日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The impact of DAMP-mediated inflammation in severe COVID-19 and related disorders

DAMP介导的炎症在重症COVID-19及相关疾病中的作用

Parthasarathy, Upasana; Martinelli, Roberta; Vollmann, Elisabeth H; Best, Katharine; Therien, Alex G

Immunomodulation by the Commensal Microbiome During Immune-Targeted Interventions: Focus on Cancer Immune Checkpoint Inhibitor Therapy and Vaccination

免疫靶向干预期间共生微生物组的免疫调节:聚焦癌症免疫检查点抑制剂疗法和疫苗接种

Reens, Abigail L; Cabral, Damien J; Liang, Xue; Norton, James E Jr; Therien, Alex G; Hazuda, Daria J; Swaminathan, Gokul

SARS-CoV-2 tropism, entry, replication, and propagation: Considerations for drug discovery and development

SARS-CoV-2 的嗜性、入侵、复制和传播:药物发现和开发中的考量

Murgolo, Nicholas; Therien, Alex G; Howell, Bonnie; Klein, Daniel; Koeplinger, Kenneth; Lieberman, Linda A; Adam, Gregory C; Flynn, Jessica; McKenna, Philip; Swaminathan, Gokul; Hazuda, Daria J; Olsen, David B

Disease Progression and Resolution in Rodent Models of Clostridium difficile Infection and Impact of Antitoxin Antibodies and Vancomycin

艰难梭菌感染啮齿动物模型中的疾病进展和消退以及抗毒素抗体和万古霉素的影响

Warn, Peter; Thommes, Pia; Sattar, Abdul; Corbett, David; Flattery, Amy; Zhang, Zuo; Black, Todd; Hernandez, Lorraine D; Therien, Alex G

Broad coverage of genetically diverse strains of Clostridium difficile by actoxumab and bezlotoxumab predicted by in vitro neutralization and epitope modeling.

体外中和和表位建模预测actoxumab和bezlotoxumab对遗传多样性艰难梭菌菌株具有广泛的覆盖力

Hernandez Lorraine D, Racine Fred, Xiao Li, DiNunzio Edward, Hairston Nichelle, Sheth Payal R, Murgolo Nicholas J, Therien Alex G

Mechanism of action and epitopes of Clostridium difficile toxin B-neutralizing antibody bezlotoxumab revealed by X-ray crystallography

X射线晶体衍射揭示了艰难梭菌毒素B中和抗体贝洛妥珠单抗的作用机制和表位

Orth, Peter; Xiao, Li; Hernandez, Lorraine D; Reichert, Paul; Sheth, Payal R; Beaumont, Maribel; Yang, Xiaoyu; Murgolo, Nicholas; Ermakov, Grigori; DiNunzio, Edward; Racine, Fred; Karczewski, Jerzy; Secore, Susan; Ingram, Richard N; Mayhood, Todd; Strickland, Corey; Therien, Alex G