Tarcic相关文献与解析，生知库 | 链接生命科学的每一步

Lan, Yan; Yeung, Tsz-Lun; Huang, Hui; Wegener, Ansgar A; Saha, Somdutta; Toister-Achituv, Mira; Jenkins, Molly H; Chiu, Li-Ya; Lazorchak, Adam; Tarcic, Ohad; Wang, Hong; Qi, Jin; Locke, George; Kalimi, Doron; Qin, Guozhong; Marelli, Bo; Yu, Huakui; Gross, Alec W; Derner, Melissa G; Soloviev, Maria; Botte, Mathieu; Sircar, Aroop; Ma, Hong; Sood, Vanita D; Zhang, Dong; Jiang, Feng; Lo, Kin-Ming

PD-L1

肿瘤

TGF-β

肿瘤免疫

发表日期：2022

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Clinical and Functional Characterization of Atypical KRAS/NRAS Mutations in Metastatic Colorectal Cancer

转移性结直肠癌中非典型KRAS/NRAS突变的临床和功能特征

期刊:Clinical Cancer Research

影响因子:10.2

doi:10.1158/1078-0432.CCR-21-0180

Loree, Jonathan M; Wang, Yucai; Syed, Muddassir A; Sorokin, Alexey V; Coker, Oluwadara; Xiu, Joanne; Weinberg, Benjamin A; Vanderwalde, Ari M; Tesfaye, Anteneh; Raymond, Victoria M; Miron, Benjamin; Tarcic, Gabi; Zelichov, Ori; Broaddus, Russell R; Ng, Patrick Kwok Shing; Jeong, Kang Jin; Tsang, Yiu Huen; Mills, Gordon B; Overman, Michael J; Grothey, Axel; Marshall, John L; Kopetz, Scott

gRNA Sequence Heterology Tolerance Catalyzed by CRISPR/Cas in an In Vitro Homology-Directed Repair Reaction

CRISPR/Cas在体外同源定向修复反应中催化gRNA序列异质性耐受

期刊:Molecular Therapy-Nucleic Acids

影响因子:6.1

doi:10.1016/j.omtn.2020.03.012

Hewes, Amanda M; Sansbury, Brett M; Barth, Shaul; Tarcic, Gabi; Kmiec, Eric B

发表日期：2020

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A Novel System for Functional Determination of Variants of Uncertain Significance using Deep Convolutional Neural Networks

一种利用深度卷积神经网络对意义不明确的变异进行功能确定的新系统

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-020-61173-1

Lior Zimmerman, Ori Zelichov, Arie Aizenmann, Zohar Barbash, Michael Vidne, Gabi Tarcic

神经

发表日期：2020

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Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers

突变 p53 功能增强是结直肠癌干细胞标志物高表达水平的基础

期刊:Oncogene

影响因子:6.9

doi:10.1038/s41388-017-0060-8

Hilla Solomon, Nathan Dinowitz, Ioannis S Pateras, Tomer Cooks, Yoav Shetzer, Alina Molchadsky, Meital Charni, Stav Rabani, Gabriela Koifman, Ohad Tarcic, Ziv Porat, Ira Kogan-Sakin, Naomi Goldfinger, Moshe Oren, Curtis C Harris, Vassilis G Gorgoulis, Varda Rotter

Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers

突变型p53获得功能是结直肠癌干细胞标志物高表达的根本原因。

期刊:

影响因子:6.9

doi:PMC6448595

Hilla Solomon，Nathan Dinowitz，Ioannis S Pateras，Tomer Cooks，Yoav Shetzer，Alina Molchadsky，Meital Charni，Stav Rabani，Gabriela Koifman，Ohad Tarcic，Ziv Porat，Ira Kogan-Sakin，Naomi Goldfinger，Moshe Oren，Curtis C Harris，Vassilis G Gorgoulis，Varda Rotter

Revisited analysis of a SHIVA01 trial cohort using functional mutational analyses successfully predicted treatment outcome

使用功能突变分析对 SHIVA01 试验队列进行重新分析，成功预测了治疗结果

期刊:Molecular Oncology

影响因子:5

doi:10.1002/1878-0261.12180

Maud Kamal, Gabi Tarcic, Sylvain Dureau, Oded Edelheit, Zohar Barbash, Charlotte Lecerf, Claire Morel, Benjamin Miron, Celine Callens, Nicolas Servant, Ivan Bieche, Michael Vidne, Christophe Le Tourneau

CRISPR-Directed In Vitro Gene Editing of Plasmid DNA Catalyzed by Cpf1 (Cas12a) Nuclease and a Mammalian Cell-Free Extract

利用 Cpf1 (Cas12a) 核酸酶和哺乳动物无细胞提取物催化的 CRISPR 指导的质粒 DNA 体外基因编辑

期刊:CRISPR Journal

影响因子:3.7

doi:10.1089/crispr.2018.0006.

