日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Lamin A/C loss promotes R-loop-mediated genomic instability and poor survival in small-cell lung cancer

层粘蛋白A/C的缺失会促进R环介导的基因组不稳定，并导致小细胞肺癌患者生存率降低。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2503387122
Schultz, Christopher W; Saha, Sourav; Dhall, Anjali; Zhang, Yang; Desai, Parth; Pongor, Lorinc S; Scheiblin, David A; Magidson, Valentin; Shuklah, Ravi P; Sebastian, Robin; Vekariya, Umeshkumar M; Ahmed, Shahbaz; Sun, Yilun; Redon, Christophe; Kumar, Suresh; Krishnamurthy, Manan; Dias, Henrique B; Aksenova, Vasilisa; Giordano, Elizabeth; Takahashi, Nobuyuki; Nirula, Michael; Arora, Mohit; Tabe, Chiori; Thomas, Maria Sebastian; Kumar, Rajesh; Arakawa, Yasuhiro; Jo, Ukhyun; Skorski, Tomasz; Teicher, Beverly A; Shreshta, Roshan; Aladjem, Mirit I; Lockett, Stephen; Dasso, Mary; Pommier, Yves; Sharma, Ajit K; Thomas, Anish
肺癌
细胞生物学
肿瘤
肿瘤免疫
发表日期：2025
文献求助 收藏

Polymerase Ѳ inhibitors combinations with approved and investigational agents in patient-derived tumor multi-cell type (mct) spheroids.

聚合酶 Ѳ 抑制剂与已批准和正在研究的药物在患者来源的肿瘤多细胞类型 (mct) 球体中的组合

期刊:Experimental and Molecular Pathology
影响因子:3.7
doi:10.1016/j.yexmp.2025.104978
Teicher Beverly A, Dexheimer Thomas S, Chen Li, Silvers Thomas, Jones Eric M, Coussens Nathan P, Eder J Paul, Doroshow James H
细胞生物学
肿瘤
肿瘤免疫
发表日期：2025
文献求助 收藏

RAS Pathway Inhibitors Combined with Targeted Agents Are Active in Patient-Derived Spheroids with Oncogenic KRAS Variants from Multiple Cancer Types

RAS通路抑制剂与靶向药物联合使用对多种癌症类型中携带致癌KRAS变异的患者来源球体具有活性

期刊:Cancer Research Communications
影响因子:3.3
doi:10.1158/2767-9764.CRC-24-0582
Davoudi, Zahra; Dexheimer, Thomas S; Coussens, Nathan P; Silvers, Thomas; Fox, Raymond G; Kemp, Samantha B; Juneja, Poorva; Morris, Joel; Hollingshead, Melinda G; Takebe, Naoko; Doroshow, James H; Teicher, Beverly A
信号转导
RAS
肿瘤
肿瘤免疫
发表日期：2025
文献求助 收藏

High-throughput combination screening of Pidnarulex and other G-quadruplex ligands in multi-cell type tumor spheroids

在多细胞类型肿瘤球体中对 Pidnarulex 和其他 G-四链体配体进行高通量组合筛选

期刊:SLAS Discovery
影响因子:2.7
doi:10.1016/j.slasd.2025.100284
Dexheimer, Thomas S; Coussens, Nathan P; Silvers, Thomas; Juneja, Poorva; Jones, Eric; Gore, Steven D; Kunkel, Mark W; Doroshow, James H; Teicher, Beverly A
细胞生物学
肿瘤
肿瘤免疫
发表日期：2025
文献求助 收藏

Combinatorial screen of targeted agents with the PI3K inhibitors inavolisib, alpelisib, duvelisib, and copanlisib in multi-cell type tumor spheroids.

