OFD1 inhibition induces BRCAness to create a therapeutic vulnerability to PARP inhibition in pancreatic cancer.
OFD1 抑制诱导 BRCA 样改变，从而使胰腺癌对 PARP 抑制剂产生治疗敏感性
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-62295-8
Li Peng, Ye Junjie, Yang Qian, Wang Ni, Li Chaoyi, Zou Xiaoxiao, Luo Hanyan, Pan Yi, Jiang Lingxi, Shen Baiyong, Tang Zaiming, Zhong Qing
