日期 影响因子
日期:
2020 年 — 2026 年
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影响因子:
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Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism.

未结合配体的原蛋白转化酶弗林蛋白酶的结构表明，其激活是通过底物诱导机制实现的

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1613630113
Dahms Sven O, Arciniega Marcelino, Steinmetzer Torsten, Huber Robert, Than Manuel E
免疫/内分泌
发表日期：2016
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Identification of inhibitors of the transmembrane protease FlaK of Methanococcus maripaludis

鉴定沼泽甲烷球菌跨膜蛋白酶FlaK的抑制剂

期刊:Microbiologyopen
影响因子:4.6
doi:10.1002/mbo3.358
Coburger, Ina; Schaub, Yvonne; Roeser, Dirk; Hardes, Kornelia; Maeder, Patrick; Klee, Nina; Steinmetzer, Torsten; Imhof, Diana; Diederich, Wibke E; Than, Manuel E
发表日期：2016
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X-ray structures of human furin in complex with competitive inhibitors

人弗林蛋白酶与竞争性抑制剂复合物的X射线晶体结构

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/cb500087x
Dahms, Sven O; Hardes, Kornelia; Becker, Gero L; Steinmetzer, Torsten; Brandstetter, Hans; Than, Manuel E
发表日期：2014
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Crystal structure of the antimicrobial peptidase lysostaphin from Staphylococcus simulans

模拟葡萄球菌抗菌肽酶溶菌酶的晶体结构

期刊:
影响因子:
doi:10.1111/febs.12929
Sabala, Izabela; Jagielska, Elzbieta; Bardelang, Philip T; Czapinska, Honorata; Dahms, Sven O; Sharpe, Jason A; James, Richard; Than, Manuel E; Thomas, Neil R; Bochtler, Matthias
发表日期：2014
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New furin inhibitors based on weakly basic amidinohydrazones

基于弱碱性脒基腙的新型弗林蛋白酶抑制剂

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2010.11.092
Sielaff, Frank; Than, Manuel E; Bevec, Dorian; Lindberg, Iris; Steinmetzer, Torsten
发表日期：2011
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Potent inhibitors of furin and furin-like proprotein convertases containing decarboxylated P1 arginine mimetics

含有脱羧P1精氨酸模拟物的强效弗林蛋白酶和弗林蛋白酶样前蛋白转化酶抑制剂

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm9012455
Becker, Gero L; Sielaff, Frank; Than, Manuel E; Lindberg, Iris; Routhier, Sophie; Day, Robert; Lu, Yinghui; Garten, Wolfgang; Steinmetzer, Torsten
发表日期：2010
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The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link

人胎盘胶原蛋白IV的非胶原（NC1）结构域的1.9 Å晶体结构显示，其稳定性是通过一种新型的共价Met-Lys交联实现的。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.062183499
Than, Manuel E; Henrich, Stefan; Huber, Robert; Ries, Albert; Mann, Karlheinz; Kühn, Klaus; Timpl, Rupert; Bourenkov, Gleb P; Bartunik, Hans D; Bode, Wolfram
发表日期：2002
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