日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Structure-activity relationship studies on 2-thienylidene substituted 3-oxo-2,3-dihydrobenzofuran-7-carboxamides as poly (ADP-ribose) polymerase inhibitors

2-噻吩亚甲基取代的3-氧代-2,3-二氢苯并呋喃-7-甲酰胺作为聚（ADP-核糖）聚合酶抑制剂的构效关系研究

期刊:Bioorganic Chemistry
影响因子:4.7
doi:10.1016/j.bioorg.2025.108941
Salami, Abosede; Adiele, Ugochi; Coate, Griffin; Diolaiti, Morgan; Chen, Huadong; Lu, Junhao; Ashworth, Alan; Patil, Manisha; Fleishman, Joshua S; Ramaraju, Andhavaram; Patel, Akanksha; Patel, Himaxi; Patel, Ketankumar; Murakami, Megumi; Ambudkar, Suresh V; Talele, Tanaji T
发表日期：2025
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Discovery of a Novel [6-6-5-5-6] Pentacyclic Tetrahydrocyclopentaphthalazinone as a Promising PARP Inhibitor Scaffold

发现一种新型[6-6-5-5-6]五环四氢环戊酞嗪酮作为有前景的PARP抑制剂骨架

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.4c00603
Doruk, Yagmur U; Diolaiti, Morgan E; Ashworth, Alan; Talele, Tanaji T
PARP
发表日期：2025
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Highly Sensitive Multiplexed Detection of Brain‐Derived Tau and Phosphorylated Tau Proteoforms with the NULISA Technology

利用NULISA技术对脑源性tau蛋白和磷酸化tau蛋白进行高灵敏度多重检测

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-33613-3
Wang, Yi-Jun; Patel, Bhargav A; Anreddy, Nagaraju; Zhang, Yun-Kai; Zhang, Guan-Nan; Alqahtani, Saeed; Singh, Satyakam; Shukla, Suneet; Kaddoumi, Amal; Ambudkar, Suresh V; Talele, Tanaji T; Chen, Zhe-Sheng; Ma, Xiao‐Jun; Iyengar, Shweta; Deshmukh, Shalaka; Comandor, Roopa; Wang, Li; Kim, Sean; Xu, Xiaomei; Feng, Wei; Qiu, Xiaolei; Zhang, Bingqing; Luo, Yuling
信号转导
磷酸化
神经科学
发表日期：2025
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Identification of a novel spirocyclic Nek2 inhibitor using high throughput virtual screening

利用高通量虚拟筛选鉴定一种新型螺环Nek2抑制剂

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2023.129288
Bhuiyan, Ashif I; Choi, Athena H; Ghoshal, Sarbani; Adiele, Ugochi A; Dana, Dibyendu; Choi, Jun Yong; Fath, Karl R; Talele, Tanaji T; Pathak, Sanjai K
发表日期：2023
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Structural basis for allosteric PARP-1 retention on DNA breaks

DNA断裂处PARP-1变构保留的结构基础

期刊:Science
影响因子:45.8
doi:10.1126/science.aax6367
Zandarashvili, Levani; Langelier, Marie-France; Velagapudi, Uday Kiran; Hancock, Mark A; Steffen, Jamin D; Billur, Ramya; Hannan, Zain M; Wicks, Andrew J; Krastev, Dragomir B; Pettitt, Stephen J; Lord, Christopher J; Talele, Tanaji T; Pascal, John M; Black, Ben E
PARP
发表日期：2020
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Thiazole-valine peptidomimetic (TTT-28) antagonizes multidrug resistance in vitro and in vivo by selectively inhibiting the efflux activity of ABCB1

噻唑-缬氨酸肽模拟物（TTT-28）通过选择性抑制ABCB1的外排活性，在体外和体内拮抗多药耐药性。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/srep42106
Wang, Yi-Jun; Patel, Bhargav A; Anreddy, Nagaraju; Zhang, Yun-Kai; Zhang, Guan-Nan; Alqahtani, Saeed; Singh, Satyakam; Shukla, Suneet; Kaddoumi, Amal; Ambudkar, Suresh V; Talele, Tanaji T; Chen, Zhe-Sheng
ABCB1
发表日期：2017
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Motesanib (AMG706), a potent multikinase inhibitor, antagonizes multidrug resistance by inhibiting the efflux activity of the ABCB1.

Motesanib (AMG706) 是一种强效的多激酶抑制剂，它通过抑制 ABCB1 的外排活性来拮抗多药耐药性

期刊:Biochemical Pharmacology
影响因子:5.6
doi:10.1016/j.bcp.2014.06.006
Wang Yi-Jun, Kathawala Rishil J, Zhang Yun-Kai, Patel Atish, Kumar Priyank, Shukla Suneet, Fung King Leung, Ambudkar Suresh V, Talele Tanaji T, Chen Zhe-Sheng
信号转导
发表日期：2014
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Design, synthesis, and biological evaluation of (S)-valine thiazole-derived cyclic and noncyclic peptidomimetic oligomers as modulators of human P-glycoprotein (ABCB1)

设计、合成和生物学评价（S）-缬氨酸噻唑衍生的环状和非环状肽模拟寡聚体作为人类P-糖蛋白（ABCB1）调节剂

期刊:Chembiochem
影响因子:2.8
doi:10.1002/cbic.201300565
Singh, Satyakam; Prasad, Nagarajan Rajendra; Kapoor, Khyati; Chufan, Eduardo E; Patel, Bhargav A; Ambudkar, Suresh V; Talele, Tanaji T
ABCB1
发表日期：2014
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Synthesis and characterization of celecoxib derivatives as possible anti-inflammatory, analgesic, antioxidant, anticancer and anti-HCV agents

合成和表征塞来昔布衍生物作为潜在的抗炎、镇痛、抗氧化、抗癌和抗丙型肝炎病毒药物

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules18033595
Küçükgüzel, Ş Güniz; Coşkun, İnci; Aydın, Sevil; Aktay, Göknur; Gürsoy, Şule; Çevik, Özge; Özakpınar, Özlem Bingöl; Özsavcı, Derya; Şener, Azize; Kaushik-Basu, Neerja; Basu, Amartya; Talele, Tanaji T
肿瘤免疫
微生物学
肿瘤
肝炎
发表日期：2013
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Design and synthesis of L- and D-phenylalanine derived rhodanines with novel C5-arylidenes as inhibitors of HCV NS5B polymerase

设计和合成以新型C5-亚芳基取代的L-和D-苯丙氨酸衍生的罗丹宁类化合物作为HCV NS5B聚合酶抑制剂

期刊:Bioorganic & Medicinal Chemistry
影响因子:3
doi:10.1016/j.bmc.2013.03.041
Patel, Bhargav A; Krishnan, Ramalingam; Khadtare, Nikhil; Gurukumar, K R; Basu, Amartya; Arora, Payal; Bhatt, Aaditya; Patel, Maulik R; Dana, Dibyendu; Kumar, Sanjai; Kaushik-Basu, Neerja; Talele, Tanaji T
发表日期：2013
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