日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Models of β-amyloid induced Tau-pathology: the long and "folded" road to understand the mechanism

β-淀粉样蛋白诱导的Tau蛋白病理模型:理解其机制的漫长而曲折的道路

Stancu, Ilie-Cosmin; Vasconcelos, Bruno; Terwel, Dick; Dewachter, Ilse

Selective loss of noradrenaline exacerbates early cognitive dysfunction and synaptic deficits in APP/PS1 mice.

选择性地缺乏去甲肾上腺素会加剧 APP/PS1 小鼠的早期认知功能障碍和突触缺陷

Hammerschmidt Thea, Kummer Markus P, Terwel Dick, Martinez Ana, Gorji Ali, Pape Hans-Christian, Rommelfanger Karen S, Schroeder Jason P, Stoll Monika, Schultze Joachim, Weinshenker David, Heneka Michael T

Extracellular phosphorylation of the amyloid β-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease

淀粉样β肽的细胞外磷酸化促进阿尔茨海默病发病过程中毒性聚集体的形成。

Kumar, Sathish; Rezaei-Ghaleh, Nasrollah; Terwel, Dick; Thal, Dietmar R; Richard, Mélisande; Hoch, Michael; Mc Donald, Jessica M; Wüllner, Ullrich; Glebov, Konstantin; Heneka, Michael T; Walsh, Dominic M; Zweckstetter, Markus; Walter, Jochen

Neurodegeneration and neuroinflammation in cdk5/p25-inducible mice: a model for hippocampal sclerosis and neocortical degeneration

CDK5/P25诱导小鼠的神经退行性变和神经炎症:海马硬化和新皮质退行性变的模型

Muyllaert, David; Terwel, Dick; Kremer, Anna; Sennvik, Kristina; Borghgraef, Peter; Devijver, Herman; Dewachter, Ilse; Van Leuven, Fred

Amyloid activates GSK-3beta to aggravate neuronal tauopathy in bigenic mice

淀粉样蛋白激活GSK-3β,加剧双基因小鼠的神经元tau蛋白病变。

Terwel, Dick; Muyllaert, David; Dewachter, Ilse; Borghgraef, Peter; Croes, Sophie; Devijver, Herman; Van Leuven, Fred