日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

The crystal and cryo-EM structures of PLCγ2 reveal dynamic interdomain recognitions in autoinhibition

PLCγ2的晶体结构和冷冻电镜结构揭示了自身抑制中动态的结构域间识别

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.adn6037
Shin, Young-Cheul; Plummer-Medeiros, Ashlee Marie; Mungenast, Alison; Choi, Hyeong-Wook; TenDyke, Karen; Zhu, Xiaojie; Shepard, Jennifer; Sanders, Kristen; Zhuang, Ningning; Hu, Liang; Qian, Dongming; Song, Kangkang; Xu, Chen; Wang, John; Poda, Suresh B; Liao, Maofu; Chen, Yu
发表日期：2024
文献求助 收藏

Pharmacologic Activation of STING in the Bladder Induces Potent Antitumor Immunity in Non-Muscle Invasive Murine Bladder Cancer

膀胱中 STING 的药理激活可在非肌层侵袭性小鼠膀胱癌中诱导强效抗肿瘤免疫

期刊:Molecular Cancer Therapeutics
影响因子:5.3
doi:10.1158/1535-7163.MCT-21-0780
Kuan-Chun Huang, Dinesh Chanda, Shannon McGrath, Vaishali Dixit, Chi Zhang, Jiayi Wu, Karen Tendyke, Huilan Yao, Renee Hukkanen, Noel Taylor, David Verbel, Dae-Shik Kim, Atsushi Endo, Thomas A Noland, Yu Chen, Mark Matijevic, John Wang, Janna Hutz, Nadeem Sarwar, Francis G Fang, Xingfeng Bao
肿瘤
膀胱癌
发表日期：2022
文献求助 收藏

Neuropilin-1 drives tumor-specific uptake of chlorotoxin

神经纤毛蛋白-1 驱动肿瘤特异性吸收氯毒素

期刊:Cell Communication and Signaling
影响因子:8.2
doi:10.1186/s12964-019-0368-9
Sharon McGonigle, Utpal Majumder, Donna Kolber-Simonds, Jiayi Wu, Andrew Hart, Thomas Noland, Karen TenDyke, Daniel Custar, Danyang Li, Hong Du, Maarten H D Postema, W George Lai, Natalie C Twine, Mary Woodall-Jappe, Kenichi Nomoto
神经
肿瘤
发表日期：2019
文献求助 收藏

Leiodermatolide, a novel marine natural product, has potent cytotoxic and antimitotic activity against cancer cells, appears to affect microtubule dynamics, and exhibits antitumor activity

Leiodermatolide 是一种新型海洋天然产物，具有强大的细胞毒性和抗癌细胞有丝分裂活性，似乎能够影响微管动力学，并表现出抗肿瘤活性

期刊:International Journal of Cancer
影响因子:5.7
doi:10.1002/ijc.30253
Esther A Guzmán, Qunli Xu, Tara P Pitts, Kaoru Ogawa Mitsuhashi, Cheryl Baker, Patricia A Linley, Judy Oestreicher, Karen Tendyke, Priscilla L Winder, Edward M Suh, Amy E Wright
肿瘤
肿瘤细胞
发表日期：2016
文献求助 收藏

Apratoxin A Shows Novel Pancreas-Targeting Activity through the Binding of Sec 61

Apratoxin A 通过与 Sec 61 结合表现出新的胰腺靶向活性

期刊:Molecular Cancer Therapeutics
影响因子:5.3
doi:10.1158/1535-7163.MCT-15-0648
Kuan-Chun Huang, Zhihong Chen, Yimin Jiang, Sandeep Akare, Donna Kolber-Simonds, Krista Condon, Sergei Agoulnik, Karen Tendyke, Yongchun Shen, Kuo-Ming Wu, Steven Mathieu, Hyeong-Wook Choi, Xiaojie Zhu, Hajime Shimizu, Yoshihiko Kotake, William H Gerwick, Toshimitsu Uenaka, Mary Woodall-Jappe, Kenic
信号转导
发表日期：2016
文献求助 收藏

Design, Synthesis, and Evaluation of Irciniastatin Analogues: Simplification of the Tetrahydropyran Core and the C(11) Substituents

伊西尼他汀类似物的设计、合成和评价：四氢吡喃核心和C(11)取代基的简化

期刊:Journal of Organic Chemistry
影响因子:3.6
doi:10.1021/acs.joc.5b02771
Liu, Qi; An, Chihui; TenDyke, Karen; Cheng, Hongsheng; Shen, Young Yongchun; Hoye, Adam T; Smith, Amos B 3rd
发表日期：2016
文献求助 收藏

Small molecule schweinfurthins selectively inhibit cancer cell proliferation and mTOR/AKT signaling by interfering with trans-Golgi-network trafficking

小分子schweinfurthins通过干扰跨高尔基网络运输选择性地抑制癌细胞增殖和mTOR / AKT信号传导

期刊:Cancer Biology & Therapy
影响因子:4.4
doi:10.1080/15384047.2015.1019184
Xingfeng Bao, Wanjun Zheng, Naoko Hata Sugi, Kishan L Agarwala, Qunli Xu, Zichun Wang, Karen Tendyke, Winnie Lee, Lana Parent, Wei Li, Hongsheng Cheng, Yongchun Shen, Noel Taylor, Zoltan Dezso, Hong Du, Yoshihiko Kotake, Nanding Zhao, John Wang, Maarten Postema, Mary Woodall-Jappe, Yasutaka Takase, 
免疫
细胞生物学
肿瘤细胞
mTOR
发表日期：2015
文献求助 收藏

High-Throughput Assay Development for Cystine-Glutamate Antiporter (xc-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma Cells

胱氨酸-谷氨酸反向转运蛋白 (xc-) 的高通量检测开发突出表明，胶质瘤细胞中胱氨酸的吸收速度比谷氨酸的释放速度更快

期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0127785
Ajit G Thomas, Rita Sattler, Karen Tendyke, Kara A Loiacono, Hans Hansen, Vishal Sahni, Yutaka Hashizume, Camilo Rojas, Barbara S Slusher
神经
肿瘤
胶质瘤
肿瘤细胞
HTRF
发表日期：2015
文献求助 收藏

Antiproliferative and antiplasmodial compounds from selected Streptomyces species

从选定的链霉菌属中分离得到的抗增殖和抗疟原虫化合物

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2015.07.103
Harinantenaina Rakotondraibe, L; Rasolomampianina, Rado; Park, Hyun-Young; Li, Jie; Slebodnik, Carla; Brodie, Peggy J; Blasiak, Leah C; Hill, Russel; TenDyke, Karen; Shen, Yongchun; Cassera, Maria B; Rejo, Felicite; Kingston, David G I
发表日期：2015
文献求助 收藏

Nitrogen-containing dimeric nor-multiflorane triterpene from a Turraea sp

从 Turraea sp. 中分离得到的含氮二聚体降多花烷三萜

期刊:Organic Letters
影响因子:5
doi:10.1021/ol500775r
Rasamison, Vincent E; Rakotondraibe, L Harinantenaina; Slebodnick, Carla; Brodie, Peggy J; Ratsimbason, Michel; TenDyke, Karen; Shen, Yongchun; Randrianjanaka, Lucien M; Kingston, David G I
发表日期：2014
文献求助 收藏