日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Arsenic Trioxide and the MNK1 Inhibitor AUM001 Exert Synergistic Anti-Glioblastoma Effects by Modulating Key Translational, Cell Cycle, and Transmembrane Transport Pathways

三氧化二砷和MNK1抑制剂AUM001通过调节关键的翻译、细胞周期和跨膜转运途径发挥协同抗胶质母细胞瘤作用

Hao, Yue; Shaffer, Charles; Tang, Nanyun; DeLuca, Valerie; Baker, Angela; Berens, Michael E

Molecular profiling of glioblastoma-derived extracellular vesicles identifies small nucleolar RNAs as candidate liquid biomarkers for radiation- induced senescence.

对胶质母细胞瘤衍生的细胞外囊泡进行分子分析,发现小核仁 RNA 可作为辐射诱导衰老的候选液体生物标志物。

DeLuca Valerie, Hansen Nathaniel, Digumarti Priya, Tang Nanyun, Fink Karen, Snipes George, Pirrotte Patrick, Berens Michael

NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.

NK 细胞衍生的细胞外囊泡可增强非小细胞肺癌的细胞毒性和免疫细胞募集

Palade Joanna, Alsop Eric, Tang Nanyun, Antone Jerry, Paredes Dorothy M, Halder Tithi Ghosh, Soldi Raffaella, Bargenquast Taylor, Schwartz Gary, Finholt Jennifer, Snipes George J, Sharma Sunil, Berens Michael, Whitsett Timothy G, Van Keuren-Jensen Kendall, Kelly Ronan J

EXTH-38. Arsenic trioxide and the MNK1 inhibitor AUM001 exert synergistic anti-glioblastoma effects by modulating key translational, cell cycle, and transmembrane transport pathways

EXTH-38. 三氧化二砷和 MNK1 抑制剂 AUM001 通过调节关键的翻译、细胞周期和跨膜转运途径发挥协同抗胶质母细胞瘤作用

Chen, Xinpei; Zhou, Pengcheng; De, Luo; Li, Bo; Su, Song; Hao, Yue; Shaffer, Charles; Tang, Nanyun; Berens, Michael E

BIOM-37. EXTRACELLULAR VESICLES AS A PHARMACODYNAMIC REPORTER IN GLIOBLASTOMA

生物分子-37. 细胞外囊泡作为胶质母细胞瘤的药效学报告分子

Lin, Selena Y; Xia, Wei; Kim, Amy K; Chen, Dion; Schleyer, Shelby; Choi, Lin; Wang, Zhili; Hamilton, James P; Luu, Harry; Hann, Hie-Won; Chang, Ting-Tsung; Hu, Chi-Tan; Woodard, Abashai; Gade, Terence P; Su, Ying-Hsiu; DeLuca, Valerie; Tang, Nanyun; Hao, Yue; Raju, Anjali; Shaffer, Charles; Riviere-Cazaux, Cecile; Burns, Terry; Sarkaria, Jann; Parney, Ian; Pirotte, Patrick; Van Keuren-Jensen, Kendall; Berens, Michael

DIPG-47. DISCOVERING A MOLECULAR BASIS FOR VULNERABILITY OF H3K27M-DMG TO HISTONE DEACETYLASE INHIBITORS

DIPG-47. 发现 H3K27M-DMG 对组蛋白去乙酰化酶抑制剂易感性的分子基础

Hosahalli Vasanna, Smitha; Shah, Sonal D; Rohr, Bethany R; Roche, Breanne; Meyerson, Howard; Pateva, Irina; Paine, Danyelle; Hao, Yue; Tang, Nanyun; Biery, Matt; Vitanza, Nicholas; Berens, Michael

PTEN loss drives resistance to the neddylation inhibitor MLN4924 in glioblastoma and can be overcome with TOP2A inhibitors

PTEN 缺失会导致胶质母细胞瘤对 neddylation 抑制剂 MLN4924 产生耐药性,而 TOP2A 抑制剂可以克服这种耐药性。

Ferdosi, Shayesteh R; Taylor, Brett; Lee, Matthew; Tang, Nanyun; Peng, Sen; Bybee, Rita; Reid, George; Hartman, Lauren; Garcia-Mansfield, Krystine; Sharma, Ritin; Pirrotte, Patrick; Ma, Jianhui; Parisian, Alison D; Furnari, Frank; Dhruv, Harshil D; Berens, Michael E

High-throughput cell-based assays for identifying antagonists of multiple smoking-associated human nicotinic acetylcholine receptor subtypes

用于鉴定多种吸烟相关人类尼古丁乙酰胆碱受体亚型拮抗剂的高通量细胞检测方法

Kassner, Michelle; Eaton, J Brek; Tang, Nanyun; Petit, Joachim L; Meurice, Nathalie; Yin, Hongwei Holly; Whiteaker, Paul

Ponatinib Shows Potent Antitumor Activity in Small Cell Carcinoma of the Ovary Hypercalcemic Type (SCCOHT) through Multikinase Inhibition.

Ponatinib 通过多激酶抑制作用,在卵巢小细胞癌高钙血症型 (SCCOHT) 中显示出强大的抗肿瘤活性

Lang Jessica D, Hendricks William P D, Orlando Krystal A, Yin Hongwei, Kiefer Jeffrey, Ramos Pilar, Sharma Ritin, Pirrotte Patrick, Raupach Elizabeth A, Sereduk Chris, Tang Nanyun, Liang Winnie S, Washington Megan, Facista Salvatore J, Zismann Victoria L, Cousins Emily M, Major Michael B, Wang Yemin, Karnezis Anthony N, Sekulic Aleksandar, Hass Ralf, Vanderhyden Barbara C, Nair Praveen, Weissman Bernard E, Huntsman David G, Trent Jeffrey M

STAG2 is a clinically relevant tumor suppressor in pancreatic ductal adenocarcinoma

STAG2是胰腺导管腺癌中具有临床意义的肿瘤抑制基因。

Evers, Lisa; Perez-Mancera, Pedro A; Lenkiewicz, Elizabeth; Tang, Nanyun; Aust, Daniela; Knösel, Thomas; Rümmele, Petra; Holley, Tara; Kassner, Michelle; Aziz, Meraj; Ramanathan, Ramesh K; Von Hoff, Daniel D; Yin, Holly; Pilarsky, Christian; Barrett, Michael T