Tang Wei-Jen相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Dimerization and dynamics of human angiotensin-I converting enzyme revealed by cryo-EM and MD simulations

冷冻电镜和分子动力学模拟揭示人血管紧张素I转化酶的二聚化和动力学

影响因子:6.4

doi:10.7554/eLife.106044

Mancl, Jordan M; Wu, Xiaoyang; Zhao, Minglei; Tang, Wei-Jen

发表日期：2025

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Characterization and modulation of human insulin degrading enzyme conformational dynamics to control enzyme activity

通过表征和调控人胰岛素降解酶的构象动力学来控制酶活性

doi:10.1101/2024.12.30.630732

Mancl, Jordan M; Liang, Wenguang G; Bayhi, Nicholas L; Wei, Hui; Budell, William; Mendez, Joshua H; Sosnick, Tobin R; Carragher, Bridget; Potter, Clinton S; Tang, Wei-Jen

免疫/内分泌

发表日期：2025

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Dimerization and dynamics of angiotensin-I converting enzyme revealed by cryo-EM and MD simulations

冷冻电镜和分子动力学模拟揭示血管紧张素I转化酶的二聚化和动力学

doi:10.1101/2025.01.09.632263

Mancl, Jordan M; Wu, Xiaoyang; Zhao, Minglei; Tang, Wei-Jen

发表日期：2025

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Degradation of Alzheimer's Amyloid-β by a Catalytically Inactive Insulin-Degrading Enzyme

催化活性缺失的胰岛素降解酶对阿尔茨海默病淀粉样蛋白β的降解

期刊:Journal of Molecular Biology

影响因子:4.5

doi:10.1016/j.jmb.2021.166993

Sahoo, Bikash R; Panda, Pritam Kumar; Liang, Wenguang; Tang, Wei-Jen; Ahuja, Rajeev; Ramamoorthy, Ayyalusamy

阿尔茨海默症

免疫/内分泌

发表日期：2021

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Pseudomonas aeruginosa exoenzyme Y directly bundles actin filaments

铜绿假单胞菌胞外酶Y直接束起肌动蛋白丝

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.RA119.012320

Mancl, Jordan M; Suarez, Cristian; Liang, Wenguang G; Kovar, David R; Tang, Wei-Jen

发表日期：2020

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Reinvestigating the synthesis and efficacy of small benzimidazole derivatives as presequence protease enhancers.

重新研究小分子苯并咪唑衍生物作为前导序列蛋白酶增强剂的合成和功效

期刊:European Journal of Medicinal Chemistry

影响因子:5.9

doi:10.1016/j.ejmech.2019.111746

Li Nan-Sheng, Liang Wenguang, Piccirilli Joseph A, Tang Wei-Jen

发表日期：2019

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Catalytic Mechanism of Amyloid-β Peptide Degradation by Insulin Degrading Enzyme: Insights from Quantum Mechanics and Molecular Mechanics Style Møller-Plesset Second Order Perturbation Theory Calculation

胰岛素降解酶催化β-淀粉样肽降解的机制：基于量子力学和分子力学的Møller-Plesset二阶微扰理论计算的启示

期刊:Journal of Chemical Information and Modeling

影响因子:5.3

doi:10.1021/acs.jcim.8b00406

Lai, Rui; Tang, Wei-Jen; Li, Hui

免疫/内分泌

发表日期：2018

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Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3.

CCL5 和 CCL3 寡聚化和糖胺聚糖结合的结构基础

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.1523981113

Liang Wenguang G, Triandafillou Catherine G, Huang Teng-Yi, Zulueta Medel Manuel L, Banerjee Shiladitya, Dinner Aaron R, Hung Shang-Cheng, Tang Wei-Jen

发表日期：2016

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Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme.

人类 CCL18、CCL3 和 CCL4 的结构揭示了四级结构和对胰岛素降解酶敏感性的分子决定因素

期刊:Journal of Molecular Biology

影响因子:4.5

doi:10.1016/j.jmb.2015.01.012

Liang Wenguang G, Ren Min, Zhao Fan, Tang Wei-Jen

免疫/内分泌

发表日期：2015

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Different Roles of N-Terminal and C-Terminal Domains in Calmodulin for Activation of Bacillus anthracis Edema Factor

钙调蛋白N端和C端结构域在激活炭疽芽孢杆菌水肿因子中发挥不同作用

doi:10.3390/toxins7072598

Lübker, Carolin; Dove, Stefan; Tang, Wei-Jen; Urbauer, Ramona J Bieber; Moskovitz, Jackob; Urbauer, Jeffrey L; Seifert, Roland

发表日期：2015

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