Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor
基于结构的IACS-9571设计：一种选择性高亲和力双重TRIM24-BRPF1溴结构域抑制剂
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5b00405
Palmer, Wylie S; Poncet-Montange, Guillaume; Liu, Gang; Petrocchi, Alessia; Reyna, Naphtali; Subramanian, Govindan; Theroff, Jay; Yau, Anne; Kost-Alimova, Maria; Bardenhagen, Jennifer P; Leo, Elisabetta; Shepard, Hannah E; Tieu, Trang N; Shi, Xi; Zhan, Yanai; Zhao, Shuping; Barton, Michelle C; Draetta, Giulio; Toniatti, Carlo; Jones, Philip; Geck Do, Mary; Andersen, Jannik N
