日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structures of the 26 S proteasome in complex with the Hsp70 co-chaperone Bag1 reveal a mechanism for direct substrate transfer

26S蛋白酶体与Hsp70辅助伴侣蛋白Bag1复合物的结构揭示了一种直接底物转移的机制

Moisés Maestro-López,Tat Cheung Cheng,Jimena Muntaner,Margarita Menéndez,Melissa Alonso,Andreas Schweitzer,Masato Ishizaka,Robert J Tomko Jr,Jorge Cuéllar,José María Valpuesta,Eri Sakata

The vacuolar tauopathy-associated mutation D395G confers redox sensitivity to p97/VCP

空泡性tau蛋白病相关突变D395G赋予p97/VCP氧化还原敏感性

Rout, Smruti R; Kulke, Martin; Droemer, Maxim A; Wendel, Marcel; Cheng, Tat Cheung; Mauck, Tristan A; Asgari, Sean; Nemec, Antonia A; Shein, Mikhail; Sato, Yusuke; Fukai, Shuya; Witte, Gregor; Tomko, Robert J; Stengel, Florian; Zacharias, Martin; Schuetz, Anne K; Sakata, Eri

Characterizing ATP processing by the AAA+ protein p97 at the atomic level

在原子水平上表征 AAA+ 蛋白 p97 的 ATP 处理

Mikhail Shein #, Manuel Hitzenberger #, Tat Cheung Cheng #, Smruti R Rout, Kira D Leitl, Yusuke Sato, Martin Zacharias, Eri Sakata, Anne K Schütz5

Structural basis for safe and efficient energy conversion in a respiratory supercomplex

呼吸超级复合物中安全高效能量转换的结构基础

Wei-Chun Kao, Claire Ortmann de Percin Northumberland, Tat Cheung Cheng, Julio Ortiz, Alexandre Durand, Ottilie von Loeffelholz, Oliver Schilling, Martin L Biniossek, Bruno P Klaholz, Carola Hunte

Implementation of evidence on management of pleural diseases: insights from a territory-wide survey of clinicians in Hong Kong

香港全港临床医生调查中关于胸膜疾病管理循证实践的启示

Lui, Macy M S; Yeung, Yiu-Cheong; Ngai, Jenny C L; Sin, Kit-Man; Lo, Yi-Tat; Cheung, Alice P S; Chiang, Ka-Yan; Chan, Yu-Hong; Chan, Ken K P; Lam, Connie H K; Law, Wei-Lam; Fung, Siu-Leung; Lam, Wai-Kei; Lam, David C L; Shek, Lam-Hin; Wong, Ida W Y; Yau, Anthony P Y; Lee, Yun-Chor Gary; Chan, Johnny W M

Transposon molecular domestication and the evolution of the RAG recombinase.

转座子分子驯化和RAG重组酶的进化

Zhang Yuhang, Cheng Tat Cheung, Huang Guangrui, Lu Qingyi, Surleac Marius D, Mandell Jeffrey D, Pontarotti Pierre, Petrescu Andrei J, Xu Anlong, Xiong Yong, Schatz David G

Structural basis of antagonism of human APOBEC3F by HIV-1 Vif

HIV-1 Vif拮抗人APOBEC3F的结构基础

Hu, Yingxia; Desimmie, Belete A; Nguyen, Henry C; Ziegler, Samantha J; Cheng, Tat Cheung; Chen, John; Wang, Jia; Wang, Hongwei; Zhang, Kai; Pathak, Vinay K; Xiong, Yong

A Near-Atomic Structure of the Dark Apoptosome Provides Insight into Assembly and Activation

暗凋亡小体的近原子结构揭示了其组装和激活机制

Cheng, Tat Cheung; Akey, Ildikó V; Yuan, Shujun; Yu, Zhiheng; Ludtke, Steven J; Akey, Christopher W

A near atomic structure of the active human apoptosome

活性人凋亡体的近原子结构

Cheng, Tat Cheung; Hong, Chuan; Akey, Ildikó V; Yuan, Shujun; Akey, Christopher W

Structural mechanism of ligand activation in human calcium-sensing receptor

人类钙敏感受体配体激活的结构机制

Geng, Yong; Mosyak, Lidia; Kurinov, Igor; Zuo, Hao; Sturchler, Emmanuel; Cheng, Tat Cheung; Subramanyam, Prakash; Brown, Alice P; Brennan, Sarah C; Mun, Hee-Chang; Bush, Martin; Chen, Yan; Nguyen, Trang X; Cao, Baohua; Chang, Donald D; Quick, Matthias; Conigrave, Arthur D; Colecraft, Henry M; McDonald, Patricia; Fan, Qing R