Brett M Sansbury,Amanda M Wagner,Erez Nitzan,Gabi Tarcic,Eric B Kmiec

细胞生物学

发表日期：2018

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SILAC identifies LAD1 as a filamin-binding regulator of actin dynamics in response to EGF and a marker of aggressive breast tumors

SILAC 发现 LAD1 是响应 EGF 的肌动蛋白动力学的细丝蛋白结合调节剂，也是侵袭性乳腺肿瘤的标志物

期刊:Science Signaling

影响因子:

doi:10.1126/scisignal.aan0949

Lee Roth, Swati Srivastava, Moshit Lindzen, Aldema Sas-Chen, Michal Sheffer, Mattia Lauriola, Yehoshua Enuka, Ashish Noronha, Maicol Mancini, Sara Lavi, Gabi Tarcic, Gur Pines, Nava Nevo, Ori Heyman, Tamar Ziv, Oscar M Rueda, Davide Gnocchi, Eli Pikarsky, Arie Admon, Carlos Caldas, Yosef Yarden

RNF20 and histone H2B ubiquitylation exert opposing effects in Basal-Like versus luminal breast cancer

RNF20 和组蛋白 H2B 泛素化在基底样乳腺癌和管腔乳腺癌中发挥相反的作用

期刊:Cell Death and Differentiation

影响因子:13.7

doi:10.1038/cdd.2016.126

Ohad Tarcic, Roy Z Granit, Ioannis S Pateras, Hadas Masury, Bella Maly, Yaara Zwang, Yosef Yarden, Vassilis G Gorgoulis, Eli Pikarsky, Ittai Ben-Porath, Moshe Oren

Colocalized targeting of TGF-β and PD-L1 by bintrafusp alfa elicits distinct antitumor responses

bintrafusp alfa 对 TGF-β 和 PD-L1 的共定位靶向作用可诱导不同的抗肿瘤反应

Clinical and Functional Characterization of Atypical KRAS/NRAS Mutations in Metastatic Colorectal Cancer

转移性结直肠癌中非典型KRAS/NRAS突变的临床和功能特征

gRNA Sequence Heterology Tolerance Catalyzed by CRISPR/Cas in an In Vitro Homology-Directed Repair Reaction

CRISPR/Cas在体外同源定向修复反应中催化gRNA序列异质性耐受

A Novel System for Functional Determination of Variants of Uncertain Significance using Deep Convolutional Neural Networks

一种利用深度卷积神经网络对意义不明确的变异进行功能确定的新系统

Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers

突变 p53 功能增强是结直肠癌干细胞标志物高表达水平的基础

Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers

突变型p53获得功能是结直肠癌干细胞标志物高表达的根本原因。

Revisited analysis of a SHIVA01 trial cohort using functional mutational analyses successfully predicted treatment outcome

使用功能突变分析对 SHIVA01 试验队列进行重新分析，成功预测了治疗结果

CRISPR-Directed In Vitro Gene Editing of Plasmid DNA Catalyzed by Cpf1 (Cas12a) Nuclease and a Mammalian Cell-Free Extract

利用 Cpf1 (Cas12a) 核酸酶和哺乳动物无细胞提取物催化的 CRISPR 指导的质粒 DNA 体外基因编辑

SILAC identifies LAD1 as a filamin-binding regulator of actin dynamics in response to EGF and a marker of aggressive breast tumors

SILAC 发现 LAD1 是响应 EGF 的肌动蛋白动力学的细丝蛋白结合调节剂，也是侵袭性乳腺肿瘤的标志物

RNF20 and histone H2B ubiquitylation exert opposing effects in Basal-Like versus luminal breast cancer

RNF20 和组蛋白 H2B 泛素化在基底样乳腺癌和管腔乳腺癌中发挥相反的作用