Tam Joseph相关文献与解析，生知库 | 链接生命科学的每一步

Endocannabinoid responses to relief of obstruction in acute injured kidney: a prospective observational study

急性肾损伤后内源性大麻素对梗阻解除的反应：一项前瞻性观察研究

Rothner, Ariel; Fishberg, Sharon E; Hinden, Liad; Atias, Eyal; Nemirovski, Alina; Gofrit, Ofer N; Tam, Joseph; Hidas, Guy

毒理研究

肾损伤

发表日期：2026

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Markedly Low Prevalence of Fatty Liver Despite Obesity in Prader-Willi Syndrome: A Search for Protective Genetic Markers

尽管普拉德-威利综合征患者肥胖，但脂肪肝患病率却显著偏低：寻找保护性遗传标记

期刊:Journal of Clinical and Experimental Hepatology

影响因子:3.2

doi:10.1016/j.jceh.2025.103155

Murik, Omer; Gross-Tsur, Varda; Mann, Tzvia; Zeevi, David A; Baraghithy, Saja; Altarescu, Gheona; Tam, Joseph; Hirsch, Harry J; Shteyer, Eyal

Blockade of Interleukin-6 Trans-signaling in the Presence of Certain Gut Microbiota Induces Mature-onset Obesity in Mice

在特定肠道菌群存在的情况下阻断白细胞介素-6反式信号传导可诱导小鼠发生成年期肥胖

期刊:Gastro Hep Advances

影响因子:

doi:10.1016/j.gastha.2025.100819

Lanton, Tali; Eidelshtein, Dana; Rachmilewitz, Jacob; Abramovitch, Rinat; Pappo, Orit; Udi, Shiran; Baraghithy, Saja; Tam, Joseph; Perles, Sharon; Williams, Evan; Elgavish, Sharona; Ruppo, Shmuel; Benyamini, Hadar; Mor, Uria; Elinav, Eran; Schmidt-Arras, Dirk; Rehman, Ateequr; Rosenstiel, Philip; Giannou, Anastasios; Huber, Samuel; Rose-John, Stefan; Galun, Eithan; Axelrod, Jonathan H

Hepatic CB1 receptor signaling triggers G(i/o)α-mediated lipolysis in lean mice but G(s)α-mediated lipogenesis in obese mice

肝脏CB1受体信号传导在瘦小鼠中触发G(i/o)α介导的脂肪分解，但在肥胖小鼠中触发G(s)α介导的脂肪生成。

期刊:Metabolism-Clinical and Experimental

影响因子:11.9

doi:10.1016/j.metabol.2025.156308

Liu, Jie; Oliverio, Anna; Godlewski, Grzegorz; Kočvarová, Radka; Arif, Muhammad; Basu, Abhishek; Guan, Yukun; Feng, Dechun; Puhl, Henry L; Iyer, Malliga R; Cinar, Resat; Gao, Bin; Tam, Joseph; Kunos, George

Correction: Pharmaceutical targeting of the cannabinoid type 1 receptor impacts the crosstalk between immune cells and islets to reduce insulitis in humans

更正：药物靶向大麻素1型受体可影响免疫细胞与胰岛之间的相互作用，从而减轻人类胰岛炎。

期刊:Diabetologia

影响因子:10.2

doi:10.1007/s00125-025-06372-z

Wreven, Elise; de Adana, María Soledad Ruiz; Hardivillé, Stéphan; Gmyr, Valery; Kerr-Conte, Julie; Chetboun, Mikael; Pasquetti, Gianni; Delalleau, Nathalie; Thévenet, Julien; Coddeville, Anaïs; Herrera, María José Vallejo; Hinden, Liad; Espínola, Inmaculada Concepción Benavides; Duro, Mireia Gómez; Salido, Lourdes Sanchez; Linares, Francisca; Bermúdez-Silva, Francisco-Javier; Tam, Joseph; Bonner, Caroline; Egan, Josephine M; Olveira, Gabriel; Colomo, Natalia; Pattou, François; González-Mariscal, Isabel

Deep brain stimulation surgical timing, outcomes, and prognostic factors in patients with Parkinson's disease: A Chinese retrospective multicenter cohort study

