日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Comparison of rituximab induction and maintenance regimens in anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis: PK/PD modelling of ANCA and gammaglobulin levels in real-world patients

利妥昔单抗诱导和维持治疗方案在抗中性粒细胞胞浆抗体（ANCA）相关性血管炎中的比较：真实世界患者ANCA和丙种球蛋白水平的药代动力学/药效学模型

期刊:EBioMedicine
影响因子:10.8
doi:10.1016/j.ebiom.2025.105989
Pasquiers, Blaise; Blanchet, Benoit; Puéchal, Xavier; Declèves, Xavier; Cohen, Pascal; Goulvestre, Claire; Casadevall, Marion; Benhabiles, Inès; Vidal, Michel; Ternant, David; Terrier, Benjamin; Puszkiel, Alicja
细胞生物学
中性粒细胞
粒细胞
发表日期：2025
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Immunoglobulin G Receptors (FcγR), in Addition to Target-Antigen and Neonatal Fc Receptor (FcRn), Influence Rituximab Pharmacokinetics

除了靶抗原和新生儿Fc受体（FcRn）外，免疫球蛋白G受体（FcγR）也影响利妥昔单抗的药代动力学。

期刊:Clinical Pharmacokinetics
影响因子:4
doi:10.1007/s40262-025-01549-6
Ternant, David; Le Tilly, Olivier; Cartron, Guillaume; Desvignes, Céline; Bensalem, Amina; Mulleman, Denis; Bejan-Angoulvant, Theodora; Gouilleux-Gruart, Valérie; Paintaud, Gilles
信号转导
FcRn
免疫/内分泌
发表日期：2025
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Quality Assessment of Therapeutic Drug Monitoring Assays of Therapeutic Antibodies Across Europe: An Update

欧洲治疗性抗体治疗药物监测检测质量评估：最新进展

期刊:Basic & Clinical Pharmacology & Toxicology
影响因子:3.3
doi:10.1111/bcpt.70129
Bluett, James; Rumano, Merita; Martínez Becerra, María José; Loeff, Floris; Itik, Mehmet; Ternant, David; Desvignes, Céline; Mulleman, Denis; Skrede, Silje
发表日期：2025
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Prospective study to characterize adalimumab exposure in pediatric patients with rheumatic diseases

前瞻性研究旨在描述阿达木单抗在风湿病患儿中的暴露情况

期刊:Pediatric Rheumatology
影响因子:2.3
doi:10.1186/s12969-023-00930-8
Welzel, Tatjana; Golhen, Klervi; Atkinson, Andrew; Gotta, Verena; Ternant, David; Kuemmerle-Deschner, Jasmin B; Michler, Christine; Koch, Gilbert; van den Anker, Johannes N; Pfister, Marc; Woerner, Andreas
发表日期：2024
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Prediction of the Clinical Course of Immune Thrombocytopenia in Children by Platelet Kinetics

利用血小板动力学预测儿童免疫性血小板减少症的临床病程

期刊:Hemasphere
影响因子:14.6
doi:10.1097/HS9.0000000000000960
Lejeune, Julien; Raoult, Violette; Dubrasquet, Mathilde; Chauvin, Romane; Mallebranche, Coralie; Pellier, Isabelle; Monceaux, Françoise; Bayart, Sophie; Grain, Audrey; Gyan, Emmanuel; Ravalet, Noémie; Herault, Olivier; Ternant, David
血小板
免疫/内分泌
发表日期：2023
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Response to Biologic Drugs in Patients With Rheumatoid Arthritis and Antidrug Antibodies

类风湿性关节炎合并抗药抗体患者对生物制剂的反应

期刊:Jama Network Open
影响因子:9.7
doi:10.1001/jamanetworkopen.2023.23098
Bitoun, Samuel; Hässler, Signe; Ternant, David; Szely, Natacha; Gleizes, Aude; Richez, Christophe; Soubrier, Martin; Avouac, Jérome; Brocq, Olivier; Sellam, Jérémie; de Vries, Niek; Huizinga, Tom W J; Jury, Elizabeth C; Manson, Jessica J; Mauri, Claudia; Matucci, Andrea; Hacein Bey Abina, Salima; Mulleman, Denis; Pallardy, Marc; Broët, Philippe; Mariette, Xavier
关节炎
发表日期：2023
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Translation of Monoclonal Antibodies Pharmacokinetics from Animal to Human Using Physiologically Based Modeling in Open Systems Pharmacology (OSP) Suite: A Retrospective Analysis of Bevacizumab

使用开放系统药理学 (OSP) 套件中的生理学模型将单克隆抗体药代动力学从动物转化为人类：贝伐单抗的回顾性分析

期刊:Pharmaceutics
影响因子:4.9
doi:10.3390/pharmaceutics15082129
Blaise Pasquiers, Salih Benamara, Mathieu Felices, David Ternant, Xavier Declèves, Alicja Puszkiel
Human
单克隆抗体
发表日期：2023
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Curcumin and NCLX inhibitors share anti-tumoral mechanisms in microsatellite-instability-driven colorectal cancer

姜黄素和 NCLX 抑制剂在微卫星不稳定性驱动的结直肠癌中具有相同的抗肿瘤机制

期刊:Cellular and Molecular Life Sciences
影响因子:6.2
doi:10.1007/s00018-022-04311-4
Maxime Guéguinou, Sajida Ibrahim, Jérôme Bourgeais, Alison Robert, Trayambak Pathak, Xuexin Zhang, David Crottès, Jacques Dupuy, David Ternant, Valérie Monbet, Roseline Guibon, Hector Flores-Romero, Antoine Lefèvre, Stéphanie Lerondel, Alain Le Pape, Jean-François Dumas, Philippe G Frank, Alban Gira
肿瘤
肠癌
发表日期：2022
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Adjunction of a fish oil emulsion to cytarabine and daunorubicin induction chemotherapy in high-risk AML

在高危急性髓系白血病（AML）中，鱼油乳剂联合阿糖胞苷和柔红霉素诱导化疗

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-022-13626-y
Gyan, Emmanuel; Pigneux, Arnaud; Hunault, Mathilde; Peterlin, Pierre; Carré, Martin; Bay, Jacques-Olivier; Bonmati, Caroline; Gallego-Hernanz, Maria-Pilar; Lioure, Bruno; Bertrand, Philippe; Vallet, Nicolas; Ternant, David; Darrouzain, François; Picou, Frédéric; Béné, Marie-Christine; Récher, Christian; Hérault, Olivier
白血病
发表日期：2022
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Infliximab Efficacy May Be Linked to Full TNF-α Blockade in Peripheral Compartment-A Double Central-Peripheral Target-Mediated Drug Disposition (TMDD) Model

英夫利昔单抗的疗效可能与外周组织中TNF-α的完全阻断有关——双重中枢-外周靶点介导的药物处置（TMDD）模型

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics13111821
Ternant, David; Le Tilly, Olivier; Picon, Laurence; Moussata, Driffa; Passot, Christophe; Bejan-Angoulvant, Theodora; Desvignes, Céline; Mulleman, Denis; Goupille, Philippe; Paintaud, Gilles
TNF-α
发表日期：2021
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