日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A Novel Liver Cancer-Selective Histone Deacetylase Inhibitor Is Effective against Hepatocellular Carcinoma and Induces Durable Responses with Immunotherapy

一种新型肝癌选择性组蛋白去乙酰化酶抑制剂对肝细胞癌有效，并能诱导持久的免疫治疗反应。

期刊:ACS Pharmacology and Translational Science
影响因子:3.7
doi:10.1021/acsptsci.4c00358
Wu, Bocheng; Tapadar, Subhasish; Ruan, Zhiping; Sun, Carrie Q; Arnold, Rebecca S; Johnston, Alexis; Olugbami, Jeremiah O; Arunsi, Uche; Gaul, David A; Petros, John A; Kobayashi, Tatsuya; Duda, Dan G; Oyelere, Adegboyega K
肿瘤
表观遗传
肿瘤免疫
肝癌
乙酰化
细胞生物学
免疫/内分泌
发表日期：2024
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Development and validation of a sensitive LC-MS/MS assay of GT-14, a novel Gα(i)2 inhibitor, in rat plasma, and its application in pharmacokinetic study

建立并验证了一种灵敏的液相色谱-串联质谱（LC-MS/MS）检测方法，用于测定大鼠血浆中新型Gα(i)2抑制剂GT-14的浓度，并将其应用于药代动力学研究。

期刊:Journal of Pharmaceutical and Biomedical Analysis
影响因子:3.1
doi:10.1016/j.jpba.2024.116183
Sarkar, Mahua; Ma, Jing; Tapadar, Subhasish; Caggia, Silvia; Oyelere, Adegboyega K; Khan, Shafiq A; Xie, Huan
Rat
多发性硬化症
发表日期：2024
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Presence of Bromotyrosine Alkaloids in Marine Sponges Is Independent of Metabolomic and Microbiome Architectures

海洋海绵中溴酪氨酸生物碱的存在与代谢组和微生物组结构无关

期刊:mSystems
影响因子:4.6
doi:10.1128/mSystems.01387-20
Mohanty, Ipsita; Tapadar, Subhasish; Moore, Samuel G; Biggs, Jason S; Freeman, Christopher J; Gaul, David A; Garg, Neha; Agarwal, Vinayak
微生物学
代谢
发表日期：2021
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Deferiprone: Pan-selective Histone Lysine Demethylase Inhibition Activity and Structure Activity Relationship Study

去铁酮：泛选择性组蛋白赖氨酸去甲基酶抑制活性及构效关系研究

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-019-39214-1
Khodaverdian, Verjine; Tapadar, Subhasish; MacDonald, Ian A; Xu, Yuan; Ho, Po-Yi; Bridges, Allison; Rajpurohit, Pragya; Sanghani, Bhakti A; Fan, Yuhong; Thangaraju, Muthusamy; Hathaway, Nathaniel A; Oyelere, Adegboyega K
发表日期：2019
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Publisher Correction: Inhibition of TBK1/IKKε Promotes Regeneration of Pancreatic β-cells

出版商更正：TBK1/IKKε抑制剂促进胰岛β细胞再生

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-019-54301-z
Xu, Jin; Jia, Yun-Fang; Tapadar, Subhasish; Weaver, Jessica D; Raji, Idris O; Pithadia, Deeti J; Javeed, Naureen; García, Andrés J; Choi, Doo-Sup; Matveyenko, Aleksey V; Oyelere, Adegboyega K; Shin, Chong Hyun
细胞生物学
TBK1
发表日期：2019
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Inhibition of TBK1/IKKε Promotes Regeneration of Pancreatic β-cells

抑制TBK1/IKKε可促进胰岛β细胞再生

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-018-33875-0
Xu, Jin; Jia, Yun-Fang; Tapadar, Subhasish; Weaver, Jessica D; Raji, Idris O; Pithadia, Deeti J; Javeed, Naureen; García, Andrés J; Choi, Doo-Sup; Matveyenko, Aleksey V; Oyelere, Adegboyega K; Shin, Chong Hyun
细胞生物学
TBK1
发表日期：2018
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Novel Selective Calpain 1 Inhibitors as Potential Therapeutics in Alzheimer's Disease

新型选择性钙蛋白酶1抑制剂作为阿尔茨海默病潜在治疗药物

期刊:Journal of Alzheimers Disease
影响因子:3.1
doi:10.3233/JAD-150618
Fà, Mauro; Zhang, Hong; Staniszewski, Agnieszka; Saeed, Faisal; Shen, Li W; Schiefer, Isaac T; Siklos, Marton I; Tapadar, Subhasish; Litosh, Vladislav A; Libien, Jenny; Petukhov, Pavel A; Teich, Andrew F; Thatcher, Gregory R J; Arancio, Ottavio
阿尔茨海默症
发表日期：2016
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Exploiting translational stalling peptides in an effort to extend azithromycin interaction within the prokaryotic ribosome nascent peptide exit tunnel.

利用翻译停滞肽来延长阿奇霉素在原核生物核糖体新生肽出口通道内的相互作用

期刊:Bioorganic & Medicinal Chemistry
影响因子:3
doi:10.1016/j.bmc.2015.04.078
Washington Arren Z, Tapadar Subhasish, George Alex, Oyelere Adegboyega K
其它
发表日期：2015
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Isoxazole moiety in the linker region of HDAC inhibitors adjacent to the Zn-chelating group: effects on HDAC biology and antiproliferative activity

HDAC抑制剂连接区中与锌螯合基团相邻的异噁唑部分：对HDAC生物学和抗增殖活性的影响

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2009.04.058
Tapadar, Subhasish; He, Rong; Luchini, Doris N; Billadeau, Daniel D; Kozikowski, Alan P
发表日期：2009
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Use of the nitrile oxide cycloaddition (NOC) reaction for molecular probe generation: a new class of enzyme selective histone deacetylase inhibitors (HDACIs) showing picomolar activity at HDAC6

利用腈氧化物环加成 (NOC) 反应生成分子探针：一类新型酶选择性组蛋白去乙酰化酶抑制剂 (HDACI)，对 HDAC6 表现出皮摩尔级活性。

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm8002894
Kozikowski, Alan P; Tapadar, Subhasish; Luchini, Doris N; Kim, Ki Hwan; Billadeau, Daniel D
乙酰化
表观遗传
HDAC6
发表日期：2008
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