Transient intracellular expression of PD-L1 and VEGFR2 bispecific nanobody in cancer cells inspires long-term T cell activation and infiltration to combat tumor and inhibit cancer metastasis
癌细胞中PD-L1和VEGFR2双特异性纳米抗体的瞬时细胞内表达可激发T细胞的长期活化和浸润，从而对抗肿瘤并抑制癌症转移。
期刊:Molecular Cancer
影响因子:33.9
doi:10.1186/s12943-025-02253-6
Zhang, Lei; Lin, Yunfeng; Hu, Li; Wang, Yanan; Hu, Chaohua; Shangguan, Xinyi; Tang, Shuzhi; Chen, Jincan; Hu, Ping; Chen, Zhe-Sheng; Ke, Zun-Fu; Chen, Zhuo
肿瘤
T细胞
肿瘤免疫
EGF
PD-L1
EGFR
T细胞
细胞生物学
VEGF
免疫/内分泌
