日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

High-Throughput In Vivo Screening Using Barcoded mRNA Identifies Lipid Nanoparticles With Extrahepatic Tropism for In Situ Immunoengineering

利用条形码mRNA进行高通量体内筛选,鉴定出具有肝外趋向性的脂质纳米颗粒,用于原位免疫工程

Hamilton, Alex G; Thatte, Ajay S; Xu, Junchao; Luo, Zhangyi; Safford, Hannah C; Swingle, Kelsey L; Muscat-Rivera, Jenna; Kegel, Michael; Han, Xuexiang; Joseph, Ryann A; Murray, Amanda M; Geisler, Hannah C; Whitaker, Ricardo C; Xue, Lulu; Spektor, Roman; Melamed, Jilian R; Weissman, Drew; Mitchell, Michael J

Examining the effect of lipid nanoparticle elasticity on endocytosis and mRNA delivery to cancer cells

研究脂质纳米颗粒弹性对癌细胞内吞作用和mRNA递送的影响

Si, Changfeng; Beaumont, Elvie F P; Tan, Jenn Zi Yu; Demchuk, Mitchell J; Hudson, Zachary M; Shuler, Cecilia F; Safford, Hannah C; Thatte, Ajay S; Ang, Melgious; Mitchell, Michael J

Nanoparticle-Based Tolerogenic Vaccines: Next-Generation Strategies for Autoimmune and Allergic Disease Therapies

基于纳米颗粒的耐受性疫苗:自身免疫性疾病和过敏性疾病治疗的下一代策略

Nachod, Benjamin E; Thatte, Ajay S; Palanki, Rohan; Mitchell, Michael J

To modify or not to modify: Rethinking mRNA design for CAR T cell engineering

修改还是不修改:重新思考用于CAR T细胞工程的mRNA设计

Thatte, Ajay S; Mitchell, Michael J

Examining the effect of lipid nanoparticle elasticity on endocytosis and mRNA delivery to cancer cells

研究脂质纳米颗粒弹性对癌细胞内吞作用和mRNA递送的影响

Shuler, Cecilia F; Safford, Hannah C; Thatte, Ajay S; Ang, Melgious; Mitchell, Michael J

Examining the effect of lipid nanoparticle elasticity on endocytosis and mRNA delivery to cancer cells

研究脂质纳米颗粒弹性对癌细胞内吞作用和mRNA递送的影响

Pomeroy, Mary Louise; Hoffman, Carolyn Faith; Vunnam, Sravya; Moyo, Axucillia; Butler, Kathleen; Weinstein, Ali A; Goldberg, Debora Goetz; Shuler, Cecilia F; Safford, Hannah C; Thatte, Ajay S; Ang, Melgious; Mitchell, Michael J

Resolving heterogeneity of targeted lipid nanoparticles through solution-based biophysical analyses

通过溶液生物物理分析解决靶向脂质纳米颗粒的异质性问题

Geisler, Hannah C; Safford, Hannah C; Thatte, Ajay S; Padilla, Marshall S; Battistini, Elisa; Yamagata, Hannah M; Ullman, Violet M; Chan, Alex; Nachod, Benjamin E; Agrawal, Anushka; Watkins, Maxwell B; Hopkins, Jesse B; Tsourkas, Andrew; Gupta, Kushol; Mitchell, Michael

Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia.

胎盘趋向性 VEGF mRNA 脂质纳米颗粒可改善小鼠先兆子痫

Swingle Kelsey L, Hamilton Alex G, Safford Hannah C, Geisler Hannah C, Thatte Ajay S, Palanki Rohan, Murray Amanda M, Han Emily L, Mukalel Alvin J, Han Xuexiang, Joseph Ryann A, Ghalsasi Aditi A, Alameh Mohamad-Gabriel, Weissman Drew, Mitchell Michael J

Circular RNA lipid nanoparticle vaccine against SARS-CoV-2

针对SARS-CoV-2的环状RNA脂质纳米颗粒疫苗

Swingle, Kelsey L; Hamilton, Alex G; Han, Xuexiang; Liao, Kuo-Chieh; Safford, Hannah C; Thatte, Ajay S; Geisler, Hannah C; Xu, Junchao; Saw, Tzuen Yih; Wan, Yue; Mitchell, Michael J

Probing the Role of Lipid Nanoparticle Elasticity on mRNA Delivery to the Placenta

探究脂质纳米颗粒弹性对胎盘mRNA递送的作用

Safford, Hannah C; Shuler, Cecilia F; Geisler, Hannah C; Thatte, Ajay S; Swingle, Kelsey L; Han, Emily L; Murray, Amanda M; Hamilton, Alex G; Yamagata, Hannah M; Mitchell, Michael J