Linsitinib Decreases Thyrotropin-Induced Thyroid Hormone Synthesis by Inhibiting Crosstalk Between Thyroid-Stimulating Hormone and Insulin-Like Growth Factor 1 Receptors in Human Thyrocytes In Vitro and In Vivo in Mice.

Linsitinib 通过抑制人甲状腺细胞中促甲状腺激素和胰岛素样生长因子 1 受体之间的串扰，降低促甲状腺激素诱导的甲状腺激素合成（体外和体内小鼠）