日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling

一项针对122341名欧洲血统患者的主要焦虑症的全基因组关联研究,发现了58个基因位点,并强调了GABA能信号传导的作用。

Strom, Nora I; Verhulst, Brad; Bacanu, Silviu-Alin; Cheesman, Rosa; Purves, Kirstin L; Gedik, Hüseyin; Mitchell, Brittany L; Kwong, Alex S; Faucon, Annika B; Singh, Kritika; Medland, Sarah; Colodro-Conde, Lucia; Krebs, Kristi; Hoffmann, Per; Herms, Stefan; Gehlen, Jan; Ripke, Stephan; Awasthi, Swapnil; Palviainen, Teemu; Tasanko, Elisa M; Peterson, Roseann E; Adkins, Daniel E; Shabalin, Andrey A; Adams, Mark J; Iveson, Matthew H; Campbell, Archie; Thomas, Laurent F; Winsvold, Bendik S; Drange, Ole Kristian; Børte, Sigrid; Ter Kuile, Abigail R; Naamanka, Joonas; Nguyen, Tan-Hoang; Meier, Sandra M; Corfield, Elizabeth C; Hannigan, Laurie; Levey, Daniel F; Czamara, Darina; Weber, Heike; Choi, Karmel W; Pistis, Giorgio; Couvy-Duchesne, Baptiste; Van der Auwera, Sandra; Teumer, Alexander; Karlsson, Robert; Garcia-Argibay, Miguel; Lee, Donghyung; Wang, Rujia; Bjerkeset, Ottar; Stordal, Eystein; Bäckman, Julia; Salum, Giovanni A; Zai, Clement C; Kennedy, James L; Zai, Gwyneth; Tiwari, Arun K; Heilmann-Heimbach, Stefanie; Schmidt, Börge; Kaprio, Jaakko; Kennedy, Martin M; Boden, Joseph; Havdahl, Alexandra; Middeldorp, Christel M; Lopes, Fabiana L; Akula, Nirmala; McMahon, Francis J; Binder, Elisabeth B; Fehm, Lydia; Ströhle, Andreas; Castelao, Enrique; Tiemeier, Henning; Stein, Dan J; Whiteman, David; Olsen, Catherine; Fuller, Zachary; Wang, Xin; Wray, Naomi R; Byrne, Enda M; Lewis, Glyn; Timpson, Nicholas J; Davis, Lea K; Hickie, Ian B; Gillespie, Nathan A; Milani, Lili; Schumacher, Johannes; Woldbye, David P; Forstner, Andreas J; Nöthen, Markus M; Hovatta, Iiris; Horwood, John; Copeland, William E; Maes, Hermine H; McIntosh, Andrew M; Andreassen, Ole A; Zwart, John-Anker; Mors, Ole; Børglum, Anders D; Mortensen, Preben B; Ask, Helga; Reichborn-Kjennerud, Ted; Najman, Jackob M; Stein, Murray B; Gelernter, Joel; Milaneschi, Yuri; Penninx, Brenda W; Boomsma, Dorret I; Maron, Eduard; Erhardt-Lehmann, Angelika; Rück, Christian; Kircher, Tilo T; Melzig, Christiane A; Alpers, Georg W; Arolt, Volker; Domschke, Katharina; Smoller, Jordan W; Preisig, Martin; Martin, Nicholas G; Lupton, Michelle K; Luik, Annemarie I; Reif, Andreas; Grabe, Hans J; Larsson, Henrik; Magnusson, Patrik K; Oldehinkel, Albertine J; Hartman, Catharina A; Breen, Gerome; Docherty, Anna R; Coon, Hilary; Conrad, Rupert; Lehto, Kelli; Deckert, Jürgen; Eley, Thalia C; Mattheisen, Manuel; Hettema, John M

Specificity of Polygenic Scores for Psychiatric Disorders Beyond Transdiagnostic Genetic Risk

多基因评分对精神疾病的特异性超越了跨诊断遗传风险

Keser, Engin; Liao, Wangjingyi; Allegrini, Andrea G; Eley, Thalia C; Rimfeld, Kaili; Malanchini, Margherita; Plomin, Robert

How are children's perceptions of the home environment associated with a general psychopathology factor across childhood?

儿童对家庭环境的感知与儿童时期的一般心理病理因素之间有何关联?