帕金森病患者深部脑刺激手术时机、疗效及预后因素：一项中国回顾性多中心队列研究

期刊:PLoS Medicine

影响因子:9.9

doi:10.1371/journal.pmed.1004670

Wang, Shu; Hu, Wei; Gao, Yuan; Wang, Anxin; Chen, Ling; Liang, Zhanhua; Zhang, Shizhong; Long, Hao; Li, Weiguo; Niu, Chaoshi; Liu, Weiguo; Cai, Guoen; Ji, Yuchen; Tam, Joseph; Xu, Qin; Yang, Anchao; Shi, Lin; Zhang, Hua; Han, Chunlei; Zhu, Guanyu; Bai, Yutong; Jiang, Lulu; Li, Tao; Xue, Shan; Wang, Hongxiao; Li, Yuexuan; Xiong, Chi; Lozano, Andres M; Ramirez-Zamora, Adolfo; Zhang, Wenbin; Meng, Fangang; Zhang, Jianguo

Synthesis and Pharmacological Characterization of Novel Peripheral Cannabinoid-1 Receptor Blockers Based on a Tricyclic Scaffold

基于三环骨架的新型外周大麻素-1受体阻滞剂的合成及药理学表征

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.4c03132

Gammal, Asaad; Nassar, Taher; Soae, Yael; Freeman, Noam; Badihi, Amit; Baraghithy, Saja; Nemirovski, Alina; Tam, Joseph; Benita, Simon

信号转导

发表日期：2025

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Metabolic consequences of altered kidney glucose reabsorption under normoglycemic conditions.

正常血糖条件下肾脏葡萄糖重吸收改变的代谢后果

期刊:Molecular Metabolism

影响因子:6.6

doi:10.1016/j.molmet.2025.102192

Ahmad Majdoleen, Permyakova Anna, Baraghithy Saja, Sahu Nilanjan, Abramovich Ifat, Agranovich Bella, Shalev Ori, Kogot-Levin Aviram, Nemirovski Alina, Gottlieb Eyal, Abramovitch Rinat, Leibowitz Gil, Hinden Liad, Tam Joseph

代谢

发表日期：2025

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Characterization of Neurensin-2 knockout mice: insights into stress-resilience mechanisms.

Neurensin-2 基因敲除小鼠的特征分析：对应激适应机制的深入了解

期刊:Translational Psychiatry

影响因子:6.2

doi:10.1038/s41398-025-03448-7

Hovav Hadas Catane, Kashi Ofer Yitzhak, Abu Ghanem Yumna, Stochinsky Naomi, Agbariya Laila, Yehuda Hila, Weitz-Aviv Moriya, Baraghithy Saja, Tam Joseph, Yaka Rami, Umschweif Gali

发表日期：2025

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Progressive endocannabinoid system dysregulation in autosomal dominant polycystic kidney disease

常染色体显性多囊肾病中内源性大麻素系统进行性失调

Endocannabinoid responses to relief of obstruction in acute injured kidney: a prospective observational study

急性肾损伤后内源性大麻素对梗阻解除的反应：一项前瞻性观察研究

Markedly Low Prevalence of Fatty Liver Despite Obesity in Prader-Willi Syndrome: A Search for Protective Genetic Markers

尽管普拉德-威利综合征患者肥胖，但脂肪肝患病率却显著偏低：寻找保护性遗传标记

Blockade of Interleukin-6 Trans-signaling in the Presence of Certain Gut Microbiota Induces Mature-onset Obesity in Mice

在特定肠道菌群存在的情况下阻断白细胞介素-6反式信号传导可诱导小鼠发生成年期肥胖

Hepatic CB1 receptor signaling triggers G(i/o)α-mediated lipolysis in lean mice but G(s)α-mediated lipogenesis in obese mice

肝脏CB1受体信号传导在瘦小鼠中触发G(i/o)α介导的脂肪分解，但在肥胖小鼠中触发G(s)α介导的脂肪生成。

Correction: Pharmaceutical targeting of the cannabinoid type 1 receptor impacts the crosstalk between immune cells and islets to reduce insulitis in humans

更正：药物靶向大麻素1型受体可影响免疫细胞与胰岛之间的相互作用，从而减轻人类胰岛炎。

Deep brain stimulation surgical timing, outcomes, and prognostic factors in patients with Parkinson's disease: A Chinese retrospective multicenter cohort study

帕金森病患者深部脑刺激手术时机、疗效及预后因素：一项中国回顾性多中心队列研究

Synthesis and Pharmacological Characterization of Novel Peripheral Cannabinoid-1 Receptor Blockers Based on a Tricyclic Scaffold

基于三环骨架的新型外周大麻素-1受体阻滞剂的合成及药理学表征

Metabolic consequences of altered kidney glucose reabsorption under normoglycemic conditions.

正常血糖条件下肾脏葡萄糖重吸收改变的代谢后果

Characterization of Neurensin-2 knockout mice: insights into stress-resilience mechanisms.

Neurensin-2 基因敲除小鼠的特征分析：对应激适应机制的深入了解