日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Activation of Gcn2 by small molecules designed to be inhibitors

通过设计为抑制剂的小分子激活 Gcn2

Kenneth R Carlson, Millie M Georgiadis, Feven Tameire, Kirk A Staschke, Ronald C Wek

ER Translocation of the MAPK Pathway Drives Therapy Resistance in BRAF-Mutant Melanoma

MAPK 通路的 ER 易位导致 BRAF 突变型黑色素瘤产生治疗耐药性

Rani Ojha, Nektaria M Leli, Angelique Onorati, Shengfu Piao, Ioannis I Verginadis, Feven Tameire, Vito W Rebecca, Cynthia I Chude, Sengottuvelan Murugan, Colin Fennelly, Estela Noguera-Ortega, Charleen T Chu, Shujing Liu, Xiaowei Xu, Clemens Krepler, Min Xiao, Wei Xu, Zhi Wei, Dennie T Frederick, Ge

ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression

ATF4 将 MYC 依赖的翻译活性与肿瘤进展过程中的生物能量需求结合起来

Feven Tameire, Ioannis I Verginadis, Nektaria Maria Leli, Christine Polte, Crystal S Conn, Rani Ojha, Carlo Salas Salinas, Frank Chinga, Alexandra M Monroy, Weixuan Fu, Paul Wang, Andrew Kossenkov, Jiangbin Ye, Ravi K Amaravadi, Zoya Ignatova, Serge Y Fuchs, J Alan Diehl, Davide Ruggero, Constantino

Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR

酸通过抑制 mTOR 暂停缺氧状态下的昼夜节律

Zandra E Walton, Chirag H Patel, Rebekah C Brooks, Yongjun Yu, Arig Ibrahim-Hashim, Malini Riddle, Alessandra Porcu, Tianying Jiang, Brett L Ecker, Feven Tameire, Constantinos Koumenis, Ashani T Weeraratna, David K Welsh, Robert Gillies, James C Alwine, Lin Zhang, Jonathan D Powell, Chi V Dang

A PERK-miR-211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival

PERK-miR-211 轴抑制昼夜节律调节剂和蛋白质合成以促进癌细胞存活

Yiwen Bu, Akihiro Yoshida, Nilesh Chitnis, Brian J Altman, Feven Tameire, Amanda Oran, Victoria Gennaro, Kent E Armeson, Steven B McMahon, Gerald B Wertheim, Chi V Dang, Davide Ruggero, Constantinos Koumenis, Serge Y Fuchs, J Alan Diehl

Development of a stress response therapy targeting aggressive prostate cancer

针对侵袭性前列腺癌的应激反应疗法研发

Nguyen, Hao G; Conn, Crystal S; Kye, Yae; Xue, Lingru; Forester, Craig M; Cowan, Janet E; Hsieh, Andrew C; Cunningham, John T; Truillet, Charles; Tameire, Feven; Evans, Michael J; Evans, Christopher P; Yang, Joy C; Hann, Byron; Koumenis, Constantinos; Walter, Peter; Carroll, Peter R; Ruggero, Davide

YAP1 enhances NF-κB-dependent and independent effects on clock-mediated unfolded protein responses and autophagy in sarcoma

YAP1 增强 NF-κB 对肉瘤中时钟介导的未折叠蛋白反应和自噬的依赖性和独立性影响

Adrian Rivera-Reyes, Shuai Ye, Gloria E Marino, Shaun Egolf, Gabrielle E Ciotti, Susan Chor, Ying Liu, Jessica M Posimo, Paul M C Park, Koreana Pak, Yael Babichev, Jaimarie Sostre-Colón, Feven Tameire, Nektaria Maria Leli, Constantinos Koumenis, Donita C Brady, Anthony Mancuso, Kristy Weber, Rebecca

Cell intrinsic and extrinsic activators of the unfolded protein response in cancer: Mechanisms and targets for therapy

癌细胞中未折叠蛋白反应的细胞内在和外在激活因子:机制和治疗靶点

Tameire, Feven; Verginadis, Ioannis I; Koumenis, Constantinos

De novo formation of insulin-producing "neo-β cell islets" from intestinal crypts

肠隐窝中胰岛素分泌“新生β细胞岛”的从头形成

Chen, Yi-Ju; Finkbeiner, Stacy R; Weinblatt, Daniel; Emmett, Matthew J; Tameire, Feven; Yousefi, Maryam; Yang, Chenghua; Maehr, Rene; Zhou, Qiao; Shemer, Ruth; Dor, Yuval; Li, Changhong; Spence, Jason R; Stanger, Ben Z

PERK-ing up autophagy during MYC-induced tumorigenesis

PERK激活MYC诱导的肿瘤发生过程中的自噬

Dey, Souvik; Tameire, Feven; Koumenis, Constantinos