文献库，生知库 | 链接生命科学的每一步

日期影响因子

Protein Kinase Inhibitors and Oxidative Stress Modulate In Vivo Phosphorylation of Trypanosoma cruzi DNA Polymerase β

蛋白激酶抑制剂和氧化应激调节克氏锥虫DNA聚合酶β的体内磷酸化

期刊:Pharmaceutics

影响因子:5.5

doi:10.3390/pharmaceutics18030385

Maldonado, Edio; Oyarce, Matías; Canobra, Paz; Rojas, Emilia; Urbina, Fabiola; Tapia, Julio C; Jara, Lilian; Miralles, Vicente J; Castillo, Christian; Solari, Aldo

发表日期：2026

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Modeling Chronic BaP Exposure in Bronchial Epithelial Cells Reveals Multi-Scale Drivers of Early Preneoplastic Reprogramming.

模拟支气管上皮细胞中慢性 BaP 暴露揭示早期癌前重编程的多尺度驱动因素。

影响因子:5.2

doi:10.3390/cells15060566

Andrade-Madrigal Cristian, Rojas-Fuentes Cecilia, DÃaz-Mijares Javier, Calaf Gloria M, Santoro Pablo M, CorvalÃ¡n Alejandro H, Medina Francisca J, Torres Cristian G, Romero-Vicencio Paula, Tapia Julio C, Acevedo MÃ³nica L, Soto-Rifo Ricardo, Boccardo Enrique, Aguayo Francisco

细胞生物学

发表日期：2026

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The miR-146a Single Nucleotide Polymorphism rs2910164 Promotes Proliferation, Chemoresistance, Migration, Invasion, and Apoptosis Suppression in Breast Cancer Cells.

miR-146a 单核苷酸多态性 rs2910164 促进乳腺癌细胞增殖、化疗耐药、迁移、侵袭和凋亡抑制

影响因子:5.2

doi:10.3390/cells14080612

Morales-GonzÃ¡lez Sarai, Calaf Gloria M, AcuÃ±a MÃ³nica, Tapia Julio C, Jara Lilian

细胞生物学

发表日期：2025

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The Role of Xenobiotics and Anelloviruses in Colorectal Cancer: Mechanisms and Perspectives

异生物质和环状病毒在结直肠癌中的作用：机制和展望

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms26094354

Aguayo, Francisco; Tapia, Julio C; Calaf, Gloria M; Muñoz, Juan P; Osorio, Julio C; Guzmán-Venegas, Matías; Moreno-León, Carolina; Levican, Jorge; Andrade-Madrigal, Cristian

发表日期：2025

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Decreased Endothelin-1 bioavailability impairs aggressiveness of gallbladder cancer cells.

内皮素-1生物利用度降低会削弱胆囊癌细胞的侵袭性

期刊:Biological Research

影响因子:4.6

doi:10.1186/s40659-025-00637-y

Vidal-Vidal Jetzabel, Brown-Brown David, Quilaqueo-Millaqueo Nelson, PeÃ±a-MÃ¼nzenmayer Gaspar, Spichiger Carlos, Quezada-MonrÃ¡s Claudia, Salazar-Onfray Flavio, Tapia Julio C, Niechi Ignacio

细胞生物学

发表日期：2025

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Cisplatin-resistance and aggressiveness are enhanced by a highly stable endothelin-converting enzyme-1c in lung cancer cells

肺癌细胞中高度稳定的内皮素转化酶-1c可增强顺铂耐药性和侵袭性。

期刊:Biological Research

影响因子:4.6

doi:10.1186/s40659-024-00551-9

Almarza, Cristopher; Villalobos-Nova, Karla; Toro, María A; González, Manuel; Niechi, Ignacio; Brown-Brown, David A; López-Muñoz, Rodrigo A; Silva-Pavez, Eduardo; Gaete-Ramírez, Belén; Varas-Godoy, Manuel; Burzio, Verónica A; Jara, Lilian; Aguayo, Francisco; Tapia, Julio C

细胞生物学

发表日期：2024

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In Vitro Identification of Phosphorylation Sites on TcPolβ by Protein Kinases TcCK1, TcCK2, TcAUK1, and TcPKC1 and Effect of Phorbol Ester on Activation by TcPKC of TcPolβ in Trypanosoma cruzi Epimastigotes

体外鉴定蛋白激酶TcCK1、TcCK2、TcAUK1和TcPKC1对TcPolβ的磷酸化位点，以及佛波酯对克氏锥虫表鞭毛体中TcPKC激活TcPolβ的影响

期刊:Microorganisms

影响因子:4.2

doi:10.3390/microorganisms12050907

Maldonado, Edio; Canobra, Paz; Oyarce, Matías; Urbina, Fabiola; Miralles, Vicente J; Tapia, Julio C; Castillo, Christian; Solari, Aldo

发表日期：2024

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Association of Germline Variation in Driver Genes with Breast Cancer Risk in Chilean Population

智利人群中驱动基因种系变异与乳腺癌风险的关联

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms242216076

Morales-Pison, Sebastián; Tapia, Julio C; Morales-González, Sarai; Maldonado, Edio; Acuña, Mónica; Calaf, Gloria M; Jara, Lilian

发表日期：2023

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Association of FANCM Mutations with Familial and Early-Onset Breast Cancer Risk in a South American Population

FANCM基因突变与南美人群家族性和早发性乳腺癌风险的关联

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms24044041

Morales-Pison, Sebastian; Morales-González, Sarai; Fernandez-Ramires, Ricardo; Tapia, Julio C; Maldonado, Edio; Calaf, Gloria M; Jara, Lilian

发表日期：2023

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A Single Variant in Pri-miRNA-155 Associated with Susceptibility to Hereditary Breast Cancer Promotes Aggressiveness in Breast Cancer Cells

Pri-miRNA-155 中的一个单一变异与遗传性乳腺癌的易感性相关，并促进乳腺癌细胞的侵袭性。

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms232315418

Landeros, Natalia; Gonzalez-Hormazabal, Patricio; Pérez-Moreno, Pablo; Tapia, Julio C; Jara, Lilian

细胞生物学

发表日期：2022

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