日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Isogenic Sets of hiPSC-CMs Harboring Distinct KCNH2 Mutations Differ Functionally and in Susceptibility to Drug-Induced Arrhythmias

携带不同KCNH2突变的同源hiPSC-CMs在功能和对药物诱发心律失常的易感性方面存在差异

期刊:Stem Cell Reports
影响因子:5.1
doi:10.1016/j.stemcr.2020.10.005
Brandão, Karina O; van den Brink, Lettine; Miller, Duncan C; Grandela, Catarina; van Meer, Berend J; Mol, Mervyn P H; de Korte, Tessa; Tertoolen, Leon G J; Mummery, Christine L; Sala, Luca; Verkerk, Arie O; Davis, Richard P
KCNH2
发表日期：2020
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Blinded, Multicenter Evaluation of Drug-induced Changes in Contractility Using Human-induced Pluripotent Stem Cell-derived Cardiomyocytes

使用人类诱导性多能干细胞衍生的心肌细胞对药物引起的收缩力变化进行盲法、多中心评估

期刊:Toxicological Sciences
影响因子:3.4
doi:10.1093/toxsci/kfaa058
Umber Saleem, Berend J van Meer, Puspita A Katili, Nurul A N Mohd Yusof, Ingra Mannhardt, Ana Krotenberg Garcia, Leon Tertoolen, Tessa de Korte, Maria L H Vlaming, Karen McGlynn, Jessica Nebel, Anthony Bahinski, Kate Harris, Eric Rossman, Xiaoping Xu, Francis L Burton, Godfrey L Smith, Peter Clement
发育与干细胞
干细胞
Human
发表日期：2020
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Uncoupling DNA damage from chromatin damage to detoxify doxorubicin

将 DNA 损伤与染色质损伤分离，以解除阿霉素的毒性

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:
doi:10.1073/pnas.1922072117
Xiaohang Qiao, Sabina Y van der Zanden, Dennis P A Wander, Daniel M Borràs, Ji-Ying Song, Xiaoyang Li, Suzanne van Duikeren, Noortje van Gils, Arjo Rutten, Tessa van Herwaarden, Olaf van Tellingen, Elisa Giacomelli, Milena Bellin, Valeria Orlova, Leon G J Tertoolen, Sophie Gerhardt, Jimmy J Akkerman
信号转导
FCM
IF
IHC-P
WB
发表日期：2020
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Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes

同时测量兴奋-收缩耦合参数可识别 hiPSC 衍生心肌细胞收缩反应的潜在机制

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-019-12354-8
Berend J van Meer, Ana Krotenberg, Luca Sala, Richard P Davis, Thomas Eschenhagen, Chris Denning, Leon G J Tertoolen, Christine L Mummery
免疫
细胞生物学
其它细胞
发表日期：2019
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MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo

MUSCLEMOTION：一款多功能开源软件工具，用于量化体外和体内心肌细胞及心肌收缩

期刊:Circulation Research
影响因子:16.2
doi:10.1161/CIRCRESAHA.117.312067
Sala, Luca; van Meer, Berend J; Tertoolen, Leon G J; Bakkers, Jeroen; Bellin, Milena; Davis, Richard P; Denning, Chris; Dieben, Michel A E; Eschenhagen, Thomas; Giacomelli, Elisa; Grandela, Catarina; Hansen, Arne; Holman, Eduard R; Jongbloed, Monique R M; Kamel, Sarah M; Koopman, Charlotte D; Lachaud, Quentin; Mannhardt, Ingra; Mol, Mervyn P H; Mosqueira, Diogo; Orlova, Valeria V; Passier, Robert; Ribeiro, Marcelo C; Saleem, Umber; Smith, Godfrey L; Burton, Francis L; Mummery, Christine L
细胞生物学
发表日期：2018
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Correction for Muncan et al., "Rapid Loss of Intestinal Crypts upon Conditional Deletion of the Wnt/Tcf-4 Target Gene c-Myc"

对 Muncan 等人的论文“条件性删除 Wnt/Tcf-4 靶基因 c-Myc 导致肠隐窝快速丢失”的更正

期刊:Molecular and Cellular Biology
影响因子:2.7
doi:10.1128/MCB.00482-18
Muncan, Vanesa; Sansom, Owen J; Tertoolen, Leon; Phesse, Toby J; Begthel, Harry; Sancho, Elena; Cole, Alicia M; Gregorieff, Alex; Moreno de Alboran, Ignacio; Clevers, Hans; Clarke, Alan R
Wnt/β-Catenin
发表日期：2018
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Interpretation of field potentials measured on a multi electrode array in pharmacological toxicity screening on primary and human pluripotent stem cell-derived cardiomyocytes

在对原代和人类多能干细胞衍生的心肌细胞进行药物毒性筛选时，对多电极阵列上测量的场电位的解释

期刊:Biochemical and Biophysical Research Communications
影响因子:2.5
doi:10.1016/j.bbrc.2017.01.151
L G J Tertoolen, S R Braam, B J van Meer, R Passier, C L Mummery
发育与干细胞
干细胞
Human
发表日期：2018
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Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells

由人类多能干细胞共分化的心肌细胞和内皮细胞组成的三维心脏微组织

期刊:Development
影响因子:3.7
doi:10.1242/dev.143438
Elisa Giacomelli, Milena Bellin, Luca Sala, Berend J van Meer, Leon G J Tertoolen, Valeria V Orlova, Christine L Mummery
发育与干细胞
干细胞
Human
发表日期：2017
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Small molecule absorption by PDMS in the context of drug response bioassays

药物反应生物测定中 PDMS 对小分子的吸收

期刊:Biochemical and Biophysical Research Communications
影响因子:2.5
doi:10.1016/j.bbrc.2016.11.062
B J van Meer, H de Vries, K S A Firth, J van Weerd, L G J Tertoolen, H B J Karperien, P Jonkheijm, C Denning, A P IJzerman, C L Mummery0
多发性硬化症
发表日期：2017
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Serum supplemented culture medium masks hypertrophic phenotypes in human pluripotent stem cell derived cardiomyocytes

血清补充培养基掩盖人类多能干细胞衍生的心肌细胞的肥大表型

期刊:Journal of Cellular and Molecular Medicine
影响因子:4.3
doi:10.1111/jcmm.12356
Cheryl Dambrot, Stefan R Braam, Leon G J Tertoolen, Matthew Birket, Douwe E Atsma, Christine L Mummery
发育与干细胞
干细胞
Human
发表日期：2014
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