Taldone Tony相关文献与解析，生知库 | 链接生命科学的每一步

Dunphy, Mark P S; Pressl, Christina; Pillarsetty, Nagavarakishore; Grkovski, Milan; Modi, Shanu; Jhaveri, Komal; Norton, Larry; Beattie, Bradley J; Zanzonico, Pat B; Zatorska, Danuta; Taldone, Tony; Ochiana, Stefan O; Uddin, Mohammad M; Burnazi, Eva M; Lyashchenko, Serge K; Hudis, Clifford A; Bromberg, Jacqueline; Schöder, Heiko M; Fox, Josef J; Zhang, Hanwen; Chiosis, Gabriela; Lewis, Jason S; Larson, Steven M

Human

肿瘤

肿瘤免疫

发表日期：2020

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A Chemical Biology Approach to the Chaperome in Cancer-HSP90 and Beyond

癌症分子伴侣的化学生物学研究——HSP90及其他

期刊:Cold Spring Harbor Perspectives in Biology

影响因子:8.4

doi:10.1101/cshperspect.a034116

Taldone, Tony; Wang, Tai; Rodina, Anna; Pillarsetty, Naga Vara Kishore; Digwal, Chander S; Sharma, Sahil; Yan, Pengrong; Joshi, Suhasini; Pagare, Piyusha P; Bolaender, Alexander; Roboz, Gail J; Guzman, Monica L; Chiosis, Gabriela

Measuring Tumor Epichaperome Expression Using [(124)I] PU-H71 Positron Emission Tomography as a Biomarker of Response for PU-H71 Plus Nab-Paclitaxel in HER2-Negative Metastatic Breast Cancer

利用[(124)I]PU-H71正电子发射断层扫描测量肿瘤表观分子伴侣表达，作为PU-H71联合白蛋白紫杉醇治疗HER2阴性转移性乳腺癌疗效的生物标志物

期刊:Jco Precision Oncology

影响因子:5.6

doi:10.1200/PO.20.00273

Jhaveri, Komal L; Dos Anjos, Carlos H; Taldone, Tony; Wang, Rui; Comen, Elizabeth; Fornier, Monica; Bromberg, Jacqueline F; Ma, Weining; Patil, Sujata; Rodina, Anna; Pillarsetty, Nagavarakishore; Duggan, Susan; Khoshi, Sarhe; Kadija, Nathan; Chiosis, Gabriela; Dunphy, Mark P; Modi, Shanu

Structures of Hsp90α and Hsp90β bound to a purine-scaffold inhibitor reveal an exploitable residue for drug selectivity

Hsp90α和Hsp90β与嘌呤骨架抑制剂结合的结构揭示了一个可用于药物选择性的残基。

期刊:Proteins-Structure Function and Bioinformatics

影响因子:2.8

doi:10.1002/prot.25750

Huck, John D; Que, Nanette L S; Sharma, Sahil; Taldone, Tony; Chiosis, Gabriela; Gewirth, Daniel T

发表日期：2019

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Copper Mediated Coupling of 2-(Piperazine)-pyrimidine Iodides with Aryl Thiols using Cu(I)Thiophene-2-carboxylate

利用 Cu(I)噻吩-2-羧酸酯催化 2-(哌嗪)-嘧啶碘化物与芳基硫醇的铜介导偶联反应

期刊:Tetrahedron Letters

影响因子:1.5

doi:10.1016/j.tetlet.2017.10.041

Shrestha, Liza; Patel, Hardik J; Kang, Yanlong; Sharma, Sahil; Chiosis, Gabriela; Taldone, Tony

发表日期：2017

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Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomas

靶向核输出和RNA翻译的组合疗法可抑制侵袭性B细胞淋巴瘤

期刊:Blood

影响因子:23.1

doi:10.1182/blood-2015-05-645069

Culjkovic-Kraljacic, Biljana; Fernando, Tharu M; Marullo, Rossella; Calvo-Vidal, Nieves; Verma, Akanksha; Yang, ShaoNing; Tabbò, Fabrizio; Gaudiano, Marcello; Zahreddine, Hiba; Goldstein, Rebecca L; Patel, Jayeshkumar; Taldone, Tony; Chiosis, Gabriela; Ladetto, Marco; Ghione, Paola; Machiorlatti, Rodolfo; Elemento, Olivier; Inghirami, Giorgio; Melnick, Ari; Borden, Katherine L B; Cerchietti, Leandro

Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and Î±-Synuclein Accumulation.

