
发表日期：2012
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Comparative analysis of acid sphingomyelinase distribution in the CNS of rats and mice following intracerebroventricular delivery

脑室内给药后大鼠和小鼠中枢神经系统酸性鞘磷脂酶分布的比较分析

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0016313
Treleaven, Christopher M; Tamsett, Thomas; Fidler, Jonathan A; Taksir, Tatyana V; Cheng, Seng H; Shihabuddin, Lamya S; Dodge, James C
Rat
神经科学
发表日期：2011
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Delivery of AAV-IGF-1 to the CNS extends survival in ALS mice through modification of aberrant glial cell activity

将AAV-IGF-1递送至中枢神经系统可通过调节异常的神经胶质细胞活性延长ALS小鼠的生存期。

期刊:Molecular Therapy
影响因子:12
doi:10.1038/mt.2008.60
Dodge, James C; Haidet, Amanda M; Yang, Wendy; Passini, Marco A; Hester, Mark; Clarke, Jennifer; Roskelley, Eric M; Treleaven, Christopher M; Rizo, Liza; Martin, Heather; Kim, Soo H; Kaspar, Rita; Taksir, Tatyana V; Griffiths, Denise A; Cheng, Seng H; Shihabuddin, Lamya S; Kaspar, Brian K
胶质细胞
ALS
细胞生物学
神经科学
IGF-1
发表日期：2008
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Temporal neuropathologic and behavioral phenotype of 6neo/6neo Pompe disease mice

6neo/6neo庞贝病小鼠的时间神经病理学和行为表型

期刊:Journal of Neuropathology and Experimental Neurology
影响因子:3
doi:10.1097/NEN.0b013e3181815994
Sidman, Richard L; Taksir, Tatyana; Fidler, Jonathan; Zhao, Michael; Dodge, James C; Passini, Marco A; Raben, Nina; Thurberg, Beth L; Cheng, Seng H; Shihabuddin, Lamya S
发表日期：2008
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Gene transfer of human acid sphingomyelinase corrects neuropathology and motor deficits in a mouse model of Niemann-Pick type A disease

人类酸性鞘磷脂酶基因转移可纠正尼曼-匹克A型疾病小鼠模型中的神经病理学和运动障碍。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.0509062102
Dodge, James C; Clarke, Jennifer; Song, Antonius; Bu, Jie; Yang, Wendy; Taksir, Tatyana V; Griffiths, Denise; Zhao, Michael A; Schuchman, Edward H; Cheng, Seng H; O'Riordan, Catherine R; Shihabuddin, Lamya S; Passini, Marco A; Stewart, Gregory R
发表日期：2005
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Intracerebral transplantation of adult mouse neural progenitor cells into the Niemann-Pick-A mouse leads to a marked decrease in lysosomal storage pathology

将成年小鼠神经祖细胞脑内移植到尼曼-匹克A型小鼠体内，可显著降低溶酶体贮积症的病理特征。

期刊:Journal of Neuroscience
影响因子:
doi:10.1523/JNEUROSCI.3584-04.2004
Shihabuddin, L S; Numan, S; Huff, M R; Dodge, J C; Clarke, J; Macauley, S L; Yang, W; Taksir, T V; Parsons, G; Passini, M A; Gage, F H; Stewart, G R
细胞生物学
神经科学
发表日期：2004
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