Lysibodies are IgG Fc fusions with lysin binding domains targeting Staphylococcus aureus wall carbohydrates for effective phagocytosis.
溶菌抗体是 IgG Fc 与溶菌素结合域的融合蛋白,靶向金黄色葡萄球菌细胞壁碳水化合物,以达到有效的吞噬作用
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1619249114
Raz Assaf, Serrano Anna, Lawson Christine, Thaker Maneesha, Alston Tricia, Bournazos Stylianos, Ravetch Jeffrey V, Fischetti Vincent A