日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Structure and activation of the Drosophila insulin receptor by three Drosophila insulin-like peptides

三种果蝇胰岛素样肽对果蝇胰岛素受体的结构和激活作用

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-64586-6
Cai, Kai; Ng, Michelle; Yamamoto, Rochele R; Hossain, Mohammed Akhter; Hall, Catherine; Wade, John D; Tatar, Marc; Choi, Eunhee; Bai, Xiao-Chen
Drosophila
信号转导
免疫/内分泌
发表日期：2025
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Keap1-independent Nrf2 regulation: A novel therapeutic target for treating kidney disease

Keap1非依赖性Nrf2调控：治疗肾脏疾病的新靶点

期刊:Redox Biology
影响因子:11.9
doi:10.1016/j.redox.2025.103593
Zhang, Jiahui; Zhang, Mingzhuo; Tatar, Marc; Gong, Rujun
信号转导
发表日期：2025
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Glycogen synthase kinase 3β: a key player in progressive chronic kidney disease

糖原合成酶激酶3β：进行性慢性肾脏病中的关键因素

期刊:Clinical Science
影响因子:7.7
doi:10.1042/CS20245219
Zhang, Mingzhuo; Tatar, Marc; Gong, Rujun
信号转导
发表日期：2025
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Mutation in IR or IGF1R produces features of long-lived mice while maintaining metabolic health

IR或IGF1R基因突变可使小鼠表现出长寿的特征，同时维持其代谢健康。

期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.189683
Hernández-Arciga, Ulalume; Kim, Jun Kyoung; Fisher, Jacob L; Tyshkovskiy, Alexander; Moldakozhayev, Alibek; Hall, Catherine; Ghosh, Souvik; Govindaraj, Yashvandhini; Sipula, Ian J; Kastroll, Jake; Cooke, Diana; Luo, Jinping; Alder, Jonathan K; Rizzo, Stacey J Sukoff; Ables, Gene P; Choi, Eunhee; Gladyshev, Vadim N; Jurczak, Michael J; Tatar, Marc; Parkhitko, Andrey A
IGF1
代谢
发表日期：2025
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An insulin-sensitive Drosophila insulin-like receptor mutant remodels methionine metabolism to extend lifespan

一种对胰岛素敏感的果蝇胰岛素样受体突变体通过重塑蛋氨酸代谢来延长寿命

期刊:PLoS Genetics
影响因子:3.7
doi:10.1371/journal.pgen.1011640
Tatar, Marc; Zheng, Wenjing; Yadav, Shweta; Yamamoto, Rochele; Curtis-Joseph, Noelle; Li, Shengxi; Wang, Lin; Parkhitko, Andrey A
代谢
信号转导
Drosophila
免疫/内分泌
发表日期：2025
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Mutation of an insulin-sensitive Drosophila insulin-like receptor mutant requires methionine metabolism reprogramming to extend lifespan

果蝇胰岛素样受体突变体对胰岛素敏感，其突变需要蛋氨酸代谢重编程才能延长寿命

期刊:
影响因子:
doi:10.1101/2025.02.28.640731
Tatar, Marc; Zheng, Wenjing; Yadav, Shweta; Yamamoto, Rochele; Curtis-Joseph, Noelle; Li, Shengxi; Wang, Lin; Parkhitko, Andrey A
Drosophila
信号转导
代谢
代谢重编程
免疫/内分泌
发表日期：2025
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Combinatorial interventions in aging

老年综合干预措施

期刊:Nature Aging
影响因子:19.4
doi:10.1038/s43587-023-00489-9
Parkhitko, Andrey A; Filine, Elizabeth; Tatar, Marc
发表日期：2023
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Stalking the link between reproduction and aging: After decades of research, it still remains a mystery whether and how reproduction drives the process of aging: After decades of research, it still remains a mystery whether and how reproduction drives the process of aging

探究生育与衰老之间的联系：经过数十年的研究，生育是否以及如何驱动衰老过程仍然是个谜。

期刊:EMBO Reports
影响因子:6.2
doi:10.15252/embr.202357374
Tatar, Marc
衰老
发表日期：2023
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Aging modulated by the Drosophila insulin receptor through distinct structure-defined mechanisms

果蝇胰岛素受体通过独特的结构定义机制调节衰老。

期刊:Genetics
影响因子:5.1
doi:10.1093/genetics/iyaa037
Yamamoto, Rochele; Palmer, Michael; Koski, Helen; Curtis-Joseph, Noelle; Tatar, Marc
Drosophila
信号转导
衰老
免疫/内分泌
发表日期：2021
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Aging Regulated Through a Stability Model of Insulin/Insulin Growth Factor Receptor Function

衰老调控是通过胰岛素/胰岛素样生长因子受体功能的稳定性模型实现的

期刊:Frontiers in Endocrinology
影响因子:4.6
doi:10.3389/fendo.2021.649880
Tatar, Marc
信号转导
衰老
免疫/内分泌
发表日期：2021
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