日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Development and Application of a Pseudovirus-Based Assay for Modelling SARS-CoV-2 Spike Protein Mediated Drug Screening

基于假病毒的检测方法在模拟SARS-CoV-2刺突蛋白介导的药物筛选中的应用

Khasanov, Shokhrukh A; Esaulkova, Iana L; Volobueva, Alexandrina S; Slita, Alexander V; Kriger, Daria V; Tentler, Dmitri; Yarovaya, Olga I; Sokolova, Anastasia S; Gorshkov, Andrey N; Dolgova, Anna S; Lavrentieva, Irina N; Dedkov, Vladimir G; Salakhutdinov, Nariman F; Zarubaev, Vladimir V

Sensitivity to an inhibitor of translation elongation in solid and hematologic cancers.

对实体瘤和血液肿瘤中翻译延伸抑制剂的敏感性

Gomes Nathan, Frederick Barbara, Tentler John, Su Tin Tin

Inhibition of knee joint sensory afferents alters covariation across strides between quadriceps muscles during locomotion

抑制膝关节感觉传入神经会改变运动过程中股四头肌间步态周期的协同变化

Alessandro, Cristiano; Prashara, Adarsh; Tentler, David P; Tresch, Matthew C

Alpha-actnin-4 (ACTN4) selectively affects the DNA double-strand breaks repair in non-small lung carcinoma cells

α-肌动蛋白-4 (ACTN4) 选择性影响非小细胞肺癌细胞中的 DNA 双链断裂修复

Daria Kriger, Ksenia Novitskaya, Giomar Vasileva, Ekaterina Lomert, Nikolai D Aksenov, Nikolai A Barlev, Dmitri Tentler

Preclinical Development of the Class-I-Selective Histone Deacetylase Inhibitor OKI-179 for the Treatment of Solid Tumors

用于治疗实体瘤的I类选择性组蛋白去乙酰化酶抑制剂OKI-179的临床前开发

Diamond, Jennifer R; Pitts, Todd M; Ungermannova, Dana; Nasveschuk, Christopher G; Zhang, Gan; Phillips, Andrew J; Bagby, Stacey M; Pafford, Jessica; Yacob, Betelehem W; Newton, Timothy P; Tentler, John J; Gittleman, Brian; Hartman, Sarah J; DeMattei, John A; Winkler, James D; Wendt, Michael K; Schiemann, William P; Eckhardt, S Gail; Liu, Xuedong; Piscopio, Anthony D

WEE1 Inhibition in Combination With Targeted Agents and Standard Chemotherapy in Preclinical Models of Pancreatic Ductal Adenocarcinoma

在胰腺导管腺癌的临床前模型中,WEE1抑制剂联合靶向药物和标准化疗的疗效

Hartman, Sarah J; Bagby, Stacey M; Yacob, Betelehem W; Simmons, Dennis M; MacBeth, Morgan; Lieu, Christopher H; Davis, S Lindsey; Leal, Alexis D; Tentler, John J; Diamond, Jennifer R; Eckhardt, S Gail; Messersmith, Wells A; Pitts, Todd M

Preclinical and Dose-Finding Phase I Trial Results of Combined Treatment with a TORC1/2 Inhibitor (TAK-228) and Aurora A Kinase Inhibitor (Alisertib) in Solid Tumors

TORC1/2抑制剂(TAK-228)与Aurora A激酶抑制剂(Alisertib)联合治疗实体瘤的临床前和剂量探索I期试验结果

Davis, S Lindsey; Ionkina, Anastasia A; Bagby, Stacey M; Orth, James D; Gittleman, Brian; Marcus, Joshua M; Lam, Elaine T; Corr, Bradley R; O'Bryant, Cindy L; Glode, Ashley E; Tan, Aik-Choon; Kim, Jihye; Tentler, John J; Capasso, Anna; Lopez, Kyrie L; Gustafson, Daniel L; Messersmith, Wells A; Leong, Stephen; Eckhardt, S Gail; Pitts, Todd M; Diamond, Jennifer R

Coordination amongst quadriceps muscles suggests neural regulation of internal joint stresses, not simplification of task performance

股四头肌之间的协调性表明神经系统对关节内部应力进行调节,而不是简化任务执行。

Alessandro, Cristiano; Barroso, Filipe O; Prashara, Adarsh; Tentler, David P; Yeh, Hsin-Yun; Tresch, Matthew C

RX-5902, a novel β-catenin modulator, potentiates the efficacy of immune checkpoint inhibitors in preclinical models of triple-negative breast Cancer

RX-5902 是一种新型 β-catenin 调节剂,可增强免疫检查点抑制剂在三阴性乳腺癌临床前模型中的疗效。

Tentler, John J; Lang, Julie; Capasso, Anna; Kim, Deog Joong; Benaim, Ely; Lee, Young B; Eisen, Andrew; Bagby, Stacey M; Hartman, Sarah J; Yacob, Betelehem W; Gittleman, Brian; Pitts, Todd M; Pelanda, Roberta; Eckhardt, S Gail; Diamond, Jennifer R

First-in-Class Phosphorylated-p68 Inhibitor RX-5902 Inhibits β-Catenin Signaling and Demonstrates Antitumor Activity in Triple-Negative Breast Cancer

首创的磷酸化p68抑制剂RX-5902抑制β-catenin信号通路,并在三阴性乳腺癌中展现抗肿瘤活性

Capasso, Anna; Bagby, Stacey M; Dailey, Kyrie L; Currimjee, Naomi; Yacob, Betelehem W; Ionkina, Anastasia; Frank, Julie G; Kim, Deog Joong; George, Christina; Lee, Young B; Benaim, Ely; Gittleman, Brian; Hartman, Sarah J; Tan, Aik Choon; Kim, Jihye; Pitts, Todd M; Eckhardt, S Gail; Tentler, John J; Diamond, Jennifer R