日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Trimodulin supports antibacterial defence and restricts inflammation in preclinical pneumonia models

三调蛋白在临床前肺炎模型中支持抗菌防御并抑制炎症

Nouailles, Geraldine; Bischoff, Romina; Linke, Kerstin; Taylor, Alexander; Gutbier, Birgitt; Pennitz, Peter; Goekeri, Cengiz; Kunder, Sandra; Voß, Anne; Brömel, Theresa C; Kershaw, Olivia; Milek, Miha; Farztdinov, Vadim; Mülleder, Michael; Weissmüller, Sabrina; Heinz, Corina C; Visser, Mayken; Bohlaender, Fabian; Ahrens, Katharina; Beule, Dieter; Gruber, Achim D; Koenig, Martin; Witzenrath, Martin

Amyloid fibril polymorphism: Structural mechanisms of assembly and the links to disease

淀粉样蛋白原纤维多态性:组装的结构机制及其与疾病的联系

Taylor, Alexander I P; Radford, Sheena E

Crystal Structure of Měnglà Virus Nucleoprotein Bound by a Poorly Cross-Reactive Anti-Marburg Virus Nanobody Highlights a Single Amino Acid Affinity Switch, a Feature Also Evident in Dehong Virus

弱交叉反应性抗马尔堡病毒纳米抗体与门格拉病毒核蛋白结合的晶体结构揭示了单个氨基酸亲和力转换,这一特征在德宏病毒中也有体现。

Sherwood, Laura Jo; Taylor, Alexander Bryan; Olsen, Shaun K; Hayhurst, Andrew

Case Report: Partial neurectomy and limb-sparing treatment for SOX-10 expressing epithelioid malignant nerve sheath tumour of the tibial nerve

病例报告:胫神经SOX-10表达上皮样恶性神经鞘瘤的部分神经切除和保肢治疗

Spencer-Taylor, Alexander; Yaffy, Dylan; Marti, Juan; Miguel-Garcés, Maria; Raimondi, Francesca

Recurrent vulvar ulcers led to the multidisciplinary management of a rare vulvar condition, Langerhans cell histiocytosis

反复发作的外阴溃疡最终导致了对一种罕见外阴疾病——朗格汉斯细胞组织细胞增生症的多学科治疗。

Kalwani, Shubham; Fishbach, Shira; Taylor, Alexander S; Parker-Featherstone, Ebony C; Ahmed, Asra; Saunders, Natalie A; Welch, Kathryn C

High-throughput discovery of fluoroprobes that recognize amyloid fibril polymorphs.

利用高通量方法发现可识别淀粉样蛋白原纤维多晶型的荧光探针。

Carroll Emma C, Yang Hyunjun, Powell Wyatt C, Charvat Annemarie F, Oehler Abby, Jones Julia G, Montgomery Kelly M, Yung Anthony, Millbern Zoe, Taylor Alexander I P, Wilkinson Martin, Ranson Neil A, Radford Sheena E, Vinueza Nelson R, DeGrado William F, Mordes Daniel A, Condello Carlo, Gestwicki Jason E

Mapping the Role of Monomer Conformation in the Amyloid Formation of α-Synuclein Splice Variants

α-突触核蛋白剪接变体的淀粉样蛋白形成中单体构象的作用机制

Dewison, Katherine M; Taylor, Alexander I P; Brockwell, David J; Radford, Sheena E

Kinetic Steering of Amyloid Formation and Polymorphism by Canagliflozin, a Type-2 Diabetes Drug

卡格列净(一种2型糖尿病药物)对淀粉样蛋白形成和多态性的动力学调控

Taylor, Alexander I P; Xu, Yong; Wilkinson, Martin; Chakraborty, Pijush; Brinkworth, Alice; Willis, Leon F; Zhuravleva, Anastasia; Ranson, Neil A; Foster, Richard; Radford, Sheena E

Azapeptide-Based SARS-CoV-2 Main Protease Inhibitors: Design, Synthesis, Enzyme Inhibition, Structural Determination, and Antiviral Activity

基于氮杂肽的SARS-CoV-2主蛋白酶抑制剂:设计、合成、酶抑制、结构鉴定和抗病毒活性

Flury, Philipp; Vishwakarma, Jyoti; Sylvester, Katharina; Higashi-Kuwata, Nobuyo; Dabrowska, Agnieszka K; Delgado, Renee; Cuell, Ashley; Basu, Rahul; Taylor, Alexander B; de Oliveira, Ellen Gonçalves; Magalhães Serafim, Mateus Sá; Qiao, Jingxin; Chen, Yan; Yang, Shengyong; O'Donoghue, Anthony J; Mitsuya, Hiroaki; Gütschow, Michael; Laufer, Stefan A; Müller, Christa E; Harris, Reuben S; Pillaiyar, Thanigaimalai

Development of a Novel Compound Effective Against Juvenile, Adult, and Drug-Resistant Schistosoma Species

开发一种对幼年、成年和耐药血吸虫均有效的新型化合物

Alwan, Sevan N; Taylor, Alexander B; McHardy, Stanton F; Cameron, Michael D; LoVerde, Philip T