Off-Target Inhibition of Human Dihydroorotate Dehydrogenase (hDHODH) Highlights Challenges in the Development of Fat Mass and Obesity-Associated Protein (FTO) Inhibitors.
人类二氢乳清酸脱氢酶 (hDHODH) 的脱靶抑制凸显了脂肪量和肥胖相关蛋白 (FTO) 抑制剂开发中的挑战
期刊:ACS Pharmacology and Translational Science
影响因子:3.7
doi:10.1021/acsptsci.4c00533
Tarullo Marco, Fernandez Rodriguez Guillermo, Iaiza Alessia, Venezia Sara, Macone Alberto, Incocciati Alessio, Masciarelli Silvia, Marchioni Marcella, Giorgis Marta, Lolli Marco Lucio, Fornaseri Federico, Proietti Ludovica, Grebien Florian, Rosignoli Serena, Paiardini Alessandro, Rotili Dante, Mai Antonello, Bochenkova Elena, Caflisch Amedeo, Fazi Francesco, Fatica Alessandro
