Pitx1 haploinsufficiency causes clubfoot in humans and a clubfoot-like phenotype in mice
Pitx1单倍体不足会导致人类患上先天性马蹄内翻足,并在小鼠中引起类似马蹄内翻足的表型。
期刊:Human Molecular Genetics
影响因子:3.2
doi:10.1093/hmg/ddr313
Alvarado, David M; McCall, Kevin; Aferol, Hyuliya; Silva, Matthew J; Garbow, Joel R; Spees, William M; Patel, Tarpit; Siegel, Marilyn; Dobbs, Matthew B; Gurnett, Christina A