日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Chemoproteomic development of SLC15A4 inhibitors with anti-inflammatory activity

利用化学蛋白质组学方法开发具有抗炎活性的SLC15A4抑制剂

Tzu-Yuan Chiu # ,Daniel C Lazar # ,Wesley W Wang # ,Jacob M Wozniak ,Appaso M Jadhav ,Weichao Li ,Nathalia Gazaniga ,Argyrios N Theofilopoulos ,John R Teijaro ,Christopher G Parker

[Influences and mechanism of berberine on wound healing of full-thickness skin defects in diabetic mice]

[小檗碱对糖尿病小鼠全层皮肤缺损伤口愈合的影响及机制]

Ogundare, Michael; Theofilopoulos, Spyridon; Lockhart, Andrew; Hall, Leslie J; Arenas, Ernest; Sjövall, Jan; Brenton, A Gareth; Wang, Yuqin; Griffiths, William J; 郑, 力铭; 刘, 钟元; 颜, 鸿宇; 李, 恒飞; 张, 志文

The solute carrier SLC15A4 is required for optimal trafficking of nucleic acid-sensing TLRs and ligands to endolysosomes

溶质载体SLC15A4是核酸感应TLR及其配体向内溶酶体最佳运输所必需的。

Rimann, Ivo; Gonzalez-Quintial, Rosana; Baccala, Roberto; Kiosses, William B; Teijaro, John R; Parker, Christopher G; Li, Xiaohong; Beutler, Bruce; Kono, Dwight H; Theofilopoulos, Argyrios N

The Cerebrospinal Fluid Profile of Cholesterol Metabolites in Parkinson's Disease and Their Association With Disease State and Clinical Features

帕金森病患者脑脊液胆固醇代谢物谱及其与疾病状态和临床特征的关系

William J Griffiths, Jonas Abdel-Khalik, Sarah F Moore, Ruwani S Wijeyekoon, Peter J Crick, Eylan Yutuc, Krista Farrell, David P Breen, Caroline H Williams-Gray, Spyridon Theofilopoulos, Ernest Arenas, Miles Trupp, Roger A Barker, Yuqin Wang

Mining for Oxysterols in Cyp7b1(-/-) Mouse Brain and Plasma: Relevance to Spastic Paraplegia Type 5

在Cyp7b1(-/-)小鼠脑和血浆中挖掘氧固醇:与痉挛性截瘫5型的相关性

Meljon, Anna; Crick, Peter J; Yutuc, Eylan; Yau, Joyce L; Seckl, Jonathan R; Theofilopoulos, Spyridon; Arenas, Ernest; Wang, Yuqin; Griffiths, William J

24(S),25-Epoxycholesterol and cholesterol 24S-hydroxylase (CYP46A1) overexpression promote midbrain dopaminergic neurogenesis in vivo

24(S)、25-环氧胆固醇和胆固醇 24S-羟化酶 (CYP46A1) 过表达促进体内中脑多巴胺能神经发生

Spyridon Theofilopoulos, Willy Antoni Abreu de Oliveira, Shanzheng Yang, Eylan Yutuc, Ahmed Saeed, Jonas Abdel-Khalik, Abbe Ullgren, Angel Cedazo-Minguez, Ingemar Björkhem, Yuqin Wang, William J Griffiths, Ernest Arenas

Silica exposure and chronic virus infection synergistically promote lupus-like systemic autoimmunity in mice with low genetic predisposition

二氧化硅暴露和慢性病毒感染协同促进低遗传易感性小鼠发生狼疮样系统性自身免疫性疾病

Gonzalez-Quintial, Rosana; Mayeux, Jessica M; Kono, Dwight H; Theofilopoulos, Argyrios N; Pollard, Kenneth M; Baccala, Roberto

Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1-/- mouse brain and plasma

甾醇代谢的其他途径:来自 Cyp27a1-/- 小鼠脑和血浆分析的证据

Griffiths, William J; Crick, Peter J; Meljon, Anna; Theofilopoulos, Spyridon; Abdel-Khalik, Jonas; Yutuc, Eylan; Parker, Josie E; Kelly, Diane E; Kelly, Steven L; Arenas, Ernest; Wang, Yuqin

The Matricellular Protein R-Spondin 2 Promotes Midbrain Dopaminergic Neurogenesis and Differentiation

基质细胞蛋白 R-Spondin 2 促进中脑多巴胺能神经发生和分化

Daniel Gyllborg, Maqsood Ahmed, Enrique M Toledo, Spyridon Theofilopoulos, Shanzheng Yang, Charles Ffrench-Constant, Ernest Arenas

Lupus acceleration by a MAVS-activating RNA virus requires endosomal TLR signaling and host genetic predisposition

MAVS 激活 RNA 病毒加速狼疮的发生需要内体 TLR 信号传导和宿主遗传易感性

Rosana Gonzalez-Quintial, Anthony Nguyen, Dwight H Kono, Michael B A Oldstone, Argyrios N Theofilopoulos, Roberto Baccala