日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Selective neuronal restoration of progranulin does not prevent the frontotemporal dementia like-phenotype of progranulin knockout mice

选择性地恢复神经元中前粒蛋白的表达并不能阻止前粒蛋白敲除小鼠出现额颞叶痴呆样表型。

Weyer, Marc-Philipp; Hahnefeld, Lisa; Franck, Luisa; Angioni, Carlo; Klein, Matthias; Geisslinger, Gerd; Schäfer, Michael K E; Tegeder, Irmgard

Modest improvement of metabolic and behavioral deficits with long-term ambroxol treatment in a Pink1(-/-)SNCA(A53T) double mutant mouse model of Parkinson's disease

在帕金森病Pink1(-/-)SNCA(A53T)双突变小鼠模型中,长期氨溴索治疗可轻微改善代谢和行为缺陷。

Franck, Luisa; Valek, Lucie; Hahnefeld, Lisa; Trautmann, Sandra; Angioni, Carlo; Weyer, Marc-Philipp; Thomas, Dominique; Gurke, Robert; Wittig, Ilka; Geisslinger, Gerd; Tegeder, Irmgard

CSF1R and IL1R1 inhibitors synergistically attenuate the early pathogenesis of traumatic brain injury in mice

CSF1R 和 IL1R1 抑制剂协同减轻小鼠创伤性脑损伤的早期发病机制

Wang, Sudena; Wang, Yong; Strehle, Jenny; Wernersbach, Isa; Papakonstantinou, Ermis; Somnuke, Pawit; Ritter, Katharina; Klein, Matthias; Tegeder, Irmgard; Schäfer, Michael K E

The endocannabinoid anandamide mediates anti-inflammatory effects through activation of NR4A nuclear receptors.

内源性大麻素花生四烯酸乙醇胺通过激活 NR4A 核受体发挥抗炎作用

Teichmann Tom, Pflüger-Müller Beatrice, Giménez Virna Margarita Martín, Sailer Fiona, Dirks Henrik, Zehr Simonida, Warwick Timothy, Brettner Felix, Munoz-Tello Paola, Zimmer Andreas, Tegeder Irmgard, Thomas Dominique, Gurke Robert, Günther Stefan, Heering Jan, Proschak Ewgenij, Geisslinger Gerd, Bibli Iris-S, Heringdorf Dagmar Meyer Zu, Manucha Walter, Windbergs Maike, Knapp Stefan, Weigert Andreas, Leisegang Matthias S, Kojetin Douglas, Brandes Ralf P

Plasma lipidomic and metabolomic profiles in high-grade glioma patients before and after 72-h presurgery water-only fasting

高级别胶质瘤患者术前72小时仅饮水禁食前后血浆脂质组学和代谢组学特征分析

Divé, Iris; Hahnefeld, Lisa; Wenger, Katharina J; Kögel, Donat; Steinbach, Joachim; Geisslinger, Gerd; Ronellenfitsch, Michael W; Tegeder, Irmgard

Valproic Acid Treatment after Traumatic Brain Injury in Mice Alleviates Neuronal Death and Inflammation in Association with Increased Plasma Lysophosphatidylcholines

丙戊酸治疗小鼠创伤性脑损伤后可减轻神经元死亡和炎症,并伴有血浆溶血磷脂酰胆碱水平升高。

Hummel, Regina; Dorochow, Erika; Zander, Sonja; Ritter, Katharina; Hahnefeld, Lisa; Gurke, Robert; Tegeder, Irmgard; Schäfer, Michael K E

Brain region specific regulation of anandamide (down) and sphingosine-1-phosphate (up) in association with anxiety (AEA) and resilience (S1P) in a mouse model of chronic unpredictable mild stress

在慢性不可预测轻度应激小鼠模型中,大脑区域特异性调节花生四烯酸乙醇胺(下调)和鞘氨醇-1-磷酸(上调)与焦虑(AEA)和韧性(S1P)相关。

Fischer, Caroline; Thomas, Dominique; Gurke, Robert; Tegeder, Irmgard

Correction: EGFL7 loss correlates with increased VEGF-D expression, upregulating hippocampal adult neurogenesis and improving spatial learning and memory

更正:EGFL7 缺失与 VEGF-D 表达增加相关,上调海马成年神经发生,并改善空间学习和记忆。

Barth, Kathrin; Vasić, Verica; McDonald, Brennan; Heinig, Nora; Wagner, Marc Christoph; Schumann, Ulrike; Röhlecke, Cora; Bicker, Frank; Schumann, Lana; Radyushkin, Konstantin; Baumgart, Jan; Tenzer, Stefan; Zipp, Frauke; Meinhardt, Matthias; Alitalo, Kari; Tegeder, Irmgard; Schmidt, Mirko H H

EGFL7 loss correlates with increased VEGF-D expression, upregulating hippocampal adult neurogenesis and improving spatial learning and memory.

EGFL7 的缺失与 VEGF-D 表达的增加相关,上调海马成年神经发生,改善空间学习和记忆

Barth Kathrin, Vasić Verica, McDonald Brennan, Heinig Nora, Wagner Marc-Christoph, Schumann Ulrike, Röhlecke Cora, Bicker Frank, Schumann Lana, Radyushkin Konstantin, Baumgart Jan, Tenzer Stefan, Zipp Frauke, Meinhardt Matthias, Alitalo Kari, Tegeder Irmgard, Schmidt Mirko H H

Tonic activation of GABA(B) receptors via GAT-3 mediated GABA release reduces network activity in the developing somatosensory cortex in GAD67-GFP mice

在GAD67-GFP小鼠中,通过GAT-3介导的GABA释放对GABA(B)受体的持续激活会降低发育中体感皮层的网络活动。

Ueberbach, Timo; Simacek, Clara A; Tegeder, Irmgard; Kirischuk, Sergei; Mittmann, Thomas