日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mapping genotypes to chromatin accessibility profiles in single cells

将基因型映射到单细胞染色质可及性图谱

Franco Izzo # ,Robert M Myers # ,Saravanan Ganesan # ,Levan Mekerishvili # ,Sanjay Kottapalli ,Tamara Prieto ,Elliot O Eton ,Theo Botella ,Andrew J Dunbar ,Robert L Bowman ,Jesus Sotelo ,Catherine Potenski ,Eleni P Mimitou ,Maximilian Stahl ,Sebastian El Ghaity-Beckley ,JoAnn Arandela ,Ramya Raviram ,Daniel C Choi ,Ronald Hoffman ,Ronan Chaligné ,Omar Abdel-Wahab ,Peter Smibert ,Irene M Ghobrial ,Joseph M Scandura ,Bridget Marcellino ,Ross L Levine ,Dan A Landau

Time-resolved fate mapping identifies the intestinal upper crypt zone as an origin of Lgr5+ crypt base columnar cells

时间分辨命运图谱分析表明,肠道上隐窝区是Lgr5+隐窝基底柱状细胞的起源地。

Claudia Capdevila ,Jonathan Miller ,Liang Cheng ,Adam Kornberg ,Joel J George ,Hyeonjeong Lee ,Theo Botella ,Christine S Moon ,John W Murray ,Stephanie Lam ,Ruben I Calderon ,Ermanno Malagola ,Gary Whelan ,Chyuan-Sheng Lin ,Arnold Han ,Timothy C Wang ,Peter A Sims ,Kelley S Yan

Genotype-to-phenotype mapping of somatic clonal mosaicism via single-cell co-capture of DNA mutations and mRNA transcripts

通过单细胞共捕获 DNA 突变和 mRNA 转录本实现体细胞克隆嵌合体的基因型到表型映射

Dennis J Yuan, John Zinno, Theo Botella, Dalia Dhingra, Shu Wang, Allegra Hawkins, Ariel Swett, Jesus Sotelo, Ramya Raviram, Clayton Hughes, Catherine Potenski, Akira Yokoyama, Nobuyuki Kakiuchi, Seishi Ogawa, Dan A Landau

Gluten induces rapid reprogramming of natural memory αβ and γδ intraepithelial T cells to induce cytotoxicity in celiac disease

麸质诱导自然记忆 αβ 和 γδ 上皮内 T 细胞快速重编程,从而诱发乳糜泻的细胞毒性

Adam Kornberg, Theo Botella, Christine S Moon, Samhita Rao, Jared Gelbs, Liang Cheng, Jonathan Miller, Alyssa M Bacarella, Javier A García-Vilas, Justin Vargas, Xuechen Yu, Izabela Krupska, Erin Bush, Reuben Garcia-Carrasquillo, Benjamin Lebwohl, Suneeta Krishnareddy, Suzanne Lewis, Peter H R Green,

Multiplexed single-cell analysis reveals prognostic and nonprognostic T cell types in human colorectal cancer

多重单细胞分析揭示了人类结直肠癌中具有预后意义和非预后意义的T细胞类型

Kazuya Masuda ,Adam Kornberg ,Jonathan Miller ,Sijie Lin ,Nathan Suek ,Theo Botella ,Kerim A Secener ,Alyssa M Bacarella ,Liang Cheng ,Matthew Ingham ,Vilma Rosario ,Ahmed M Al-Mazrou ,Steven A Lee-Kong ,Ravi P Kiran ,Marlon Stoeckius ,Peter Smibert ,Armando Del Portillo ,Paul E Oberstein ,Peter A Sims ,Kelley S Yan ,Arnold Han