日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Fosmanogepix for the Treatment of Invasive Mold Diseases Caused by Aspergillus Species and Rare Molds: A Phase 2, Open-Label Study (AEGIS)

Fosmanogepix 用于治疗由曲霉菌和罕见霉菌引起的侵袭性霉菌病：一项 2 期开放标签研究 (AEGIS)

期刊:Clinical Infectious Diseases
影响因子:7.3
doi:10.1093/cid/ciaf185
Hodges, Michael R; Tawadrous, Margaret; Cornely, Oliver A; Thompson, George R; Slavin, Monica A; Maertens, Johan A; Dadwal, Sanjeet S; Rahav, Galia; Hazel, Susan; Almas, Mary; Jakate, Abhijeet; Pypstra, Rienk
发表日期：2025
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Endurance training increases a ubiquitylated form of histone H3 in the skeletal muscle, supporting Notch1 upregulation in an MDM2-dependent manner

耐力训练会增加骨骼肌中组蛋白H3的泛素化形式，从而以MDM2依赖的方式促进Notch1的上调。

期刊:Journal of Physiology-London
影响因子:4.4
doi:10.1113/JP288947
Lam, Brian; Gulri, Manpreet; Akhtar, Sokaina; Lemieux, Pierre; Tawadrous, Monica; Murugathasan, Mayoorey; Abdul-Sater, Ali A; Roudier, Emilie
表观遗传
Notch
MDM2
泛素化
Notch1
发表日期：2025
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Pharmacokinetics and Safety of Ceftazidime-Avibactam in Neonates and Young Infants: A Phase 2a, Multicenter Prospective Trial

头孢他啶-阿维巴坦在新生儿和婴幼儿中的药代动力学和安全性：一项 2a 期多中心前瞻性试验

期刊:Journal of the Pediatric Infectious Diseases Society
影响因子:2.6
doi:10.1093/jpids/piaf028
Bradley, John; Roilides, Emmanuel; Tawadrous, Margaret; Yan, Jean Li; Soto, Elena; Stone, Gregory G; Kamat, Shweta; Irani, Paurus; England, Richard
发表日期：2025
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Hospitalization Following Outpatient Diagnosis of Respiratory Syncytial Virus in Adults

成人呼吸道合胞病毒门诊诊断后住院治疗

期刊:Jama Network Open
影响因子:9.7
doi:10.1001/jamanetworkopen.2024.46010
Landi, Suzanne N; Garofalo, Diana C; Reimbaeva, Maya; Scott, Amie M; Jiang, Lili; Cappell, Katherine; Lewandowski, David; Bonafede, Machaon; Brzozowski, Kaylen; Drebert, Zuzanna; Temple, Mike; Tawadrous, Margaret; Pixton, Glenn C; Alami, Niki; Kelly, Scott P; Aliabadi, Negar; Begier, Elizabeth; Swan, Joshua T
微生物学
发表日期：2024
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Ceftazidime-Avibactam in the Treatment of Patients with Bacteremia or Nosocomial Pneumonia: A Systematic Review and Meta-analysis

头孢他啶-阿维巴坦治疗菌血症或医院获得性肺炎患者的疗效：系统评价和荟萃分析

期刊:Infectious Diseases and Therapy
影响因子:5.3
doi:10.1007/s40121-024-00999-y
Shields, Ryan K; Horcajada, Juan P; Kamat, Shweta; Irani, Paurus M; Tawadrous, Margaret; Welte, Tobias
肺炎
发表日期：2024
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Correction to: Ceftazidime‑Avibactam in the Treatment of Patients with Bacteremia or Nosocomial Pneumonia: A Systematic Review and Meta‑analysis

更正：头孢他啶-阿维巴坦治疗菌血症或医院获得性肺炎患者：系统评价和荟萃分析

期刊:Infectious Diseases and Therapy
影响因子:5.3
doi:10.1007/s40121-024-01033-x
Shields, Ryan K; Horcajada, Juan P; Kamat, Shweta; Irani, Paurus M; Tawadrous, Margaret; Welte, Tobias
肺炎
发表日期：2024
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Pharmacokinetics, safety, and tolerability of fosmanogepix IV to oral switch and multiple IV doses in healthy participants

在健康受试者中，福斯马诺吉匹静脉注射转口服以及多次静脉注射的药代动力学、安全性和耐受性

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.01455-23
Hodges, Michael R; Hazel, Susan; Kramer, William G; van Hoogdalem, Ewoud-Jan; van Marle, Sjoerd; Tawadrous, Margaret; Jakate, Abhijeet
发表日期：2024
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A phase 1 open label study to assess the human mass balance and metabolite profile of (14)C-fosmanogepix, a novel Gwt-1 inhibitor in healthy male participants

一项 1 期开放标签研究，旨在评估新型 Gwt-1 抑制剂 (14)C-fosmanogepix 在健康男性受试者中的人体质量平衡和代谢物谱。

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.00273-24
Hodges, Michael R; Ople, Eric; Evans, Philip; Pantophlet, A J Andre; Richardson, Jessica; Williams, Dylan; Tripathy, Sakambari; Tawadrous, Margaret; Jakate, Abhijeet
代谢
发表日期：2024
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Phase 1 drug-drug interaction study to assess the effect of CYP3A4 inhibition and pan-CYP induction on the pharmacokinetics and safety of fosmanogepix in healthy participants

一项评估CYP3A4抑制和泛CYP诱导对健康受试者福斯马诺吉匹（fosmanogepix）药代动力学和安全性影响的I期药物相互作用研究

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.01650-23
Hodges, Michael R; van Marle, Sjoerd; Kramer, William G; Ople, Eric; Tawadrous, Margaret; Jakate, Abhijeet
CYP3A4
发表日期：2024
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Safety and Pharmacokinetics of Intravenous and Oral Fosmanogepix, a First-in-Class Antifungal Agent, in Healthy Volunteers

在健康志愿者中静脉注射和口服福斯马诺吉匹（一种首创抗真菌药物）的安全性和药代动力学

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.01623-22
Hodges, Michael R; Ople, Eric; Wedel, Pamela; Shaw, Karen J; Jakate, Abhijeet; Kramer, William G; Marle, Sjoerd van; van Hoogdalem, Ewoud-Jan; Tawadrous, Margaret
微生物学
发表日期：2023
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