日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Efficient Preparation of Homogenous Antibody Conjugates via Glycosite-Specific Transglycosylation Enabled by Readily Available Glycosyl Donors

利用易得的糖基供体，通过糖基位点特异性转糖基化高效制备均一抗体偶联物

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.202518579
Cai, Deqin; Zhao, Yuan; Lu, Gaoyuan; Li, Chunrong; Lao, Yichong; Mudududdla, Ramesh; Zhang, Jiahao; Jia, Peijing; Huang, Penghsuan; Wu, Wenxin; Nguyen, Thao-Vy T; Huang, Xuhui; Li, Lingjun; Tang, Weiping
发表日期：2026
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Development of Prostate-Specific Lysosome-Targeting Degraders

前列腺特异性溶酶体靶向降解剂的开发

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.5c18594
Cai, Deqin; Chen, Xuankun; Zhou, Yaxian; Bio Idrissou, Malick; Hernandez, Reinier; Tang, Weiping
发表日期：2026
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Utilizing the HiBiT System to Identify CARM1 Degraders for Targeted Cancer Therapy

利用HiBiT系统鉴定CARM1降解剂用于靶向癌症治疗

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c01863
Bacabac, Megan; Hu, Mingshan; Liu, Fabao; Kim, Eui-Jun; Grkovic, Tanja; Kumar, Rohitesh; Akee, Rhone K; Hayes, Isaac; Mudududdla, Ramesh; Wang, Yidan; McGuire, Mason; Tang, Weiping; O'Keefe, Barry R; Bugni, Tim S; Xu, Wei
肿瘤
肿瘤免疫
CARM1
发表日期：2026
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Revealing the structure-activity relationship of Pt(1)/CeO(2) with (17)O solid-state NMR spectroscopy and DFT calculations

利用(17)O固态核磁共振波谱和DFT计算揭示Pt(1)/CeO(2)的结构-活性关系

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-58709-2
Wen, Yujie; Wang, Fang; Zhu, Jie; Wen, Qian; Xia, Xiaoli; Wen, Juan; Deng, Changshun; Du, Jia-Huan; Ke, Xiaokang; Zhang, Zhen; Guan, Hanxi; Nie, Lei; Wang, Meng; Hou, Wenhua; Li, Wei; Tang, Weiping; Ding, Weiping; Chen, Junchao; Peng, Luming
发表日期：2025
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Rh(II) and Chiral Phosphoric Acid Co-catalyzed Selective O-H Insertions for Stereodivergent O-Alkylation of Glycosides

Rh(II)和手性磷酸共催化选择性OH插入用于糖苷的立体发散O-烷基化

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.4c14614
Wu, Jicheng; Jia, Peijing; Tang, Hua; Cai, Deqin; Tang, Weiping
发表日期：2025
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Characterization of a dual degrader of MDM2 and GSPT1.

MDM2和GSPT1双重降解剂的特性分析

期刊:European Journal of Medicinal Chemistry
影响因子:5.9
doi:10.1016/j.ejmech.2025.117793
Tandon Ira, Esguerra Paulina N, Li Chunrong, Sun Huan, Yang Ka, Zhang Zhongrui, Peng Junmin, Tang Weiping
MDM2
发表日期：2025
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Development of a Partial Proteolysis Targeting Chimera Library Based on Achiral Cereblon E3 Ligase Ligands and its Application for Bruton's Tyrosine Kinase Degraders

基于非手性 Cereblon E3 连接酶配体的部分蛋白水解靶向嵌合体库的开发及其在布鲁顿酪氨酸激酶降解剂中的应用

期刊:ChemMedChem
影响因子:3.4
doi:10.1002/cmdc.202500209
Almodóvar-Rivera, Chelsi M; Tandon, Ira; Mudududdla, Ramesh; Esguerra, Paulina N; Lucio-Acero, Kevin; Tang, Weiping
信号转导
发表日期：2025
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Development of folate receptor targeting chimeras for cancer selective degradation of extracellular proteins

开发叶酸受体靶向嵌合体，用于癌细胞选择性降解细胞外蛋白

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-024-52685-9
Zhou, Yaxian; Li, Chunrong; Chen, Xuankun; Zhao, Yuan; Liao, Yaxian; Huang, Penghsuan; Wu, Wenxin; Nieto, Nicholas S; Li, Lingjun; Tang, Weiping
信号转导
细胞生物学
肿瘤
肿瘤免疫
发表日期：2024
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BCR::ABL1 Proteolysis-targeting chimeras (PROTACs): The new frontier in the treatment of Ph(+) leukemias?

BCR::ABL1蛋白水解靶向嵌合体（PROTACs）：Ph(+)白血病治疗的新前沿？

期刊:Leukemia
影响因子:13.4
doi:10.1038/s41375-024-02365-w
Cruz-Rodriguez, Nataly; Tang, Hua; Bateman, Benjamin; Tang, Weiping; Deininger, Michael
BCR
白血病
ABL1
发表日期：2024
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Non-Markovian Dynamic Models Identify Non-Canonical KRAS-VHL Encounter Complex Conformations for Novel PROTAC Design

非马尔可夫动态模型识别非典型 KRAS-VHL 遭遇复合物构象，用于新型 PROTAC 设计

期刊:JACS Au
影响因子:8.7
doi:10.1021/jacsau.4c00503
Qiu, Yunrui; Wiewiora, Rafal P; Izaguirre, Jesus A; Xu, Huafeng; Sherman, Woody; Tang, Weiping; Huang, Xuhui
RAS
VHL
发表日期：2024
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