Parkin 和 PINK1 患者的 iPSC 衍生的中脑多巴胺神经元表现出线粒体功能障碍和 α-突触核蛋白积累

期刊:Stem Cell Reports

影响因子:5.1

doi:10.1016/j.stemcr.2016.08.012

Chung Sun Young, Kishinevsky Sarah, Mazzulli Joseph R, Graziotto John, Mrejeru Ana, Mosharov Eugene V, Puspita Lesly, Valiulahi Parvin, Sulzer David, Milner Teresa A, Taldone Tony, Krainc Dimitri, Studer Lorenz, Shim Jae-Won

Heat Shock Protein (HSP) Drug Discovery and Development: Targeting Heat Shock Proteins in Disease

热休克蛋白（HSP）药物发现与开发：靶向疾病中的热休克蛋白

期刊:Current Topics in Medicinal Chemistry

影响因子:3.3

doi:10.2174/1568026616666160413141911

Shrestha, Liza; Bolaender, Alexander; Patel, Hardik J; Taldone, Tony

发表日期：2016

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Radiosynthesis of the iodine-124 labeled Hsp90 inhibitor PU-H71

碘-124标记的Hsp90抑制剂PU-H71的放射合成

期刊:Journal of Labelled Compounds & Radiopharmaceuticals

影响因子:0.9

doi:10.1002/jlcr.3369

Taldone, Tony; Zatorska, Danuta; Ochiana, Stefan O; Smith-Jones, Peter; Koziorowski, Jacek; Dunphy, Mark P; Zanzonico, Pat; Bolaender, Alexander; Lewis, Jason S; Larson, Steven M; Chiosis, Gabriela; Pillarsetty, Naga Vara Kishore

发表日期：2016

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Identification of an allosteric pocket on human hsp70 reveals a mode of inhibition of this therapeutically important protein

人 HSP70 蛋白上变构口袋的鉴定揭示了一种抑制这种具有重要治疗价值的蛋白质的机制。

期刊:

影响因子:

doi:10.1016/j.chembiol.2013.10.008

Rodina, Anna; Patel, Pallav D; Kang, Yanlong; Patel, Yogita; Baaklini, Imad; Wong, Michael J H; Taldone, Tony; Yan, Pengrong; Yang, Chenghua; Maharaj, Ronnie; Gozman, Alexander; Patel, Maulik R; Patel, Hardik J; Chirico, William; Erdjument-Bromage, Hediye; Talele, Tanaji T; Young, Jason C; Chiosis, Gabriela

First-in-Human Trial of Epichaperome-Targeted PET in Patients with Cancer

首次在癌症患者中开展针对表皮分子伴侣靶向PET的人体试验

A Chemical Biology Approach to the Chaperome in Cancer-HSP90 and Beyond

癌症分子伴侣的化学生物学研究——HSP90及其他

Measuring Tumor Epichaperome Expression Using [(124)I] PU-H71 Positron Emission Tomography as a Biomarker of Response for PU-H71 Plus Nab-Paclitaxel in HER2-Negative Metastatic Breast Cancer

利用[(124)I]PU-H71正电子发射断层扫描测量肿瘤表观分子伴侣表达，作为PU-H71联合白蛋白紫杉醇治疗HER2阴性转移性乳腺癌疗效的生物标志物

Structures of Hsp90α and Hsp90β bound to a purine-scaffold inhibitor reveal an exploitable residue for drug selectivity

Hsp90α和Hsp90β与嘌呤骨架抑制剂结合的结构揭示了一个可用于药物选择性的残基。

Copper Mediated Coupling of 2-(Piperazine)-pyrimidine Iodides with Aryl Thiols using Cu(I)Thiophene-2-carboxylate

利用 Cu(I)噻吩-2-羧酸酯催化 2-(哌嗪)-嘧啶碘化物与芳基硫醇的铜介导偶联反应

Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomas

靶向核输出和RNA翻译的组合疗法可抑制侵袭性B细胞淋巴瘤

Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and Î±-Synuclein Accumulation.

Parkin 和 PINK1 患者的 iPSC 衍生的中脑多巴胺神经元表现出线粒体功能障碍和 α-突触核蛋白积累

Heat Shock Protein (HSP) Drug Discovery and Development: Targeting Heat Shock Proteins in Disease

热休克蛋白（HSP）药物发现与开发：靶向疾病中的热休克蛋白

Radiosynthesis of the iodine-124 labeled Hsp90 inhibitor PU-H71

碘-124标记的Hsp90抑制剂PU-H71的放射合成

Identification of an allosteric pocket on human hsp70 reveals a mode of inhibition of this therapeutically important protein

人 HSP70 蛋白上变构口袋的鉴定揭示了一种抑制这种具有重要治疗价值的蛋白质的机制。