日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The mycotoxin deoxynivalenol (DON) can deteriorate vaccination efficacy against porcine reproductive and respiratory syndrome virus (PRRSV) at subtoxic levels

脱氧雪腐镰刀菌烯醇 (DON) 是一种霉菌毒素,即使在亚毒性浓度下也能降低猪繁殖与呼吸综合征病毒 (PRRSV) 疫苗的效力。

Rückner, Antje; Plagge, Lisa; Heenemann, Kristin; Harzer, Maxi; Thaa, Bastian; Winkler, Janine; Dänicke, Sven; Kauffold, Johannes; Vahlenkamp, Thomas W

Alphavirus-induced hyperactivation of PI3K/AKT directs pro-viral metabolic changes

甲病毒诱导的 PI3K/AKT 过度活化可指导促病毒代谢变化

Michela Mazzon, Cecilia Castro, Bastian Thaa, Lifeng Liu, Margit Mutso, Xiang Liu, Suresh Mahalingam, Julian L Griffin, Mark Marsh, Gerald M McInerney

Mutation of CD2AP and SH3KBP1 Binding Motif in Alphavirus nsP3 Hypervariable Domain Results in Attenuated Virus

甲病毒nsP3高变域中CD2AP和SH3KBP1结合基序的突变导致病毒减毒

Margit Mutso, Ainhoa Moliner Morro, Cecilia Smedberg, Sergo Kasvandik, Muriel Aquilimeba, Mona Teppor, Liisi Tarve, Aleksei Lulla, Valeria Lulla, Sirle Saul, Bastian Thaa, Gerald M McInerney, Andres Merits, Margus Varjak

Elongated and Shortened Peptidomimetic Inhibitors of the Proprotein Convertase Furin

前蛋白转化酶弗林蛋白酶的延长和缩短的肽模拟物抑制剂

Kornelia Hardes, Teodora Ivanova, Bastian Thaa, Gerald M McInerney, Tove Irene Klokk, Kirsten Sandvig, Sebastian Künzel, Iris Lindberg, Torsten Steinmetzer

Combined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication

综合结构、生化和细胞证据表明,α病毒 nsP3 中的两种 FGDF 基序都是有效复制所必需的

Tim Schulte, Lifeng Liu, Marc D Panas, Bastian Thaa, Nicole Dickson, Benjamin Götte, Adnane Achour, Gerald M McInerney

The Antiviral Alkaloid Berberine Reduces Chikungunya Virus-Induced Mitogen-Activated Protein Kinase Signaling

抗病毒生物碱小檗碱可降低基孔肯雅病毒诱导的丝裂原活化蛋白激酶信号传导

Finny S Varghese, Bastian Thaa, Siti Naqiah Amrun, Diane Simarmata, Kai Rausalu, Tuula A Nyman, Andres Merits, Gerald M McInerney, Lisa F P Ng, Tero Ahola

Effects of an In-Frame Deletion of the 6k Gene Locus from the Genome of Ross River Virus

罗斯河病毒基因组中 6k 基因位点的框内删除的影响

Adam Taylor, Julian V Melton, Lara J Herrero, Bastian Thaa, Liis Karo-Astover, Peter W Gage, Michelle A Nelson, Kuo-Ching Sheng, Brett A Lidbury, Gary D Ewart, Gerald M McInerney, Andres Merits, Suresh Mahalingam

Correction for Thaa et al., Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization

对 Thaa 等人的研究更正:塞姆利基森林病毒和基孔肯雅病毒对磷脂酰肌醇-3-激酶-Akt-mTOR 通路的差异性激活依赖于 nsP3,并与复制复合物内化有关。

Thaa, Bastian; Biasiotto, Roberta; Eng, Kai; Neuvonen, Maarit; Götte, Benjamin; Rheinemann, Lara; Mutso, Margit; Utt, Age; Varghese, Finny; Balistreri, Giuseppe; Merits, Andres; Ahola, Tero; M McInerney, Gerald

Viral and cellular proteins containing FGDF motifs bind G3BP to block stress granule formation

含有 FGDF 基序的病毒和细胞蛋白与 G3BP 结合,阻止应激颗粒的形成

Marc D Panas, Tim Schulte, Bastian Thaa, Tatiana Sandalova, Nancy Kedersha, Adnane Achour, Gerald M McInerney

Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization

塞姆利基森林病毒和基孔肯雅病毒对磷脂酰肌醇-3-激酶-Akt-mTOR 的差异激活依赖于 nsP3 并与复制复合物内化有关

Bastian Thaa, Roberta Biasiotto, Kai Eng, Maarit Neuvonen, Benjamin Götte, Lara Rheinemann, Margit Mutso, Age Utt, Finny Varghese, Giuseppe Balistreri, Andres Merits, Tero Ahola, Gerald M McInerney