日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Antibody Structure and Function: The Basis for Engineering Therapeutics

抗体结构与功能:治疗工程的基础

Chiu, Mark L; Goulet, Dennis R; Teplyakov, Alexey; Gilliland, Gary L

A coiled conformation of amyloid-β recognized by antibody C706

抗体 C706 识别的淀粉样蛋白 β 的卷曲构象

Teplyakov, Alexey; Obmolova, Galina; Gilliland, Gary L

Crystal structure of CD27 in complex with a neutralizing noncompeting antibody

CD27 与中和性非竞争性抗体的复合物晶体结构

Teplyakov, Alexey; Obmolova, Galina; Malia, Thomas J; Gilliland, Gary L

Structural diversity in a human antibody germline library.

人类抗体种系库的结构多样性

Teplyakov Alexey, Obmolova Galina, Malia Thomas J, Luo Jinquan, Muzammil Salman, Sweet Raymond, Almagro Juan Carlos, Gilliland Gary L

Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8

抗tau抗体AT8识别磷酸化tau蛋白的表位定位和结构基础

Malia, Thomas J; Teplyakov, Alexey; Ernst, Robin; Wu, Sheng-Jiun; Lacy, Eilyn R; Liu, Xuesong; Vandermeeren, Marc; Mercken, Marc; Luo, Jinquan; Sweet, Raymond W; Gilliland, Gary L

Induced conformational change in human IL-4 upon binding of a signal-neutralizing DARPin.

信号中和 DARPin 与人 IL-4 结合后诱导构象变化

Obmolova Galina, Teplyakov Alexey, Malia Thomas J, Keough Edward, Luo Jinquan, Sweet Raymond, Jacobs Steven A, Yi Fang, Hippensteel Randi, O'Neil Karyn T, Gilliland Gary L

Canonical structures of short CDR-L3 in antibodies

抗体中短CDR-L3的典型结构

Teplyakov, Alexey; Gilliland, Gary L

Protein crystallization with microseed matrix screening: application to human germline antibody Fabs

利用微晶基质筛选进行蛋白质结晶:应用于人类生殖系抗体Fab片段

Obmolova, Galina; Malia, Thomas J; Teplyakov, Alexey; Sweet, Raymond W; Gilliland, Gary L

Antigen recognition by antibody C836 through adjustment of V(L)/V(H) packing

抗体 C836 通过调节 V(L)/V(H) 堆积方式识别抗原

Teplyakov, Alexey; Obmolova, Galina; Malia, Thomas; Gilliland, Gary

Crystallization of a challenging antigen-antibody complex: TLR3 ECD with three noncompeting Fabs

具有挑战性的抗原-抗体复合物的结晶:TLR3 ECD 与三个非竞争性 Fab 片段

Malia, Thomas J; Obmolova, Galina; Luo, Jinquan; Teplyakov, Alexey; Sweet, Raymond; Gilliland, Gary L