在多细胞类型肿瘤球体中，对靶向药物与 PI3K 抑制剂 inavolisib、alpelisib、duvelisib 和 copanlisib 进行组合筛选

期刊:SLAS Discovery
影响因子:2.7
doi:10.1016/j.slasd.2025.100222
Dexheimer Thomas S, Davoudi Zahra, Coussens Nathan P, Silvers Thomas, Morris Joel, Takebe Naoko, Said Rabih, Moscow Jeffrey A, Doroshow James H, Teicher Beverly A
细胞生物学
肿瘤
PI3K/Akt
肿瘤免疫
发表日期：2025
文献求助 收藏

RNA processing kinase inhibitors and epigenetic inhibitors in combination with oncology drugs or investigational agents in multi-cell type patient-derived tumor cell line spheroids

RNA加工激酶抑制剂和表观遗传抑制剂与肿瘤药物或研究性药物联合用于多细胞类型患者来源的肿瘤细胞系球体

期刊:Cancer Chemotherapy and Pharmacology
影响因子:2.3
doi:10.1007/s00280-025-04800-w
Teicher, Beverly A; Dexheimer, Thomas S; Silvers, Thomas; Coussens, Nathan P; Jones, Eric; Gore, Steven D; Kunkel, Mark; Doroshow, James H
肿瘤
表观遗传
肿瘤免疫
信号转导
细胞生物学
肿瘤细胞
发表日期：2025
文献求助 收藏

Targeted therapy combinations with ipatasertib in multi-cell type 3D tumor spheroid models

在多细胞类型 3D 肿瘤球体模型中，靶向治疗联合 ipatasertib 的疗效

期刊:
影响因子:
doi:10.20935/acadonco7726
Teicher, Beverly A; Takebe, Naoko; Dexheimer, Thomas S; Silvers, Thomas E; Coussens, Nathan P; Hollingshead, Melinda G; Doroshow, James H
3D/类器官
细胞生物学
肿瘤
肿瘤免疫
发表日期：2025
文献求助 收藏

Lamin A/C Deficiency Drives Genomic Instability and Poor Survival in Small-Cell Lung Cancer through Increased R-loop Accumulation.

层粘蛋白 A/C 缺乏通过增加 R 环积累驱动小细胞肺癌的基因组不稳定和生存率低。

期刊:
影响因子:
doi:10.1101/2025.04.29.651052
Schultz Christopher W, Saha Sourav, Dhall Anjali, Zhang Yang, Desai Parth, Pongor Lorinc S, Scheiblin David A, Magidson Valentin, Sun Yilun, Redon Christophe, Kumar Suresh, Krishnamurthy Manan, Dias Henrique B, Aksenova Vasilisa, Giordano Elizabeth, Takahashi Nobuyuki, Nirula Michael, Arora Mohit, Tabe Chiori, Thomas Maria, Kumar Rajesh, Arakawa Yasuhiro, Jo Ukhyun, Teicher Beverly A, Aladjem Mirit I, Lockett Stephen, Dasso Mary, Pommier Yves, Sharma Ajit K, Thomas Anish
肺癌
细胞生物学
发表日期：2025
文献求助 收藏

RNA processing kinase inhibitors and epigenetic inhibitors in combination with oncology drugs or investigational agents in multi-cell type patient-derived tumor cell line spheroids.

RNA 加工激酶抑制剂和表观遗传抑制剂与肿瘤药物或研究性药物联合用于多细胞类型患者来源的肿瘤细胞系球体

期刊:
影响因子:
doi:10.21203/rs.3.rs-6602839/v1
Teicher Beverly A, Dexheimer Thomas S, Silvers Thomas, Coussens Nathan P, Jones Eric, Gore Steven D, Kunkel Mark, Doroshow James H
细胞生物学
肿瘤
表观遗传
肿瘤免疫
发表日期：2025
文献求助 收藏

Lessons learned from 20 years of preclinical testing in pediatric cancers

从20年的儿科癌症临床前试验中汲取的经验教训

期刊:Pharmacology & Therapeutics
影响因子:12.5
doi:10.1016/j.pharmthera.2024.108742
Smith, Malcolm A; Houghton, Peter J; Lock, Richard B; Maris, John M; Gorlick, Richard; Kurmasheva, Raushan T; Li, Xiao-Nan; Teicher, Beverly A; Chuang, Jeffrey H; Dela Cruz, Filemon S; Dyer, Michael A; Kung, Andrew L; Lloyd, Michael W; Mossé, Yael P; Stearns, Timothy M; Stewart, Elizabeth A; Bult, Carol J; Erickson, Stephen W
肿瘤
肿瘤免疫
发表日期：2024
文献求助 收藏