Inhibiting translation elongation by reducing eIF5A activity induces feedback inhibition of initiation, limiting tumour cell proliferation.
通过降低 eIF5A 活性来抑制翻译延伸，可诱导起始的反馈抑制，从而限制肿瘤细胞增殖。
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-66531-z
Sfakianos Aristeidis P, Raven Rebecca M, Smith Tom, Sun Xiao-Ming, Mulroney Thomas E, Pizzinga Mariavittoria, Dezi Veronica, Tenor Angela Rubio, Stoneley Mark, Cole Cameron H, Al-Doori Karam, Nur Hashim Ahmed, Pennie Rachel L, Powley Ian, Officer-Jones Leah, Sawarkar Ritwick, Turner Martin, MacFarlane Marion, Sansom Owen J, Bushell Martin, Le Quesne John, Harvey Robert F, Willis Anne E
