日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

AL101, a gamma-secretase inhibitor, has potent antitumor activity against adenoid cystic carcinoma with activated NOTCH signaling

AL101 是一种 γ-分泌酶抑制剂,对激活 NOTCH 信号的腺样囊性癌具有强效抗肿瘤活性

Renata Ferrarotto #, Vasudha Mishra #, Elad Herz, Adar Yaacov, Oz Solomon, Rami Rauch, Adi Mondshine, Maria Motin, Tal Leibovich-Rivkin, Matti Davis, Joel Kaye, Christopher R Weber, Le Shen, Alexander T Pearson, Ari J Rosenberg, Xiangying Chen, Alka Singh, Jon C Aster, Nishant Agrawal, Evgeny Izumch

The inflammatory cytokine TNFα cooperates with Ras in elevating metastasis and turns WT-Ras to a tumor-promoting entity in MCF-7 cells

炎症细胞因子 TNFα 与 Ras 协同作用,促进转移,并将 WT-Ras 转变为 MCF-7 细胞中的促肿瘤实体

Tal Leibovich-Rivkin, Yulia Liubomirski, Tsipi Meshel, Anastasia Abashidze, Daphna Brisker, Hilla Solomon, Varda Rotter, Miguel Weil, Adit Ben-Baruch

Progression of luminal breast tumors is promoted by ménage à trois between the inflammatory cytokine TNFα and the hormonal and growth-supporting arms of the tumor microenvironment

管腔型乳腺肿瘤的进展是由炎症细胞因子TNFα与肿瘤微环境中的激素和生长支持因子之间的相互作用促进的。

Polina Weitzenfeld ,Nurit Meron ,Tal Leibovich-Rivkin ,Tsipi Meshel ,Adit Ben-Baruch

Inflammatory factors of the tumor microenvironment induce plasticity in nontransformed breast epithelial cells: EMT, invasion, and collapse of normally organized breast textures

肿瘤微环境的炎症因素诱导未转化乳腺上皮细胞的可塑性:EMT、侵袭和正常组织的乳腺纹理崩塌

Tal Leibovich-Rivkin, Yulia Liubomirski, Biana Bernstein, Tsipi Meshel, Adit Ben-Baruch

Tumor-promoting circuits that regulate a cancer-related chemokine cluster: dominance of inflammatory mediators over oncogenic alterations

调节癌症相关趋化因子簇的肿瘤促进回路:炎症介质对致癌改变的主导作用

Tal Leibovich-Rivkin, Yosef Buganim, Hilla Solomon, Tsipi Meshel, Varda Rotter, Adit Ben-Baruch

Inflammatory mediators in breast cancer: coordinated expression of TNFα & IL-1β with CCL2 & CCL5 and effects on epithelial-to-mesenchymal transition

乳腺癌中的炎症介质:TNFα 和 IL-1β 与 CCL2 和 CCL5 的协调表达及其对上皮-间质转化的影响

Gali Soria, Maya Ofri-Shahak, Ilana Haas, Neora Yaal-Hahoshen, Leonor Leider-Trejo, Tal Leibovich-Rivkin, Polina Weitzenfeld, Tsipi Meshel, Esther Shabtai, Mordechai Gutman, Adit Ben-Baruch