日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Cholesterol-dependent control of endosomal escape regulates intracellular trafficking of small interfering RNA therapeutics and interactions with small molecule drugs

胆固醇依赖性内体逃逸调控小干扰RNA疗法的细胞内运输及其与小分子药物的相互作用

期刊:Journal of Pharmacology and Experimental Therapeutics
影响因子:3.8
doi:10.1016/j.jpet.2025.103802
Tawfik, Sherouk M; Giang Nguyen, Le Tra; Jin, Jing; Armanios, Beshoy; Zhong, Xiao-Bo
信号转导
细胞生物学
代谢
发表日期：2026
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Impact on efficacy of target reduction of two FDA-approved ASO drugs by intracellular glucose levels in in vitro cell models.

细胞内葡萄糖水平对两种 FDA 批准的 ASO 药物靶点降低的疗效在体外细胞模型中的影响

期刊:Molecular Therapy-Nucleic Acids
影响因子:6.1
doi:10.1016/j.omtn.2025.102487
Nguyen Le Tra Giang, Tawfik Sherouk M, Jin Jing, Durwin Andrea, Zhong Xiao-Bo
细胞生物学
发表日期：2025
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Intracellular fatty acid levels differentially impact target silencing by FDA-approved siRNA drugs.

细胞内脂肪酸水平对FDA批准的siRNA药物靶向沉默的影响存在差异

期刊:Biochemical Pharmacology
影响因子:5.6
doi:10.1016/j.bcp.2025.117192
Tawfik Sherouk M, Giang Nguyen Le Tra, Jin Jing, Zhong Xiao-Bo
细胞生物学
发表日期：2025
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Visualization of CYP3A4 expression at both mRNA and protein levels simultaneously at single cell resolution in various conditions using RNAscope combined with immunofluorescence.

利用 RNAscope 结合免疫荧光技术，在各种条件下以单细胞分辨率同时可视化 CYP3A4 在 mRNA 和蛋白质水平上的表达。

期刊:Drug Metabolism and Disposition
影响因子:4
doi:10.1016/j.dmd.2025.100123
Jin Jing, Tawfik Sherouk M, Nguyen Le Tra Giang, Armanios Beshoy, Zhong Xiao-Bo
细胞生物学
ASC
CYP3A4
单细胞
发表日期：2025
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Indication-Specific Dosing and Dose-Evaluation Strategies in New Indications for Non-Oncology Monoclonal Antibodies

非肿瘤单克隆抗体新适应症的适应症特异性给药和剂量评估策略

期刊:Journal of Clinical Pharmacology
影响因子:2.3
doi:10.1002/jcph.70000
Tawfik, Sherouk M; Tang, Fei
单克隆抗体
肿瘤
肿瘤免疫
发表日期：2025
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Targeting the Liver with Nucleic Acid Therapeutics for the Treatment of Systemic Diseases of Liver Origin

利用核酸疗法靶向肝脏治疗肝源性系统性疾病

期刊:Pharmacological Reviews
影响因子:17.3
doi:10.1124/pharmrev.123.000815
Gogate, Anagha; Belcourt, Jordyn; Shah, Milan; Wang, Alicia Zongxun; Frankel, Alexis; Kolmel, Holly; Chalon, Matthew; Stephen, Prajith; Kolli, Aarush; Tawfik, Sherouk M; Jin, Jing; Bahal, Raman; Rasmussen, Theodore P; Manautou, José E; Zhong, Xiao-Bo
发表日期：2023
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Climate change, human health, and the exposome: Utilizing OMIC technologies to navigate an era of uncertainty

气候变化、人类健康与暴露组：利用组学技术应对不确定时代

期刊:Frontiers in Public Health
影响因子:3.4
doi:10.3389/fpubh.2022.973000
Abdelzaher, Hana; Tawfik, Sherouk M; Nour, Ahmed; Abdelkader, Sarah; Elbalkiny, Shaimaa Tarek; Abdelkader, Mohamed; Abbas, Walaa A; Abdelnaser, Anwar
发表日期：2022
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