日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Prolonged Zika Virus NS1 Protein Circulation in Patient Sera Impacts Clinical Outcome Before the Rise of a Specific IgM Response

寨卡病毒NS1蛋白在患者血清中长期循环,在特异性IgM抗体反应出现之前即可影响临床结局。

Tamietti, Carole; Stephen, Tharshana; Rouvinski, Alexander; Tenebray, Bernard; Leparc-Goffard, Isabelle; de Laval, Franck; Fernandes-Pellerin, Sandrine; Manuguerra, Jean-Claude; Rey, Félix; Hasan, Milena; Badaut, Cyril; Flamand, Marie; Matheus, Séverine; Briolant, Sébastien

IL-23 tunes inflammatory functions of human mucosal-associated invariant T cells

IL-23调节人黏膜相关不变T细胞的炎症功能

Laetitia Camard ,Tharshana Stephen ,Hanane Yahia-Cherbal ,Vincent Guillemot ,Sébastien Mella ,Victoire Baillet ,Hélène Lopez-Maestre ,Daniele Capocefalo ,Laura Cantini ,Claire Leloup ,Julie Marsande ,Katherine Garro ,Juan Sienes Bailo ,Ambre Dangien ,Natalia Pietrosemoli ,Milena Hasan ,Huimeng Wang ,Sidonia B G Eckle ,Anne M Fourie ,Carrie Greving ,Barbara Joyce-Shaikh ,Raphaelle Parker ,Daniel J Cua ,Elisabetta Bianchi ,Lars Rogge

In vivo deletion of a GWAS-identified Myb distal enhancer acts on Myb expression, globin switching, and clinical erythroid parameters in β-thalassemia

体内敲除 GWAS 鉴定的 Myb 远端增强子会影响 β-地中海贫血患者的 Myb 表达、珠蛋白转换和临床红系参数。

Deleuze, Virginie; Stephen, Tharshana; Salma, Mohammad; Orfeo, Cédric; Jorna, Ruud; Maas, Alex; Barroca, Vilma; Arcangeli, Marie-Laure; Lecellier, Charles-Henri; Andrieu-Soler, Charlotte; Grosveld, Frank; Soler, Eric

Distinct single-component adjuvants steer human DC-mediated T-cell polarization via Toll-like receptor signaling toward a potent antiviral immune response

不同的单组分佐剂通过 Toll 样受体信号通路引导人树突状细胞介导的 T 细胞极化,从而产生强效的抗病毒免疫反应。

Roßmann, Laura; Bagola, Katrin; Stephen, Tharshana; Gerards, Anna-Lisa; Walber, Bianca; Ullrich, Anja; Schülke, Stefan; Kamp, Christel; Spreitzer, Ingo; Hasan, Milena; David-Watine, Brigitte; Shorte, Spencer L; Bastian, Max; van Zandbergen, Ger

Unveiling Interindividual Variability of Human Fibroblast Innate Immune Response Using Robust Cell-Based Protocols

利用强大的基于细胞的协议揭示人类成纤维细胞先天免疫反应的个体间变异

Audrey Chansard, Nelly Dubrulle, Mathilde Poujol de Molliens, Pierre B Falanga, Tharshana Stephen, Milena Hasan, Ger van Zandbergen, Nathalie Aulner, Spencer L Shorte, Brigitte David-Watine

NFAT primes the human RORC locus for RORγt expression in CD4+ T cells

NFAT 启动人类 RORC 基因座在 CD4+ T 细胞中表达 RORγt

Hanane Yahia-Cherbal, Magda Rybczynska, Domenica Lovecchio, Tharshana Stephen, Chloé Lescale, Katarzyna Placek, Jérome Larghero, Lars Rogge, Elisabetta Bianchi

An unusual cause of isolated secondary ovarian failure due to cerebral toxoplasmosis in an African woman with AIDS

非洲艾滋病女性因脑弓形虫病导致孤立性继发性卵巢功能衰竭的罕见病因

Yoganathan, Katie Tharshana; Sadiq, Shaheena; Yoganathan, Kathir G

Control of developmentally primed erythroid genes by combinatorial co-repressor actions

通过组合辅阻遏物作用控制发育引发的红细胞基因

Ralph Stadhouders, Alba Cico, Tharshana Stephen, Supat Thongjuea, Petros Kolovos, H Irem Baymaz, Xiao Yu, Jeroen Demmers, Karel Bezstarosti, Alex Maas, Vilma Barroca, Christel Kockx, Zeliha Ozgur, Wilfred van Ijcken, Marie-Laure Arcangeli, Charlotte Andrieu-Soler, Boris Lenhard, Frank Grosveld, Eric

Complete heart block in dengue complicating management of shock due to both bleeding and leakage: a case report

登革热并发完全性房室传导阻滞,出血和渗漏导致休克,治疗难度加大:病例报告

Navinan, Mitrakrishnan Rayno; Yudhishdran, Jevon; Herath, Sandamalee; Liyanage, Isurujith; Kugadas, Tharshana; Kumara, Damith; Kulatunga, Aruna