日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Discovery of the SARS-CoV-2 Papain-Like Protease Inhibitor MR1-114: From Structure-Based Design to In Vivo Antiviral Efficacy

SARS-CoV-2木瓜蛋白酶样蛋白酶抑制剂MR1-114的发现：从基于结构的药物设计到体内抗病毒功效

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c03846
Gannarapu, Malla Reddy; Indukuri, Divakar; Holberg, Cameron; Ratia, Kiira; Ramos, Omar Lozano; Cardoza, Savio; Velma, Ganga Reddy; Musku, Soumya Reddy; Qi, Zuohuang; Slilaty, Steve; Li, Zuomei; Rong, Lijun; Thatcher, Gregory R J; Xiong, Rui
微生物学
SARS-CoV-2
发表日期：2026
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Cell-based high-content approach for SARS-CoV-2 neutralization identifies unique monoclonal antibodies and PI3K pathway inhibitors

基于细胞的高内涵方法鉴定出SARS-CoV-2中和作用的独特单克隆抗体和PI3K通路抑制剂

期刊:Frontiers in Cell and Developmental Biology
影响因子:4.3
doi:10.3389/fcell.2025.1538934
Cabel, Carly R; Guzman, Briana A; Alizadeh, Elaheh; Li, Shuaizhi; Holberg, Cameron; Wichaidit, Chonlarat; Cusanovich, Darren A; Paek, Andrew L; Thatcher, Gregory R J; Van Doorslaer, Koenraad; Nargi, Rachel S; Sutton, Rachel E; Suryadevara, Naveenchandra; Crowe, James E Jr; Carnahan, Robert H; Campos, Samuel K; Thorne, Curtis A
单克隆抗体
信号转导
细胞生物学
SARS-CoV-2
发表日期：2025
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Development of a high-throughput TR-FRET assay to identify inhibitors of the FAK-paxillin protein-protein interaction.

开发高通量 TR-FRET 检测方法，以鉴定 FAK-paxillin 蛋白-蛋白相互作用的抑制剂

期刊:SLAS Discovery
影响因子:2.7
doi:10.1016/j.slasd.2025.100237
Aromokeye Rukayat, Ackerman-Berrier Martha, Araujo Rosa Del Carmen, Lambousis Maria, Cardoza Savio, Chen L Charlie, Kaplan Matthew E, Zhu Haining, Penton Christopher, Zerbinatti Celina, Thatcher Gregory R J, Marlowe Timothy
免疫/内分泌
发表日期：2025
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In search of nonlipogenic ABCA1 inducers (NLAI): precision coregulator TR-FRET identifies diverse signatures for LXR ligands

寻找非脂肪生成性ABCA1诱导剂（NLAI）：精准共调节器TR-FRET识别LXR配体的多种特征

期刊:
影响因子:
doi:10.1101/2025.09.12.675753
Laham, Megan S; Ackerman-Berrier, Martha; Alam, Fahmida; Turner, Sarah; Velma, Ganga Reddy; Penton, Christopher; Musku, Soumya Reddy; Rana, Manan; Kumar, Senthil; Annadurai, Anandhan; Sulaiman, Maha Ibrahim; Ma, Nina; Thatcher, Gregory R J
ABCA1
RET
发表日期：2025
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The "Doorstop Pocket" In Thioredoxin Reductases─An Unexpected Druggable Regulator of the Catalytic Machinery

硫氧还蛋白还原酶中的“门挡口袋”——催化机制中一个意想不到的可成药调节因子

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.4c00669
Ardini, Matteo; Aboagye, Sammy Y; Petukhova, Valentina Z; Kastrati, Irida; Ippoliti, Rodolfo; Thatcher, Gregory R J; Petukhov, Pavel A; Williams, David L; Angelucci, Francesco
发表日期：2024
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Channeling Nicotinamide Phosphoribosyltransferase (NAMPT) to Address Life and Death

利用烟酰胺磷酸核糖转移酶 (NAMPT) 来应对生死问题

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.3c02112
Velma, Ganga Reddy; Krider, Isabella S; Alves, Erick T M; Courey, Jenna M; Laham, Megan S; Thatcher, Gregory R J
NAMPT
发表日期：2024
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Nicotinamide Phosphoribosyltransferase Positive Allosteric Modulators Attenuate Neuronal Oxidative Stress

烟酰胺磷酸核糖转移酶正向变构调节剂可减轻神经元氧化应激

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.3c00391
Gordon-Blake, Jesse; Ratia, Kiira; Weidig, Victoria; Velma, Ganga Reddy; Ackerman-Berrier, Martha; Penton, Christopher; Musku, Soumya Reddy; Alves, Erick T M; Driver, Tom; Tai, Leon; Thatcher, Gregory R J
毒理研究
神经科学
氧化应激
发表日期：2024
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Estradiol improves behavior in FAD transgenic mice that express APOE3 but not APOE4 after ovariectomy

卵巢切除术后，雌二醇可改善表达APOE3但不表达APOE4的FAD转基因小鼠的行为。

期刊:Frontiers in Endocrinology
影响因子:
doi:10.3389/fendo.2024.1374825
Balu, Deebika; Valencia-Olvera, Ana C; Deshpande, Ashwini; Narayanam, Saharsh; Konasani, Sravya; Pattisapu, Shreya; York, Jason M; Thatcher, Gregory R J; LaDu, Mary Jo; Tai, Leon M
APOE
发表日期：2024
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Inhibition of ACAT as a Therapeutic Target for Alzheimer's Disease Is Independent of ApoE4 Lipidation

抑制ACAT作为阿尔茨海默病治疗靶点与ApoE4脂化无关。

期刊:Neurotherapeutics
影响因子:6.9
doi:10.1007/s13311-023-01375-3
Valencia-Olvera, Ana C; Balu, Deebika; Faulk, Naomi; Amiridis, Aspasia; Wang, Yueting; Pham, Christine; Avila-Munoz, Eva; York, Jason M; Thatcher, Gregory R J; LaDu, Mary Jo
阿尔茨海默症
发表日期：2023
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Synthesis, Optimization, and Structure-Activity Relationships of Nicotinamide Phosphoribosyltransferase (NAMPT) Positive Allosteric Modulators (N-PAMs)

烟酰胺磷酸核糖转移酶（NAMPT）正变构调节剂（N-PAMs）的合成、优化及构效关系

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.3c01406
Shen, Zhengnan; Ratia, Kiira; Krider, Isabella; Ackerman-Berrier, Martha; Penton, Christopher; Musku, Soumya Reddy; Gordon-Blake, Jesse M; Laham, Megan S; Christie, Nicholas; Ma, Nina; Fu, Jiqiang; Xiong, Rui; Courey, Jenna M; Velma, Ganga Reddy; Thatcher, Gregory R J
NAMPT
发表日期：2023
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