Nejand, Jack K; Malanchini, Margherita; Voronin, Ivan; Eley, Thalia C; Rimfeld, Kaili

Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypes

单卵双胞胎的遗传学研究揭示了环境敏感性对精神和神经发育表型的影响

Assary, Elham; Coleman, Jonathan R I; Hemani, Gibran; van de Weijer, Margot P; Howe, Laurence J; Palviainen, Teemu; Grasby, Katrina L; Ahlskog, Rafael; Nygaard, Marianne; Cheesman, Rosa; Lim, Kai; Reynolds, Chandra A; Ordoñana, Juan R; Colodro-Conde, Lucia; Gordon, Scott; Madrid-Valero, Juan J; Thalamuthu, Anbupalam; Hottenga, Jouke-Jan; Mengel-From, Jonas; Armstrong, Nicola J; Sachdev, Perminder S; Lee, Teresa; Brodaty, Henry; Trollor, Julian N; Wright, Margaret; Ames, David; Catts, Vibeke S; Latvala, Antti; Vuoksimaa, Eero; Mallard, Travis; Paige Harden, K; Tucker-Drob, Elliot M; Oskarsson, Sven; Hammond, Christopher J; Christensen, Kaare; Taylor, Mark; Lundström, Sebastian; Larsson, Henrik; Karlsson, Robert; Pedersen, Nancy L; Mather, Karen A; Medland, Sarah E; Boomsma, Dorret I; Martin, Nicholas G; Plomin, Robert; Bartels, Meike; Lichtenstein, Paul; Kaprio, Jaakko; Eley, Thalia C; Davies, Neil M; Munroe, Patricia B; Keers, Robert

Sex-stratified genome-wide association meta-analysis of major depressive disorder

按性别分层的全基因组关联荟萃分析:重度抑郁症

Thomas, Jodi T; Thorp, Jackson G; Huider, Floris; Grimes, Poppy Z; Wang, Rujia; Youssef, Pierre; Coleman, Jonathan R I; Byrne, Enda M; Adams, Mark; Medland, Sarah E; Hickie, Ian B; Olsen, Catherine M; Whiteman, David C; Whalley, Heather C; Penninx, Brenda W J H; van Loo, Hanna M; Derks, Eske M; Eley, Thalia C; Breen, Gerome; Boomsma, Dorret I; Wray, Naomi R; Martin, Nicholas G; Mitchell, Brittany L

Genetic overlap between functional impairment and depression and anxiety symptom severity: evidence from the GLAD Study

功能障碍与抑郁和焦虑症状严重程度之间的遗传重叠:来自GLAD研究的证据

Skelton, Megan; Mundy, Jessica; Ter Kuile, Abigail R; Adey, Brett N; Armour, Chérie; Buckman, Joshua E J; Coleman, Jonathan R I; Davies, Molly R; Hirsch, Colette R; Hotopf, Matthew; Jones, Ian R; Kalsi, Gursharan; Krebs, Georgina; Lee, Sang Hyuck; Lin, Yuhao; McIntosh, Andrew M; Peel, Alicia J; Rayner, Christopher; Rimes, Katharine A; Smith, Daniel J; Thompson, Katherine N; Veale, David; Walters, James T R; Hübel, Christopher; Breen, Gerome; Eley, Thalia C

Neurodevelopmental and Psychosocial Outcomes in Adolescence of Children with Early Diagnoses of ADHD, Autism, Dyscalculia and Dyslexia

早期诊断为注意力缺陷多动障碍、自闭症、计算障碍和阅读障碍的儿童在青少年时期的神经发育和社会心理结果

Cai, Yufei; Holmes, Joni; Michelini, Giorgia; Eley, Thalia C; Gathercole, Susan E

Using Bifactor Twin Modeling to Assess the Genetic and Environmental Dimensionality of Adult ADHD Symptoms

利用双因子双胞胎模型评估成人注意力缺陷多动症症状的遗传和环境维度

Knyspel, Jacob; Morneau-Vaillancourt, Geneviève; Eley, Thalia C

Sex-stratified genome-wide association meta-analysis of Major Depressive Disorder

按性别分层的全基因组关联荟萃分析:重度抑郁症

Thomas, Jodi T; Thorp, Jackson G; Huider, Floris; Grimes, Poppy Z; Wang, Rujia; Youssef, Pierre; Coleman, Jonathan R I; Byrne, Enda M; Adams, Mark; Medland, Sarah E; Hickie, Ian B; Olsen, Catherine M; Whiteman, David C; Whalley, Heather C; Penninx, Brenda Wjh; van Loo, Hanna M; Derks, Eske M; Eley, Thalia C; Breen, Gerome; Boomsma, Dorret I; Wray, Naomi R; Martin, Nicholas G; Mitchell, Brittany L

Polygenic Scores and Networks of Psychopathology Symptoms

多基因评分和精神病理症状网络

Piazza, Giulia G; Allegrini, Andrea G; Eley, Thalia C; Epskamp, Sacha; Fried, Eiko; Isvoranu, Adela-Maria; Roiser, Jonathan P; Pingault, Jean-Baptiste