日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A model-based prion vaccine protects a transgenic mouse line carrying a Gerstmann-Sträussler-Scheinker disease mutation

一种基于模型的朊病毒疫苗能够保护携带格斯特曼-施特劳斯勒-沙因克氏病突变的转基因小鼠品系

期刊:Acta Neuropathologica
影响因子:9.3
doi:10.1007/s00401-026-03015-4
Fang, Andrew; Tang, Xinli; Fleming, Madeleine; Tancowny, Brian; Wang, Xiongyao; Wang, YongLiang; Daude, Nathalie; Dorosh, Lyudmyla; Fleck, Shelaine C; Rathod, Vineet; Coustou, Virginie; Cervantes, Silvia A; Velásquez, Camilo Duque; Westaway, David; Aiken, Judd; McKenzie, Debbie; Telling, Glenn; Stepanova, Maria; Saupe, Sven J; Siemer, Ansgar B; Wille, Holger
微生物学
发表日期：2026
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Refined Transgenic Mouse Models Which Recapitulate the Natural Features of Chronic Wasting Disease With Rapid Prion Disease Onsets

能够重现慢性消耗性疾病自然特征并快速发生朊病毒疾病的改良转基因小鼠模型

期刊:Journal of Infectious Diseases
影响因子:4.5
doi:10.1093/infdis/jiaf529
DeFranco, Joseph P; Kim, Sehun; Atkinson, Zoe N; Crowell, Jenna; Lei, Samantha; Bian, Jifeng; Telling, Glenn C
微生物学
Mouse
发表日期：2026
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Enhanced lysosomal activity prevents infection with PrP(Sc) and the seeding activity of α-synuclein & tau prions

溶酶体活性增强可阻止 PrP(Sc) 感染以及 α-突触核蛋白和 tau 朊病毒的播散活性。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2025.111050
Mercer, Robert C C; Le, Nhat T T; Mirza-Romero, Nadia A; Orbe, Isabel C; Flaherty, Erin; DeFranco, Joseph P; Lavigna, Giada; Gatdula, Jean R P; Fraser, Douglas G; Sundaravadivelu, Aravind; Vultaggio, Janelle S; Beeler, Aaron B; Chiesa, Roberto; Telling, Glenn C; Harris, David A
炎症/感染
神经科学
微生物学
发表日期：2026
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Kerogen-rich rocks influence growth and composition of an anaerobic microbial community

富含干酪根的岩石会影响厌氧微生物群落的生长和组成。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-026-42062-5
Waajen, Annemiek C; de Wit, Wessel; Sánchez-Román, Mónica; Edgar, John O; Telling, Jon; Cockell, Charles S
微生物学
发表日期：2026
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Leveraging the dominant-negative effect of the kuru-protective G127V prion protein variant as a novel therapeutic strategy

利用库鲁病保护性朊病毒蛋白变体G127V的显性负效应作为一种新型治疗策略

期刊:
影响因子:
doi:10.64898/2026.02.17.703887
Gatdula, Jean R P; Orbe, Isabel C; Tolton, Samantha G; Saunders, Linnea M; Vultaggio, Janelle S; Mercer, Robert C C; Bartz, Jason C; Telling, Glenn C; Eraña, Hasier; Castilla, Joaquín; Harris, David A
微生物学
发表日期：2026
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Regulated coexpression of PrP from different species in mice impacts the replication and host range properties of prion strains

小鼠体内不同物种PrP的调控性共表达会影响朊病毒株的复制和宿主范围特性。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2515284122
DeFranco, Joseph P; Bian, Jifeng; Kim, Sehun; Atkinson, Zoe N; Crowell, Jenna; Kang, Hae-Eun; Bodrogi, Hannah O; Christiansen, Jeffrey R; Díaz-Domínguez, Carlos M; Telling, Glenn C
微生物学
信号转导
发表日期：2025
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Detection of Chronic Wasting Disease Prions in Raw, Processed, and Cooked Elk Meat, Texas, USA

美国德克萨斯州生麋鹿肉、加工麋鹿肉和熟麋鹿肉中慢性消耗性疾病朊病毒的检测

期刊:Emerging Infectious Diseases
影响因子:6.6
doi:10.3201/eid3102.240906
Benavente, Rebeca; Brydon, Fraser; Bravo-Risi, Francisca; Soto, Paulina; Reed, J Hunter; Lockwood, Mitch; Telling, Glenn; Barria, Marcelo A; Morales, Rodrigo
微生物学
发表日期：2025
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Detection of Prions in Wild Pigs (Sus scrofa) from Areas with Reported Chronic Wasting Disease Cases, United States

美国报告有慢性消耗性疾病病例地区的野猪（Sus scrofa）体内朊病毒的检测

期刊:Emerging Infectious Diseases
影响因子:6.6
doi:10.3201/eid3101.240401
Soto, Paulina; Bravo-Risi, Francisca; Benavente, Rebeca; Stimming, Tucker H; Bodenchuk, Michael J; Whitley, Patrick; Turnage, Clint; Spraker, Terry R; Greenlee, Justin; Telling, Glenn; Malmberg, Jennifer; Gidlewski, Thomas; Nichols, Tracy; Brown, Vienna R; Morales, Rodrigo
微生物学
发表日期：2025
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Conservation of strain properties of bank vole-adapted chronic wasting disease in the absence of glycosylation and membrane anchoring

在缺乏糖基化和膜锚定的情况下，田鼠适应性慢性消耗性疾病的菌株特性得以保留

期刊:Neurobiology of Disease
影响因子:5.6
doi:10.1016/j.nbd.2025.106894
Vidal, Enric; Eraña, Hasier; Charco, Jorge M; Lorenzo, Nuria L; Giler, Samanta; Ordóñez, Montserrat; Fernández-Muñoz, Eva; San-Juan-Ansoleaga, Maitena; Telling, Glenn C; Sánchez-Martín, Manuel A; Geijo, Mariví; Requena, Jesús R; Castilla, Joaquín
发表日期：2025
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Effect of primary structural variation on cervid prion protein in flexibility, stability, and spontaneous misfolding propensity

一级结构变异对鹿朊病毒蛋白的柔性、稳定性和自发错误折叠倾向的影响

期刊:Neurobiology of Disease
影响因子:5.6
doi:10.1016/j.nbd.2025.107005
Díaz-Domínguez, Carlos M; Eraña, Hasier; Peccati, Francesca; Vidal, Enric; Charco, Jorge M; Sampedro-Torres-Quevedo, Cristina; Pérez-Castro, Miguel A; Lorenzo, Nuria L; Giler, Samanta; Telling, Glenn C; Geijo, Mariví; Requena, Jesús R; Jiménez-Osés, Gonzalo; Castilla, Joaquín
微生物学
发表日期：2025
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