USP15-modified ADMSCs-Exo alleviates chondrocyte damage and effectively relieved osteoarthritis by inducing M2 polarization of macrophages through deubiquitinating FOXC1.

USP15 修饰的 ADMSCs-Exo 通过去泛素化 FOXC1 诱导巨噬细胞 M2 极化，减轻软骨细胞损伤并有效缓解骨关节炎